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P53203 (PEX31_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 90. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Peroxisomal membrane protein PEX31
Alternative name(s):
Peroxin-31
Gene names
Name:PEX31
Ordered Locus Names:YGR004W
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length462 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Peroxisome membrane; Multi-pass membrane protein Ref.3.

Miscellaneous

Present with 238 molecules/cell in log phase SD medium.

Sequence similarities

Belongs to the PEX28-32 family. PEX30/31 subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 462462Peroxisomal membrane protein PEX31
PRO_0000202779

Regions

Topological domain1 – 9090Cytoplasmic Potential
Transmembrane91 – 11121Helical; Potential
Topological domain112 – 17564Peroxisomal Potential
Transmembrane176 – 19621Helical; Potential
Topological domain197 – 462266Cytoplasmic Potential

Amino acid modifications

Modified residue4321Phosphoserine Ref.6 Ref.7 Ref.8
Modified residue4351Phosphothreonine Ref.8

Sequences

Sequence LengthMass (Da)Tools
P53203 [UniParc].

Last modified October 1, 1996. Version 1.
Checksum: 3F875D40748AB6C3

FASTA46252,943
        10         20         30         40         50         60 
MSEINNENLE PTSSTVAEST ESKNKHIRSA LRKRRGKLSA QTYEEDQEAI LSSPLLTSTP 

        70         80         90        100        110        120 
KTVSRSLVRL YPYLIVVDNF LSIITWSNDN VSANLLGIFL FTVCVLYFGF ITRYFGHLMI 

       130        140        150        160        170        180 
VGIIWVYLLI DKHVQETMAS CPSLDDIIHV MDRVSMKSSA VLSPITILSA QDVRRLLFTI 

       190        200        210        220        230        240 
AFLSPVYIFL TVFVLSPNYL MLIGGLYVLT YHSKLIRRMR RYLWKFRVVR LLVFFITGLD 

       250        260        270        280        290        300 
LGGPDNNRRL FASVNKKIRS FVWNEVGNTS NTKKTVLFKV ALFENQRRWL GIGWTSTMLS 

       310        320        330        340        350        360 
YERASWTDEF LNTSPSPEVF TLPEEQSGMA WEWHDKDWML DLTNDGIIQL PASAAKTKVK 

       370        380        390        400        410        420 
PGADEGFIYY DNTWNNPSAT DTYKKYTRRR RWIRTATVTT TYDDEPTVEK ATPNSHALKS 

       430        440        450        460 
EENNRVRKRK VSFSTANEVH IIPSSDSSKL IQISDVSMSP SL 

« Hide

References

« Hide 'large scale' references
[1]"The nucleotide sequence of Saccharomyces cerevisiae chromosome VII."
Tettelin H., Agostoni-Carbone M.L., Albermann K., Albers M., Arroyo J., Backes U., Barreiros T., Bertani I., Bjourson A.J., Brueckner M., Bruschi C.V., Carignani G., Castagnoli L., Cerdan E., Clemente M.L., Coblenz A., Coglievina M., Coissac E. expand/collapse author list , Defoor E., Del Bino S., Delius H., Delneri D., de Wergifosse P., Dujon B., Durand P., Entian K.-D., Eraso P., Escribano V., Fabiani L., Fartmann B., Feroli F., Feuermann M., Frontali L., Garcia-Gonzalez M., Garcia-Saez M.I., Goffeau A., Guerreiro P., Hani J., Hansen M., Hebling U., Hernandez K., Heumann K., Hilger F., Hofmann B., Indge K.J., James C.M., Klima R., Koetter P., Kramer B., Kramer W., Lauquin G., Leuther H., Louis E.J., Maillier E., Marconi A., Martegani E., Mazon M.J., Mazzoni C., McReynolds A.D.K., Melchioretto P., Mewes H.-W., Minenkova O., Mueller-Auer S., Nawrocki A., Netter P., Neu R., Nombela C., Oliver S.G., Panzeri L., Paoluzi S., Plevani P., Portetelle D., Portillo F., Potier S., Purnelle B., Rieger M., Riles L., Rinaldi T., Robben J., Rodrigues-Pousada C., Rodriguez-Belmonte E., Rodriguez-Torres A.M., Rose M., Ruzzi M., Saliola M., Sanchez-Perez M., Schaefer B., Schaefer M., Scharfe M., Schmidheini T., Schreer A., Skala J., Souciet J.-L., Steensma H.Y., Talla E., Thierry A., Vandenbol M., van der Aart Q.J.M., Van Dyck L., Vanoni M., Verhasselt P., Voet M., Volckaert G., Wambutt R., Watson M.D., Weber N., Wedler E., Wedler H., Wipfli P., Wolf K., Wright L.F., Zaccaria P., Zimmermann M., Zollner A., Kleine K.
Nature 387:81-84(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]"The reference genome sequence of Saccharomyces cerevisiae: Then and now."
Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R., Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S., Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.
G3 (Bethesda) 4:389-398(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[3]"Global analysis of protein localization in budding yeast."
Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K.
Nature 425:686-691(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[4]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[5]"A global topology map of the Saccharomyces cerevisiae membrane proteome."
Kim H., Melen K., Oesterberg M., von Heijne G.
Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
Strain: ATCC 208353 / W303-1A.
[6]"Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae."
Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J., Elias J.E., Gygi S.P.
J. Proteome Res. 6:1190-1197(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-432, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Strain: ADR376.
[7]"Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry."
Chi A., Huttenhower C., Geer L.Y., Coon J.J., Syka J.E.P., Bai D.L., Shabanowitz J., Burke D.J., Troyanskaya O.G., Hunt D.F.
Proc. Natl. Acad. Sci. U.S.A. 104:2193-2198(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-432, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[8]"Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution."
Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.
Science 325:1682-1686(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-432 AND THR-435, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z72789 Genomic DNA. Translation: CAA96987.1.
BK006941 Genomic DNA. Translation: DAA08102.1.
PIRS64293.
RefSeqNP_011518.1. NM_001181133.1.

3D structure databases

ProteinModelPortalP53203.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid33248. 43 interactions.
DIPDIP-5455N.
IntActP53203. 3 interactions.
MINTMINT-480826.
STRING4932.YGR004W.

Protein family/group databases

TCDB3.A.20.1.5. the peroxisomal protein importer (ppi) family.

Proteomic databases

MaxQBP53203.
PaxDbP53203.
PRIDEP53203.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYGR004W; YGR004W; YGR004W.
GeneID852887.
KEGGsce:YGR004W.

Organism-specific databases

CYGDYGR004w.
SGDS000003236. PEX31.

Phylogenomic databases

eggNOGNOG72309.
GeneTreeENSGT00390000017777.
HOGENOMHOG000180096.
OMATANEVHI.
OrthoDBEOG72VHGD.

Enzyme and pathway databases

BioCycYEAST:G3O-30735-MONOMER.

Gene expression databases

GenevestigatorP53203.

Family and domain databases

InterProIPR010482. Peroxin/Dysferlin.
IPR006614. Peroxin/Ferlin.
[Graphical view]
PfamPF06398. Pex24p. 1 hit.
[Graphical view]
SMARTSM00694. DysFC. 1 hit.
SM00693. DysFN. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio972544.

Entry information

Entry namePEX31_YEAST
AccessionPrimary (citable) accession number: P53203
Secondary accession number(s): D6VUE1
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: May 14, 2014
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome VII

Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families