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Protein

Peroxisomal membrane protein PEX31

Gene

PEX31

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

  • peroxisome organization Source: SGD
Complete GO annotation...

Enzyme and pathway databases

BioCyciYEAST:G3O-30735-MONOMER.

Protein family/group databases

TCDBi3.A.20.1.5. the peroxisomal protein importer (ppi) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Peroxisomal membrane protein PEX31
Alternative name(s):
Peroxin-31
Gene namesi
Name:PEX31
Ordered Locus Names:YGR004W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome VII

Organism-specific databases

EuPathDBiFungiDB:YGR004W.
SGDiS000003236. PEX31.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 90CytoplasmicSequence analysisAdd BLAST90
Transmembranei91 – 111HelicalSequence analysisAdd BLAST21
Topological domaini112 – 175PeroxisomalSequence analysisAdd BLAST64
Transmembranei176 – 196HelicalSequence analysisAdd BLAST21
Topological domaini197 – 462CytoplasmicSequence analysisAdd BLAST266

GO - Cellular componenti

  • integral component of peroxisomal membrane Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Peroxisome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002027791 – 462Peroxisomal membrane protein PEX31Add BLAST462

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei432PhosphoserineCombined sources1
Modified residuei435PhosphothreonineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiP53203.
PRIDEiP53203.
TopDownProteomicsiP53203.

PTM databases

iPTMnetiP53203.

Interactioni

Protein-protein interaction databases

BioGridi33248. 44 interactors.
DIPiDIP-5455N.
IntActiP53203. 3 interactors.
MINTiMINT-480826.

Structurei

3D structure databases

ProteinModelPortaliP53203.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PEX28-32 family. PEX30/31 subfamily.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

GeneTreeiENSGT00390000017777.
HOGENOMiHOG000180096.
InParanoidiP53203.
OMAiRWIRTAT.
OrthoDBiEOG092C1ACD.

Family and domain databases

InterProiIPR010482. Peroxin.
IPR006614. Peroxin/Ferlin.
[Graphical view]
PfamiPF06398. Pex24p. 1 hit.
[Graphical view]
SMARTiSM00694. DysFC. 1 hit.
SM00693. DysFN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P53203-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEINNENLE PTSSTVAEST ESKNKHIRSA LRKRRGKLSA QTYEEDQEAI
60 70 80 90 100
LSSPLLTSTP KTVSRSLVRL YPYLIVVDNF LSIITWSNDN VSANLLGIFL
110 120 130 140 150
FTVCVLYFGF ITRYFGHLMI VGIIWVYLLI DKHVQETMAS CPSLDDIIHV
160 170 180 190 200
MDRVSMKSSA VLSPITILSA QDVRRLLFTI AFLSPVYIFL TVFVLSPNYL
210 220 230 240 250
MLIGGLYVLT YHSKLIRRMR RYLWKFRVVR LLVFFITGLD LGGPDNNRRL
260 270 280 290 300
FASVNKKIRS FVWNEVGNTS NTKKTVLFKV ALFENQRRWL GIGWTSTMLS
310 320 330 340 350
YERASWTDEF LNTSPSPEVF TLPEEQSGMA WEWHDKDWML DLTNDGIIQL
360 370 380 390 400
PASAAKTKVK PGADEGFIYY DNTWNNPSAT DTYKKYTRRR RWIRTATVTT
410 420 430 440 450
TYDDEPTVEK ATPNSHALKS EENNRVRKRK VSFSTANEVH IIPSSDSSKL
460
IQISDVSMSP SL
Length:462
Mass (Da):52,943
Last modified:October 1, 1996 - v1
Checksum:i3F875D40748AB6C3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z72789 Genomic DNA. Translation: CAA96987.1.
BK006941 Genomic DNA. Translation: DAA08102.1.
PIRiS64293.
RefSeqiNP_011518.1. NM_001181133.1.

Genome annotation databases

EnsemblFungiiYGR004W; YGR004W; YGR004W.
GeneIDi852887.
KEGGisce:YGR004W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z72789 Genomic DNA. Translation: CAA96987.1.
BK006941 Genomic DNA. Translation: DAA08102.1.
PIRiS64293.
RefSeqiNP_011518.1. NM_001181133.1.

3D structure databases

ProteinModelPortaliP53203.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi33248. 44 interactors.
DIPiDIP-5455N.
IntActiP53203. 3 interactors.
MINTiMINT-480826.

Protein family/group databases

TCDBi3.A.20.1.5. the peroxisomal protein importer (ppi) family.

PTM databases

iPTMnetiP53203.

Proteomic databases

MaxQBiP53203.
PRIDEiP53203.
TopDownProteomicsiP53203.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYGR004W; YGR004W; YGR004W.
GeneIDi852887.
KEGGisce:YGR004W.

Organism-specific databases

EuPathDBiFungiDB:YGR004W.
SGDiS000003236. PEX31.

Phylogenomic databases

GeneTreeiENSGT00390000017777.
HOGENOMiHOG000180096.
InParanoidiP53203.
OMAiRWIRTAT.
OrthoDBiEOG092C1ACD.

Enzyme and pathway databases

BioCyciYEAST:G3O-30735-MONOMER.

Miscellaneous databases

PROiP53203.

Family and domain databases

InterProiIPR010482. Peroxin.
IPR006614. Peroxin/Ferlin.
[Graphical view]
PfamiPF06398. Pex24p. 1 hit.
[Graphical view]
SMARTiSM00694. DysFC. 1 hit.
SM00693. DysFN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPEX31_YEAST
AccessioniPrimary (citable) accession number: P53203
Secondary accession number(s): D6VUE1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: November 2, 2016
This is version 108 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 238 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome VII
    Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.