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P53195 (COG7_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 97. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Conserved oligomeric Golgi complex subunit 7

Short name=COG complex subunit 7
Alternative name(s):
Complexed with DOR1 protein 5
Component of oligomeric Golgi complex 7
Gene names
Name:COG7
Synonyms:COD5
Ordered Locus Names:YGL005C
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length279 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events.

Subunit structure

Component of the conserved oligomeric Golgi (COG or Sec34/Sec35) complex which consists of eight different proteins COG1-COG8. Ref.4

Subcellular location

Golgi apparatus membrane; Peripheral membrane protein By similarity.

Miscellaneous

Present with 1360 molecules/cell in log phase SD medium.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 279279Conserved oligomeric Golgi complex subunit 7
PRO_0000213520

Experimental info

Sequence conflict121D → G in AAT93150. Ref.3

Sequences

Sequence LengthMass (Da)Tools
P53195 [UniParc].

Last modified October 1, 1996. Version 1.
Checksum: A72B39889DC74625

FASTA27931,775
        10         20         30         40         50         60 
MVELTITGDD DDILSMFFDE EFVPHAFVDI LLSNALNEDQ IQTQSVSSLL LTRLDFYTKN 

        70         80         90        100        110        120 
LTKELESTIW NLDKLSQTLP RTWASSRYHK EAEQNDSSLY STESLKSSKL EYYLDTLASA 

       130        140        150        160        170        180 
VRALETGMHN VTEKLSDLDN ENNRNTNVRQ QLQSLMLIKE RIEKVVYYLE QVRTVTNIST 

       190        200        210        220        230        240 
VRENNTTSTG TDLSITDFRT SLKALEDTID ESLSSAIDNE AKDETNKDLI GRIDSLSELK 

       250        260        270 
CLFKGLDKFF AEYSNFSESI KSKAQSYLST KNIDDGMIS 

« Hide

References

« Hide 'large scale' references
[1]"The nucleotide sequence of Saccharomyces cerevisiae chromosome VII."
Tettelin H., Agostoni-Carbone M.L., Albermann K., Albers M., Arroyo J., Backes U., Barreiros T., Bertani I., Bjourson A.J., Brueckner M., Bruschi C.V., Carignani G., Castagnoli L., Cerdan E., Clemente M.L., Coblenz A., Coglievina M., Coissac E. expand/collapse author list , Defoor E., Del Bino S., Delius H., Delneri D., de Wergifosse P., Dujon B., Durand P., Entian K.-D., Eraso P., Escribano V., Fabiani L., Fartmann B., Feroli F., Feuermann M., Frontali L., Garcia-Gonzalez M., Garcia-Saez M.I., Goffeau A., Guerreiro P., Hani J., Hansen M., Hebling U., Hernandez K., Heumann K., Hilger F., Hofmann B., Indge K.J., James C.M., Klima R., Koetter P., Kramer B., Kramer W., Lauquin G., Leuther H., Louis E.J., Maillier E., Marconi A., Martegani E., Mazon M.J., Mazzoni C., McReynolds A.D.K., Melchioretto P., Mewes H.-W., Minenkova O., Mueller-Auer S., Nawrocki A., Netter P., Neu R., Nombela C., Oliver S.G., Panzeri L., Paoluzi S., Plevani P., Portetelle D., Portillo F., Potier S., Purnelle B., Rieger M., Riles L., Rinaldi T., Robben J., Rodrigues-Pousada C., Rodriguez-Belmonte E., Rodriguez-Torres A.M., Rose M., Ruzzi M., Saliola M., Sanchez-Perez M., Schaefer B., Schaefer M., Scharfe M., Schmidheini T., Schreer A., Skala J., Souciet J.-L., Steensma H.Y., Talla E., Thierry A., Vandenbol M., van der Aart Q.J.M., Van Dyck L., Vanoni M., Verhasselt P., Voet M., Volckaert G., Wambutt R., Watson M.D., Weber N., Wedler E., Wedler H., Wipfli P., Wolf K., Wright L.F., Zaccaria P., Zimmermann M., Zollner A., Kleine K.
Nature 387:81-84(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[3]"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae."
Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. expand/collapse author list , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J.
Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[4]"The Sec34/35 Golgi transport complex is related to the exocyst, defining a family of complexes involved in multiple steps of membrane traffic."
Whyte J.R., Munro S.
Dev. Cell 1:527-537(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBUNIT.
[5]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[6]"The binary interacting network of the conserved oligomeric Golgi tethering complex."
Loh E., Hong W.
J. Biol. Chem. 279:24640-24648(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: COMPOSITION OF THE COG COMPLEX, INTERACTION WITH COG4.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z72527 Genomic DNA. Translation: CAA96705.1.
AY693131 Genomic DNA. Translation: AAT93150.1.
BK006941 Genomic DNA. Translation: DAA08094.1.
PIRS64007.
RefSeqNP_011510.1. NM_001180870.1.

3D structure databases

ProteinModelPortalP53195.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid33240. 184 interactions.
DIPDIP-4580N.
IntActP53195. 8 interactions.
MINTMINT-573650.
STRING4932.YGL005C.

Proteomic databases

PaxDbP53195.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYGL005C; YGL005C; YGL005C.
GeneID852879.
KEGGsce:YGL005C.

Organism-specific databases

CYGDYGL005c.
SGDS000002973. COG7.

Phylogenomic databases

eggNOGNOG45611.
HOGENOMHOG000111883.
OMALVTHLDY.
OrthoDBEOG72RNB8.

Enzyme and pathway databases

BioCycYEAST:G3O-30529-MONOMER.

Gene expression databases

GenevestigatorP53195.

Family and domain databases

ProtoNetSearch...

Other

NextBio972520.

Entry information

Entry nameCOG7_YEAST
AccessionPrimary (citable) accession number: P53195
Secondary accession number(s): D6VUD3, E9P921
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: February 19, 2014
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome VII

Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD