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P53195

- COG7_YEAST

UniProt

P53195 - COG7_YEAST

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Protein

Conserved oligomeric Golgi complex subunit 7

Gene

COG7

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at protein leveli

Functioni

Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events.

GO - Biological processi

  1. CVT pathway Source: SGD
  2. intra-Golgi vesicle-mediated transport Source: SGD
Complete GO annotation...

Keywords - Biological processi

Protein transport, Transport

Enzyme and pathway databases

BioCyciYEAST:G3O-30529-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Conserved oligomeric Golgi complex subunit 7
Short name:
COG complex subunit 7
Alternative name(s):
Complexed with DOR1 protein 5
Component of oligomeric Golgi complex 7
Gene namesi
Name:COG7
Synonyms:COD5
Ordered Locus Names:YGL005C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome VII

Organism-specific databases

CYGDiYGL005c.
SGDiS000002973. COG7.

Subcellular locationi

GO - Cellular componenti

  1. Golgi transport complex Source: SGD
  2. membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 279279Conserved oligomeric Golgi complex subunit 7PRO_0000213520Add
BLAST

Proteomic databases

MaxQBiP53195.
PaxDbiP53195.

Expressioni

Gene expression databases

GenevestigatoriP53195.

Interactioni

Subunit structurei

Component of the conserved oligomeric Golgi (COG or Sec34/Sec35) complex which consists of eight different proteins COG1-COG8.1 Publication

Binary interactionsi

WithEntry#Exp.IntActNotes
COG2P532712EBI-4847,EBI-16614
COG3P400942EBI-4847,EBI-16605
COG4Q060962EBI-4847,EBI-4823
COG5P539516EBI-4847,EBI-4841
COG6P539593EBI-4847,EBI-4829
COG8Q046322EBI-4847,EBI-6035

Protein-protein interaction databases

BioGridi33240. 184 interactions.
DIPiDIP-4580N.
IntActiP53195. 8 interactions.
MINTiMINT-573650.
STRINGi4932.YGL005C.

Structurei

3D structure databases

ProteinModelPortaliP53195.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiNOG45611.
HOGENOMiHOG000111883.
InParanoidiP53195.
OMAiLVTHLDY.
OrthoDBiEOG72RNB8.

Sequencei

Sequence statusi: Complete.

P53195-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVELTITGDD DDILSMFFDE EFVPHAFVDI LLSNALNEDQ IQTQSVSSLL
60 70 80 90 100
LTRLDFYTKN LTKELESTIW NLDKLSQTLP RTWASSRYHK EAEQNDSSLY
110 120 130 140 150
STESLKSSKL EYYLDTLASA VRALETGMHN VTEKLSDLDN ENNRNTNVRQ
160 170 180 190 200
QLQSLMLIKE RIEKVVYYLE QVRTVTNIST VRENNTTSTG TDLSITDFRT
210 220 230 240 250
SLKALEDTID ESLSSAIDNE AKDETNKDLI GRIDSLSELK CLFKGLDKFF
260 270
AEYSNFSESI KSKAQSYLST KNIDDGMIS
Length:279
Mass (Da):31,775
Last modified:October 1, 1996 - v1
Checksum:iA72B39889DC74625
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti12 – 121D → G in AAT93150. (PubMed:17322287)Curated

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z72527 Genomic DNA. Translation: CAA96705.1.
AY693131 Genomic DNA. Translation: AAT93150.1.
BK006941 Genomic DNA. Translation: DAA08094.1.
PIRiS64007.
RefSeqiNP_011510.1. NM_001180870.1.

Genome annotation databases

EnsemblFungiiYGL005C; YGL005C; YGL005C.
GeneIDi852879.
KEGGisce:YGL005C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z72527 Genomic DNA. Translation: CAA96705.1 .
AY693131 Genomic DNA. Translation: AAT93150.1 .
BK006941 Genomic DNA. Translation: DAA08094.1 .
PIRi S64007.
RefSeqi NP_011510.1. NM_001180870.1.

3D structure databases

ProteinModelPortali P53195.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 33240. 184 interactions.
DIPi DIP-4580N.
IntActi P53195. 8 interactions.
MINTi MINT-573650.
STRINGi 4932.YGL005C.

Proteomic databases

MaxQBi P53195.
PaxDbi P53195.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YGL005C ; YGL005C ; YGL005C .
GeneIDi 852879.
KEGGi sce:YGL005C.

Organism-specific databases

CYGDi YGL005c.
SGDi S000002973. COG7.

Phylogenomic databases

eggNOGi NOG45611.
HOGENOMi HOG000111883.
InParanoidi P53195.
OMAi LVTHLDY.
OrthoDBi EOG72RNB8.

Enzyme and pathway databases

BioCyci YEAST:G3O-30529-MONOMER.

Miscellaneous databases

NextBioi 972520.

Gene expression databases

Genevestigatori P53195.

Family and domain databases

ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The nucleotide sequence of Saccharomyces cerevisiae chromosome VII."
    Tettelin H., Agostoni-Carbone M.L., Albermann K., Albers M., Arroyo J., Backes U., Barreiros T., Bertani I., Bjourson A.J., Brueckner M., Bruschi C.V., Carignani G., Castagnoli L., Cerdan E., Clemente M.L., Coblenz A., Coglievina M., Coissac E.
    , Defoor E., Del Bino S., Delius H., Delneri D., de Wergifosse P., Dujon B., Durand P., Entian K.-D., Eraso P., Escribano V., Fabiani L., Fartmann B., Feroli F., Feuermann M., Frontali L., Garcia-Gonzalez M., Garcia-Saez M.I., Goffeau A., Guerreiro P., Hani J., Hansen M., Hebling U., Hernandez K., Heumann K., Hilger F., Hofmann B., Indge K.J., James C.M., Klima R., Koetter P., Kramer B., Kramer W., Lauquin G., Leuther H., Louis E.J., Maillier E., Marconi A., Martegani E., Mazon M.J., Mazzoni C., McReynolds A.D.K., Melchioretto P., Mewes H.-W., Minenkova O., Mueller-Auer S., Nawrocki A., Netter P., Neu R., Nombela C., Oliver S.G., Panzeri L., Paoluzi S., Plevani P., Portetelle D., Portillo F., Potier S., Purnelle B., Rieger M., Riles L., Rinaldi T., Robben J., Rodrigues-Pousada C., Rodriguez-Belmonte E., Rodriguez-Torres A.M., Rose M., Ruzzi M., Saliola M., Sanchez-Perez M., Schaefer B., Schaefer M., Scharfe M., Schmidheini T., Schreer A., Skala J., Souciet J.-L., Steensma H.Y., Talla E., Thierry A., Vandenbol M., van der Aart Q.J.M., Van Dyck L., Vanoni M., Verhasselt P., Voet M., Volckaert G., Wambutt R., Watson M.D., Weber N., Wedler E., Wedler H., Wipfli P., Wolf K., Wright L.F., Zaccaria P., Zimmermann M., Zollner A., Kleine K.
    Nature 387:81-84(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  4. "The Sec34/35 Golgi transport complex is related to the exocyst, defining a family of complexes involved in multiple steps of membrane traffic."
    Whyte J.R., Munro S.
    Dev. Cell 1:527-537(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBUNIT.
  5. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
  6. "The binary interacting network of the conserved oligomeric Golgi tethering complex."
    Loh E., Hong W.
    J. Biol. Chem. 279:24640-24648(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: COMPOSITION OF THE COG COMPLEX, INTERACTION WITH COG4.

Entry informationi

Entry nameiCOG7_YEAST
AccessioniPrimary (citable) accession number: P53195
Secondary accession number(s): D6VUD3, E9P921
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: October 29, 2014
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 1360 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome VII
    Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names

External Data

Dasty 3