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Protein

Conserved oligomeric Golgi complex subunit 7

Gene

COG7

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events.

Miscellaneous

Present with 1360 molecules/cell in log phase SD medium.1 Publication

GO - Biological processi

  • intra-Golgi vesicle-mediated transport Source: SGD
  • protein localization by the Cvt pathway Source: SGD
  • protein transport Source: UniProtKB-KW

Keywordsi

Biological processProtein transport, Transport

Enzyme and pathway databases

BioCyciYEAST:G3O-30529-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Conserved oligomeric Golgi complex subunit 7
Short name:
COG complex subunit 7
Alternative name(s):
Complexed with DOR1 protein 5
Component of oligomeric Golgi complex 7
Gene namesi
Name:COG7
Synonyms:COD5
Ordered Locus Names:YGL005C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi

Organism-specific databases

EuPathDBiFungiDB:YGL005C
SGDiS000002973 COG7

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002135201 – 279Conserved oligomeric Golgi complex subunit 7Add BLAST279

Proteomic databases

MaxQBiP53195
PaxDbiP53195
PRIDEiP53195

PTM databases

iPTMnetiP53195

Interactioni

Subunit structurei

Component of the conserved oligomeric Golgi (COG or Sec34/Sec35) complex which consists of eight different proteins COG1-COG8.1 Publication

Binary interactionsi

Show more details

Protein-protein interaction databases

BioGridi33240, 342 interactors
DIPiDIP-4580N
IntActiP53195, 8 interactors
MINTiP53195
STRINGi4932.YGL005C

Structurei

3D structure databases

ProteinModelPortaliP53195
SMRiP53195
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000111883
InParanoidiP53195
OMAiSSKLEYY
OrthoDBiEOG092C5M66

Sequencei

Sequence statusi: Complete.

P53195-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVELTITGDD DDILSMFFDE EFVPHAFVDI LLSNALNEDQ IQTQSVSSLL
60 70 80 90 100
LTRLDFYTKN LTKELESTIW NLDKLSQTLP RTWASSRYHK EAEQNDSSLY
110 120 130 140 150
STESLKSSKL EYYLDTLASA VRALETGMHN VTEKLSDLDN ENNRNTNVRQ
160 170 180 190 200
QLQSLMLIKE RIEKVVYYLE QVRTVTNIST VRENNTTSTG TDLSITDFRT
210 220 230 240 250
SLKALEDTID ESLSSAIDNE AKDETNKDLI GRIDSLSELK CLFKGLDKFF
260 270
AEYSNFSESI KSKAQSYLST KNIDDGMIS
Length:279
Mass (Da):31,775
Last modified:October 1, 1996 - v1
Checksum:iA72B39889DC74625
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti12D → G in AAT93150 (PubMed:17322287).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z72527 Genomic DNA Translation: CAA96705.1
AY693131 Genomic DNA Translation: AAT93150.1
BK006941 Genomic DNA Translation: DAA08094.1
PIRiS64007
RefSeqiNP_011510.1, NM_001180870.1

Genome annotation databases

EnsemblFungiiYGL005C; YGL005C; YGL005C
GeneIDi852879
KEGGisce:YGL005C

Similar proteinsi

Entry informationi

Entry nameiCOG7_YEAST
AccessioniPrimary (citable) accession number: P53195
Secondary accession number(s): D6VUD3, E9P921
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: May 23, 2018
This is version 126 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome VII
    Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names

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