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Protein

Uncharacterized protein BRP1

Gene

BRP1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein BRP1
Gene namesi
Name:BRP1
Ordered Locus Names:YGL007W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome VII

Organism-specific databases

SGDiS000002975. BRP1.

Pathology & Biotechi

Disruption phenotypei

Causes resistance to toxic polyamine concentrations (PubMed:15855155). Present in the 5'-UTR of plasma membrane ATPase 1 (PMA1), the ORF spans two upstream activating sequences (UAS) that are important for the expression of PMA1, and the deletion phenoytpe is attributed to down-regulation of PMA1 (PubMed:16374585).1 Publication1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002027771 – 125Uncharacterized protein BRP1Add BLAST125

Structurei

3D structure databases

ProteinModelPortaliP53194.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

OrthoDBiEOG092C5FUA.

Sequencei

Sequence statusi: Complete.

P53194-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMEKEGKKPE RHMDNILKMS IPVKSMSEVS RPGSAALGNT DAMRASLRNS
60 70 80 90 100
RRSFSGHVRL VLRLVYGFIS AVIIAGSPLR DRVCFQITGK GQAKQSDVWV
110 120
IPAMPVYVSP FQEACFVFSP SAMVT
Length:125
Mass (Da):13,790
Last modified:October 1, 1996 - v1
Checksum:i66F6E7A5C6DE3247
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z72529 Genomic DNA. Translation: CAA96707.1.
AY693239 Genomic DNA. Translation: AAT93258.1.
BK006941 Genomic DNA. Translation: DAA80299.1.
PIRiS64009.

Genome annotation databases

EnsemblFungiiYGL007W; YGL007W; YGL007W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z72529 Genomic DNA. Translation: CAA96707.1.
AY693239 Genomic DNA. Translation: AAT93258.1.
BK006941 Genomic DNA. Translation: DAA80299.1.
PIRiS64009.

3D structure databases

ProteinModelPortaliP53194.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYGL007W; YGL007W; YGL007W.

Organism-specific databases

SGDiS000002975. BRP1.

Phylogenomic databases

OrthoDBiEOG092C5FUA.

Family and domain databases

ProtoNetiSearch...

Entry informationi

Entry nameiBRP1_YEAST
AccessioniPrimary (citable) accession number: P53194
Secondary accession number(s): A0A1S0T082
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: May 10, 2017
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Caution

Was originally (PubMed:15855155) thought to function in polyamine resistance, hence the name BRP1, but this phenotype was later (PubMed:16374585) attributed to down-regulation of PMA1.2 Publications

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome VII
    Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.