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Protein

Probable family 17 glucosidase SCW11

Gene

SCW11

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Involved in cell separation.1 Publication

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei478 – 4781NucleophileBy similarity
Active sitei532 – 5321Proton donorBy similarity

GO - Molecular functioni

  • 1,3-beta-glucanosyltransferase activity Source: GO_Central
  • glucan endo-1,3-beta-D-glucosidase activity Source: SGD

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Keywords - Biological processi

Cell wall biogenesis/degradation

Enzyme and pathway databases

BioCyciYEAST:G3O-30544-MONOMER.

Protein family/group databases

CAZyiGH17. Glycoside Hydrolase Family 17.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable family 17 glucosidase SCW11 (EC:3.2.1.-)
Alternative name(s):
Soluble cell wall protein 11
Gene namesi
Name:SCW11
Ordered Locus Names:YGL028C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome VII

Organism-specific databases

EuPathDBiFungiDB:YGL028C.
SGDiS000002996. SCW11.

Subcellular locationi

  • Secretedcell wall 1 Publication

GO - Cellular componenti

  • cell surface Source: GO_Central
  • extracellular region Source: GO_Central
  • fungal-type cell wall Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Cell wall, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2020Sequence analysisAdd
BLAST
Chaini21 – 542522Probable family 17 glucosidase SCW11PRO_0000011903Add
BLAST

Proteomic databases

MaxQBiP53189.

Interactioni

Protein-protein interaction databases

BioGridi33219. 15 interactions.
DIPiDIP-1848N.
IntActiP53189. 6 interactions.
MINTiMINT-408064.

Structurei

3D structure databases

ProteinModelPortaliP53189.
SMRiP53189. Positions 291-538.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi31 – 303273Ser/Thr-richAdd
BLAST

Sequence similaritiesi

Belongs to the glycosyl hydrolase 17 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

GeneTreeiENSGT00390000008245.
HOGENOMiHOG000248356.
InParanoidiP53189.
OMAiANDGGCK.
OrthoDBiEOG092C20DF.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR000490. Glyco_hydro_17.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.
PROSITEiPS00587. GLYCOSYL_HYDROL_F17. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P53189-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MISPISFLSS LLCLTYLTSA LPILPKREVV TRVHTASTTN VVTDFYSTTT
60 70 80 90 100
EVVIAPTVEF LISDSVTFTT TLIPQGVNPT AEPTTTITKV LLKKAEMSTS
110 120 130 140 150
SQPTSTLQPS TIPQSTSSFQ AESTLQAVST QQTAMSVSAG TSEDVQQLAT
160 170 180 190 200
TSTSISSSPS PTTTSTSTQN IVSGVGEANV EGNTQSQHHS YQAAATSTLN
210 220 230 240 250
QQTSTSIASQ ESTESTNTPT SSSTSSSTSS STSSSTSSST SSSTSSSTSS
260 270 280 290 300
STSSSTSSTQ ETAATTSEGS SSSSAAITSS PKAIAYSPYN DDGSCKSADA
310 320 330 340 350
VSSDLTLIKS KGISKIRVYG TDCNSFETVQ PAAVKLGIKI NQGLYITSSG
360 370 380 390 400
VDSIDDSVTT LIQYGQTNGW DVFDFITVGN EAINNGWCSV SDLISKISSV
410 420 430 440 450
KSKLSEAGYS GQITTSEPPV SFENNPDLCK KSDIDFVGIN PHAYFDTSAS
460 470 480 490 500
AETAGTFVKG QVELIQGVCG TSNVFVTETG YPSSGIQNGG NIPSTANQIT
510 520 530 540
AVQNILNEMD LDVTILSTYN DYWKAPGDYG IEQSFGVIEY FP
Length:542
Mass (Da):56,447
Last modified:October 1, 1996 - v1
Checksum:i560CE07CA1669959
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z72550 Genomic DNA. Translation: CAA96729.1.
BK006941 Genomic DNA. Translation: DAA08071.1.
PIRiS64030.
RefSeqiNP_011487.3. NM_001180893.3.

Genome annotation databases

EnsemblFungiiYGL028C; YGL028C; YGL028C.
GeneIDi852856.
KEGGisce:YGL028C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z72550 Genomic DNA. Translation: CAA96729.1.
BK006941 Genomic DNA. Translation: DAA08071.1.
PIRiS64030.
RefSeqiNP_011487.3. NM_001180893.3.

3D structure databases

ProteinModelPortaliP53189.
SMRiP53189. Positions 291-538.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi33219. 15 interactions.
DIPiDIP-1848N.
IntActiP53189. 6 interactions.
MINTiMINT-408064.

Protein family/group databases

CAZyiGH17. Glycoside Hydrolase Family 17.

Proteomic databases

MaxQBiP53189.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYGL028C; YGL028C; YGL028C.
GeneIDi852856.
KEGGisce:YGL028C.

Organism-specific databases

EuPathDBiFungiDB:YGL028C.
SGDiS000002996. SCW11.

Phylogenomic databases

GeneTreeiENSGT00390000008245.
HOGENOMiHOG000248356.
InParanoidiP53189.
OMAiANDGGCK.
OrthoDBiEOG092C20DF.

Enzyme and pathway databases

BioCyciYEAST:G3O-30544-MONOMER.

Miscellaneous databases

PROiP53189.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR000490. Glyco_hydro_17.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.
PROSITEiPS00587. GLYCOSYL_HYDROL_F17. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSCW11_YEAST
AccessioniPrimary (citable) accession number: P53189
Secondary accession number(s): D6VUB0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: September 7, 2016
This is version 124 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 22600 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families
  3. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  4. Yeast chromosome VII
    Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.