SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P53163

- MNP1_YEAST

UniProt

P53163 - MNP1_YEAST

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
54S ribosomal protein L12, mitochondrial
Gene
MNP1, MRPL12, YGL068W
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 4 out of 5 - Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. structural constituent of ribosome Source: SGD

GO - Biological processi

  1. aerobic respiration Source: SGD
  2. translation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

BioCyciYEAST:G3O-30572-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
54S ribosomal protein L12, mitochondrial
Alternative name(s):
Mitochondrial-nucleoid protein 1
Gene namesi
Name:MNP1
Synonyms:MRPL12
Ordered Locus Names:YGL068W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome VII

Organism-specific databases

CYGDiYGL068w.
SGDiS000003036. MNP1.

Subcellular locationi

Mitochondrion 3 Publications

GO - Cellular componenti

  1. mitochondrial nucleoid Source: SGD
  2. ribosome Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei1 – 3333Mitochondrion1 Publication
Add
BLAST
Chaini34 – 19416154S ribosomal protein L12, mitochondrialUniRule annotation
PRO_0000030460Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi34 – 341N-linked (GlcNAc...) Reviewed prediction

Post-translational modificationi

N-glycosylated.UniRule annotation

Keywords - PTMi

Glycoprotein

Proteomic databases

MaxQBiP53163.
PaxDbiP53163.
PeptideAtlasiP53163.

Expressioni

Gene expression databases

GenevestigatoriP53163.

Interactioni

Subunit structurei

Component of the mitochondrial large ribosomal subunit. Mature mitochondrial ribosomes consist of a small (37S) and a large (54S) subunit. The 37S subunit contains at least 33 different proteins and 1 molecule of RNA (15S). The 54S subunit contains at least 45 different proteins and 1 molecule of RNA (21S).2 Publications

Protein-protein interaction databases

BioGridi33179. 27 interactions.
DIPiDIP-6428N.
IntActiP53163. 4 interactions.
MINTiMINT-705819.
STRINGi4932.YGL068W.

Structurei

3D structure databases

ProteinModelPortaliP53163.
SMRiP53163. Positions 139-194.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiCOG0222.
GeneTreeiENSGT00390000000190.
HOGENOMiHOG000248814.
KOiK02935.
OMAiMYCTRYC.
OrthoDBiEOG70GMV4.

Family and domain databases

Gene3Di3.30.1390.10. 1 hit.
HAMAPiMF_00368. Ribosomal_L7_L12.
InterProiIPR000206. Ribosomal_L7/12.
IPR014719. Ribosomal_L7/12_C/ClpS-like.
IPR013823. Ribosomal_L7/L12_C.
IPR008932. Ribosomal_L7/L12_oligo.
[Graphical view]
PANTHERiPTHR11809. PTHR11809. 1 hit.
PfamiPF00542. Ribosomal_L12. 1 hit.
[Graphical view]
ProDomiPD001326. Ribosomal_L7/L12_C. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF48300. SSF48300. 1 hit.
SSF54736. SSF54736. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P53163-1 [UniParc]FASTAAdd to Basket

« Hide

MSLRILAKRS SSIWMKTRVT PALISPITIT TRFNSTTTTA PSHKDDVRPV    50
DPKISKIVQD ISQLTLLETS SLINELKTVL NIPEISMPMG GFMAGAAGAG 100
AGNVPSSTGE AGSGAEEEAK PEAKTVFTVK LDSFDTKTKA KVIKEVKGLL 150
GLSLVEAKKF VEAAPKVLKE NVAKDDAEKI KKTLEDLGAK VSLE 194
Length:194
Mass (Da):20,650
Last modified:October 1, 1996 - v1
Checksum:iD7892681B778B8A9
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti34 – 341N → D AA sequence 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z72591 Genomic DNA. Translation: CAA96773.1.
BK006941 Genomic DNA. Translation: DAA08034.1.
PIRiS64075.
RefSeqiNP_011447.1. NM_001180933.1.

Genome annotation databases

EnsemblFungiiYGL068W; YGL068W; YGL068W.
GeneIDi852811.
KEGGisce:YGL068W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z72591 Genomic DNA. Translation: CAA96773.1 .
BK006941 Genomic DNA. Translation: DAA08034.1 .
PIRi S64075.
RefSeqi NP_011447.1. NM_001180933.1.

3D structure databases

ProteinModelPortali P53163.
SMRi P53163. Positions 139-194.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 33179. 27 interactions.
DIPi DIP-6428N.
IntActi P53163. 4 interactions.
MINTi MINT-705819.
STRINGi 4932.YGL068W.

Proteomic databases

MaxQBi P53163.
PaxDbi P53163.
PeptideAtlasi P53163.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YGL068W ; YGL068W ; YGL068W .
GeneIDi 852811.
KEGGi sce:YGL068W.

Organism-specific databases

CYGDi YGL068w.
SGDi S000003036. MNP1.

Phylogenomic databases

eggNOGi COG0222.
GeneTreei ENSGT00390000000190.
HOGENOMi HOG000248814.
KOi K02935.
OMAi MYCTRYC.
OrthoDBi EOG70GMV4.

Enzyme and pathway databases

BioCyci YEAST:G3O-30572-MONOMER.

Miscellaneous databases

NextBioi 972342.
PROi P53163.

Gene expression databases

Genevestigatori P53163.

Family and domain databases

Gene3Di 3.30.1390.10. 1 hit.
HAMAPi MF_00368. Ribosomal_L7_L12.
InterProi IPR000206. Ribosomal_L7/12.
IPR014719. Ribosomal_L7/12_C/ClpS-like.
IPR013823. Ribosomal_L7/L12_C.
IPR008932. Ribosomal_L7/L12_oligo.
[Graphical view ]
PANTHERi PTHR11809. PTHR11809. 1 hit.
Pfami PF00542. Ribosomal_L12. 1 hit.
[Graphical view ]
ProDomi PD001326. Ribosomal_L7/L12_C. 1 hit.
[Graphical view ] [Entries sharing at least one domain ]
SUPFAMi SSF48300. SSF48300. 1 hit.
SSF54736. SSF54736. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence analysis of 203 kilobases from Saccharomyces cerevisiae chromosome VII."
    Rieger M., Brueckner M., Schaefer M., Mueller-Auer S.
    Yeast 13:1077-1090(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. "The nucleotide sequence of Saccharomyces cerevisiae chromosome VII."
    Tettelin H., Agostoni-Carbone M.L., Albermann K., Albers M., Arroyo J., Backes U., Barreiros T., Bertani I., Bjourson A.J., Brueckner M., Bruschi C.V., Carignani G., Castagnoli L., Cerdan E., Clemente M.L., Coblenz A., Coglievina M., Coissac E.
    , Defoor E., Del Bino S., Delius H., Delneri D., de Wergifosse P., Dujon B., Durand P., Entian K.-D., Eraso P., Escribano V., Fabiani L., Fartmann B., Feroli F., Feuermann M., Frontali L., Garcia-Gonzalez M., Garcia-Saez M.I., Goffeau A., Guerreiro P., Hani J., Hansen M., Hebling U., Hernandez K., Heumann K., Hilger F., Hofmann B., Indge K.J., James C.M., Klima R., Koetter P., Kramer B., Kramer W., Lauquin G., Leuther H., Louis E.J., Maillier E., Marconi A., Martegani E., Mazon M.J., Mazzoni C., McReynolds A.D.K., Melchioretto P., Mewes H.-W., Minenkova O., Mueller-Auer S., Nawrocki A., Netter P., Neu R., Nombela C., Oliver S.G., Panzeri L., Paoluzi S., Plevani P., Portetelle D., Portillo F., Potier S., Purnelle B., Rieger M., Riles L., Rinaldi T., Robben J., Rodrigues-Pousada C., Rodriguez-Belmonte E., Rodriguez-Torres A.M., Rose M., Ruzzi M., Saliola M., Sanchez-Perez M., Schaefer B., Schaefer M., Scharfe M., Schmidheini T., Schreer A., Skala J., Souciet J.-L., Steensma H.Y., Talla E., Thierry A., Vandenbol M., van der Aart Q.J.M., Van Dyck L., Vanoni M., Verhasselt P., Voet M., Volckaert G., Wambutt R., Watson M.D., Weber N., Wedler E., Wedler H., Wipfli P., Wolf K., Wright L.F., Zaccaria P., Zimmermann M., Zollner A., Kleine K.
    Nature 387:81-84(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  3. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  4. "A 22 kDa protein specific for yeast mitochondrial nucleoids is an unidentified putative ribosomal protein encoded in open reading frame YGL068W."
    Sato H., Miyakawa I.
    Protoplasma 223:175-182(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 34-48, SUBUNIT, SUBCELLULAR LOCATION.
  5. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  6. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
  7. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
    Strain: ATCC 76625 / YPH499.
  8. "Identification and comparative analysis of the large subunit mitochondrial ribosomal proteins of Neurospora crassa."
    Gan X., Arita K., Isono S., Kitakawa M., Yoshino K., Yonezawa K., Kato A., Inoue H., Isono K.
    FEMS Microbiol. Lett. 254:157-164(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBUNIT.
  9. "Global analysis of the glycoproteome in Saccharomyces cerevisiae reveals new roles for protein glycosylation in eukaryotes."
    Kung L.A., Tao S.-C., Qian J., Smith M.G., Snyder M., Zhu H.
    Mol. Syst. Biol. 5:308-308(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS], SUBCELLULAR LOCATION.

Entry informationi

Entry nameiMNP1_YEAST
AccessioniPrimary (citable) accession number: P53163
Secondary accession number(s): D6VU73
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: June 11, 2014
This is version 110 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 6900 molecules/cell in log phase SD medium.

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families
  3. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  4. Yeast chromosome VII
    Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names

External Data

Dasty 3

Similar proteinsi