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Protein

Biogenesis of lysosome-related organelles complex 1 subunit KXD1

Gene

KXD1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting.1 Publication

Miscellaneous

Present with 1630 molecules/cell in log phase SD medium.1 Publication

GO - Biological processi

  • endosome organization Source: SGD
  • regulation of protein localization Source: SGD

Keywordsi

Biological processTransport

Enzyme and pathway databases

BioCyciYEAST:G3O-30580-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Biogenesis of lysosome-related organelles complex 1 subunit KXD1
Short name:
BLOC-1 subunit KXD1
Alternative name(s):
KxDL homolog
Gene namesi
Name:KXD1
Ordered Locus Names:YGL079W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome VII

Organism-specific databases

EuPathDBiFungiDB:YGL079W
SGDiS000003047 KXD1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Endosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002027591 – 218Biogenesis of lysosome-related organelles complex 1 subunit KXD1Add BLAST218

Proteomic databases

MaxQBiP53158
PaxDbiP53158
PRIDEiP53158

Interactioni

Subunit structurei

Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) composed of at least BLI1, BLS1, CNL1, KXD1, SNN1 and VAB2.1 Publication

Protein-protein interaction databases

BioGridi33171, 93 interactors
DIPiDIP-5247N
IntActiP53158, 7 interactors
MINTiP53158
STRINGi4932.YGL079W

Structurei

3D structure databases

ProteinModelPortaliP53158
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili142 – 192Sequence analysisAdd BLAST51

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi175 – 179KxDL5

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi16 – 64Ser-richAdd BLAST49

Sequence similaritiesi

Belongs to the KXD1 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

InParanoidiP53158
KOiK22243
OMAiINEEAHH
OrthoDBiEOG092C5F1D

Family and domain databases

InterProiView protein in InterPro
IPR019371 Uncharacterised_KxDL
PfamiView protein in Pfam
PF10241 KxDL, 1 hit

Sequencei

Sequence statusi: Complete.

P53158-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVTGISEEND DEETFSAVHS STPSINSQSY AIPITEEMSS SFHDSISTTS
60 70 80 90 100
NSSGSFDSDG SNVSDVVEQN EMDNESNVDE DLFLDNDIPQ SSNLLPTDAQ
110 120 130 140 150
DPGPIFDVSR YIFDSLKQSI DSADFSEALS LQTKTSAVIN SKSLELKQYI
160 170 180 190 200
DEMKSRLTQL QEKFENGEAT SKKIKRDLET SRKNIDYLNA ALRVDFPIEF
210
NQAREKILER RLNEDHDC
Length:218
Mass (Da):24,442
Last modified:October 1, 1996 - v1
Checksum:i61541771FBEC8F8C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z72601 Genomic DNA Translation: CAA96784.1
AY558485 Genomic DNA Translation: AAS56811.1
BK006941 Genomic DNA Translation: DAA08026.1
PIRiS64086
RefSeqiNP_011436.1, NM_001180944.1

Genome annotation databases

EnsemblFungiiYGL079W; YGL079W; YGL079W
GeneIDi852801
KEGGisce:YGL079W

Similar proteinsi

Entry informationi

Entry nameiKXD1_YEAST
AccessioniPrimary (citable) accession number: P53158
Secondary accession number(s): D6VU65
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: May 23, 2018
This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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