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P53147

- TOS8_YEAST

UniProt

P53147 - TOS8_YEAST

Protein

Homeobox protein TOS8

Gene

TOS8

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 116 (01 Oct 2014)
      Sequence version 1 (01 Oct 1996)
      Previous versions | rss
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    Functioni

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    DNA bindingi194 – 25663Homeobox; TALE-typePROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. chromatin binding Source: SGD
    2. sequence-specific DNA binding Source: InterPro
    3. sequence-specific DNA binding transcription factor activity Source: InterPro

    Keywords - Ligandi

    DNA-binding

    Enzyme and pathway databases

    BioCyciYEAST:G3O-30596-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Homeobox protein TOS8
    Alternative name(s):
    Target of SBF 8
    Gene namesi
    Name:TOS8
    Ordered Locus Names:YGL096W
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome VII

    Organism-specific databases

    CYGDiYGL096w.
    SGDiS000003064. TOS8.

    Subcellular locationi

    Nucleus Curated

    GO - Cellular componenti

    1. nuclear chromatin Source: SGD

    Keywords - Cellular componenti

    Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 276276Homeobox protein TOS8PRO_0000049400Add
    BLAST

    Expressioni

    Gene expression databases

    GenevestigatoriP53147.

    Interactioni

    Protein-protein interaction databases

    BioGridi33154. 22 interactions.
    DIPiDIP-980N.
    IntActiP53147. 3 interactions.
    MINTiMINT-397623.
    STRINGi4932.YGL096W.

    Structurei

    3D structure databases

    ProteinModelPortaliP53147.
    SMRiP53147. Positions 201-251.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the TALE/CUP9 homeobox family.Curated
    Contains 1 homeobox DNA-binding domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Homeobox

    Phylogenomic databases

    eggNOGiNOG259970.
    GeneTreeiENSGT00680000099964.
    OrthoDBiEOG7BP8FC.

    Family and domain databases

    Gene3Di1.10.10.60. 1 hit.
    InterProiIPR001356. Homeobox_dom.
    IPR008422. Homeobox_KN_domain.
    IPR009057. Homeodomain-like.
    [Graphical view]
    PfamiPF05920. Homeobox_KN. 1 hit.
    [Graphical view]
    SMARTiSM00389. HOX. 1 hit.
    [Graphical view]
    SUPFAMiSSF46689. SSF46689. 1 hit.
    PROSITEiPS00027. HOMEOBOX_1. 1 hit.
    PS50071. HOMEOBOX_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P53147-1 [UniParc]FASTAAdd to Basket

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    MGTSIVNLNQ KIELPPIQVL FESLNRENET KPHFEERRLY QPNPSFVPRT    50
    NIAVGSPVNP VPVSSPVFFI GPSPQRSIQN HNAIMTQNIR QYPVIYNNNR 100
    EVISTGERNY IITVGGPPVT SSQPEYEHIS TPNFYQEQRL AQPHPVNESM 150
    MIGGYTNPQP ISISRGKMLS GNISTNSVRG SNNGYSAKEK KHKAHGKRSN 200
    LPKATVSILN KWLHEHVNNP YPTVQEKREL LAKTGLTKLQ ISNWFINARR 250
    RKIFSGQNDA NNFRRKFSSS TNLAKF 276
    Length:276
    Mass (Da):31,257
    Last modified:October 1, 1996 - v1
    Checksum:i113BE5C51A8D7FFA
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z72618 Genomic DNA. Translation: CAA96802.1.
    AY558496 Genomic DNA. Translation: AAS56822.1.
    BK006941 Genomic DNA. Translation: DAA08010.1.
    PIRiS64103.
    RefSeqiNP_011419.1. NM_001180961.1.

    Genome annotation databases

    EnsemblFungiiYGL096W; YGL096W; YGL096W.
    GeneIDi852783.
    KEGGisce:YGL096W.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z72618 Genomic DNA. Translation: CAA96802.1 .
    AY558496 Genomic DNA. Translation: AAS56822.1 .
    BK006941 Genomic DNA. Translation: DAA08010.1 .
    PIRi S64103.
    RefSeqi NP_011419.1. NM_001180961.1.

    3D structure databases

    ProteinModelPortali P53147.
    SMRi P53147. Positions 201-251.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 33154. 22 interactions.
    DIPi DIP-980N.
    IntActi P53147. 3 interactions.
    MINTi MINT-397623.
    STRINGi 4932.YGL096W.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YGL096W ; YGL096W ; YGL096W .
    GeneIDi 852783.
    KEGGi sce:YGL096W.

    Organism-specific databases

    CYGDi YGL096w.
    SGDi S000003064. TOS8.

    Phylogenomic databases

    eggNOGi NOG259970.
    GeneTreei ENSGT00680000099964.
    OrthoDBi EOG7BP8FC.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-30596-MONOMER.

    Miscellaneous databases

    NextBioi 972268.

    Gene expression databases

    Genevestigatori P53147.

    Family and domain databases

    Gene3Di 1.10.10.60. 1 hit.
    InterProi IPR001356. Homeobox_dom.
    IPR008422. Homeobox_KN_domain.
    IPR009057. Homeodomain-like.
    [Graphical view ]
    Pfami PF05920. Homeobox_KN. 1 hit.
    [Graphical view ]
    SMARTi SM00389. HOX. 1 hit.
    [Graphical view ]
    SUPFAMi SSF46689. SSF46689. 1 hit.
    PROSITEi PS00027. HOMEOBOX_1. 1 hit.
    PS50071. HOMEOBOX_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequence analysis of 203 kilobases from Saccharomyces cerevisiae chromosome VII."
      Rieger M., Brueckner M., Schaefer M., Mueller-Auer S.
      Yeast 13:1077-1090(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    2. "The nucleotide sequence of Saccharomyces cerevisiae chromosome VII."
      Tettelin H., Agostoni-Carbone M.L., Albermann K., Albers M., Arroyo J., Backes U., Barreiros T., Bertani I., Bjourson A.J., Brueckner M., Bruschi C.V., Carignani G., Castagnoli L., Cerdan E., Clemente M.L., Coblenz A., Coglievina M., Coissac E.
      , Defoor E., Del Bino S., Delius H., Delneri D., de Wergifosse P., Dujon B., Durand P., Entian K.-D., Eraso P., Escribano V., Fabiani L., Fartmann B., Feroli F., Feuermann M., Frontali L., Garcia-Gonzalez M., Garcia-Saez M.I., Goffeau A., Guerreiro P., Hani J., Hansen M., Hebling U., Hernandez K., Heumann K., Hilger F., Hofmann B., Indge K.J., James C.M., Klima R., Koetter P., Kramer B., Kramer W., Lauquin G., Leuther H., Louis E.J., Maillier E., Marconi A., Martegani E., Mazon M.J., Mazzoni C., McReynolds A.D.K., Melchioretto P., Mewes H.-W., Minenkova O., Mueller-Auer S., Nawrocki A., Netter P., Neu R., Nombela C., Oliver S.G., Panzeri L., Paoluzi S., Plevani P., Portetelle D., Portillo F., Potier S., Purnelle B., Rieger M., Riles L., Rinaldi T., Robben J., Rodrigues-Pousada C., Rodriguez-Belmonte E., Rodriguez-Torres A.M., Rose M., Ruzzi M., Saliola M., Sanchez-Perez M., Schaefer B., Schaefer M., Scharfe M., Schmidheini T., Schreer A., Skala J., Souciet J.-L., Steensma H.Y., Talla E., Thierry A., Vandenbol M., van der Aart Q.J.M., Van Dyck L., Vanoni M., Verhasselt P., Voet M., Volckaert G., Wambutt R., Watson M.D., Weber N., Wedler E., Wedler H., Wipfli P., Wolf K., Wright L.F., Zaccaria P., Zimmermann M., Zollner A., Kleine K.
      Nature 387:81-84(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    3. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    4. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 204508 / S288c.

    Entry informationi

    Entry nameiTOS8_YEAST
    AccessioniPrimary (citable) accession number: P53147
    Secondary accession number(s): D6VU49
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 1, 1996
    Last sequence update: October 1, 1996
    Last modified: October 1, 2014
    This is version 116 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    3. Yeast chromosome VII
      Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names

    External Data

    Dasty 3