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P53147

- TOS8_YEAST

UniProt

P53147 - TOS8_YEAST

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Protein
Homeobox protein TOS8
Gene
TOS8, YGL096W
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi194 – 25663Homeobox; TALE-type
Add
BLAST

GO - Molecular functioni

  1. chromatin binding Source: SGD
  2. sequence-specific DNA binding Source: InterPro
  3. sequence-specific DNA binding transcription factor activity Source: InterPro
Complete GO annotation...

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciYEAST:G3O-30596-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Homeobox protein TOS8
Alternative name(s):
Target of SBF 8
Gene namesi
Name:TOS8
Ordered Locus Names:YGL096W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome VII

Organism-specific databases

CYGDiYGL096w.
SGDiS000003064. TOS8.

Subcellular locationi

Nucleus Inferred

GO - Cellular componenti

  1. nuclear chromatin Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 276276Homeobox protein TOS8
PRO_0000049400Add
BLAST

Expressioni

Gene expression databases

GenevestigatoriP53147.

Interactioni

Protein-protein interaction databases

BioGridi33154. 22 interactions.
DIPiDIP-980N.
IntActiP53147. 3 interactions.
MINTiMINT-397623.
STRINGi4932.YGL096W.

Structurei

3D structure databases

ProteinModelPortaliP53147.
SMRiP53147. Positions 201-251.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Homeobox

Phylogenomic databases

eggNOGiNOG259970.
GeneTreeiENSGT00680000099964.
OrthoDBiEOG7BP8FC.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR001356. Homeobox_dom.
IPR008422. Homeobox_KN_domain.
IPR009057. Homeodomain-like.
[Graphical view]
PfamiPF05920. Homeobox_KN. 1 hit.
[Graphical view]
SMARTiSM00389. HOX. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P53147-1 [UniParc]FASTAAdd to Basket

« Hide

MGTSIVNLNQ KIELPPIQVL FESLNRENET KPHFEERRLY QPNPSFVPRT    50
NIAVGSPVNP VPVSSPVFFI GPSPQRSIQN HNAIMTQNIR QYPVIYNNNR 100
EVISTGERNY IITVGGPPVT SSQPEYEHIS TPNFYQEQRL AQPHPVNESM 150
MIGGYTNPQP ISISRGKMLS GNISTNSVRG SNNGYSAKEK KHKAHGKRSN 200
LPKATVSILN KWLHEHVNNP YPTVQEKREL LAKTGLTKLQ ISNWFINARR 250
RKIFSGQNDA NNFRRKFSSS TNLAKF 276
Length:276
Mass (Da):31,257
Last modified:October 1, 1996 - v1
Checksum:i113BE5C51A8D7FFA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z72618 Genomic DNA. Translation: CAA96802.1.
AY558496 Genomic DNA. Translation: AAS56822.1.
BK006941 Genomic DNA. Translation: DAA08010.1.
PIRiS64103.
RefSeqiNP_011419.1. NM_001180961.1.

Genome annotation databases

EnsemblFungiiYGL096W; YGL096W; YGL096W.
GeneIDi852783.
KEGGisce:YGL096W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z72618 Genomic DNA. Translation: CAA96802.1 .
AY558496 Genomic DNA. Translation: AAS56822.1 .
BK006941 Genomic DNA. Translation: DAA08010.1 .
PIRi S64103.
RefSeqi NP_011419.1. NM_001180961.1.

3D structure databases

ProteinModelPortali P53147.
SMRi P53147. Positions 201-251.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 33154. 22 interactions.
DIPi DIP-980N.
IntActi P53147. 3 interactions.
MINTi MINT-397623.
STRINGi 4932.YGL096W.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YGL096W ; YGL096W ; YGL096W .
GeneIDi 852783.
KEGGi sce:YGL096W.

Organism-specific databases

CYGDi YGL096w.
SGDi S000003064. TOS8.

Phylogenomic databases

eggNOGi NOG259970.
GeneTreei ENSGT00680000099964.
OrthoDBi EOG7BP8FC.

Enzyme and pathway databases

BioCyci YEAST:G3O-30596-MONOMER.

Miscellaneous databases

NextBioi 972268.

Gene expression databases

Genevestigatori P53147.

Family and domain databases

Gene3Di 1.10.10.60. 1 hit.
InterProi IPR001356. Homeobox_dom.
IPR008422. Homeobox_KN_domain.
IPR009057. Homeodomain-like.
[Graphical view ]
Pfami PF05920. Homeobox_KN. 1 hit.
[Graphical view ]
SMARTi SM00389. HOX. 1 hit.
[Graphical view ]
SUPFAMi SSF46689. SSF46689. 1 hit.
PROSITEi PS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence analysis of 203 kilobases from Saccharomyces cerevisiae chromosome VII."
    Rieger M., Brueckner M., Schaefer M., Mueller-Auer S.
    Yeast 13:1077-1090(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. "The nucleotide sequence of Saccharomyces cerevisiae chromosome VII."
    Tettelin H., Agostoni-Carbone M.L., Albermann K., Albers M., Arroyo J., Backes U., Barreiros T., Bertani I., Bjourson A.J., Brueckner M., Bruschi C.V., Carignani G., Castagnoli L., Cerdan E., Clemente M.L., Coblenz A., Coglievina M., Coissac E.
    , Defoor E., Del Bino S., Delius H., Delneri D., de Wergifosse P., Dujon B., Durand P., Entian K.-D., Eraso P., Escribano V., Fabiani L., Fartmann B., Feroli F., Feuermann M., Frontali L., Garcia-Gonzalez M., Garcia-Saez M.I., Goffeau A., Guerreiro P., Hani J., Hansen M., Hebling U., Hernandez K., Heumann K., Hilger F., Hofmann B., Indge K.J., James C.M., Klima R., Koetter P., Kramer B., Kramer W., Lauquin G., Leuther H., Louis E.J., Maillier E., Marconi A., Martegani E., Mazon M.J., Mazzoni C., McReynolds A.D.K., Melchioretto P., Mewes H.-W., Minenkova O., Mueller-Auer S., Nawrocki A., Netter P., Neu R., Nombela C., Oliver S.G., Panzeri L., Paoluzi S., Plevani P., Portetelle D., Portillo F., Potier S., Purnelle B., Rieger M., Riles L., Rinaldi T., Robben J., Rodrigues-Pousada C., Rodriguez-Belmonte E., Rodriguez-Torres A.M., Rose M., Ruzzi M., Saliola M., Sanchez-Perez M., Schaefer B., Schaefer M., Scharfe M., Schmidheini T., Schreer A., Skala J., Souciet J.-L., Steensma H.Y., Talla E., Thierry A., Vandenbol M., van der Aart Q.J.M., Van Dyck L., Vanoni M., Verhasselt P., Voet M., Volckaert G., Wambutt R., Watson M.D., Weber N., Wedler E., Wedler H., Wipfli P., Wolf K., Wright L.F., Zaccaria P., Zimmermann M., Zollner A., Kleine K.
    Nature 387:81-84(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  3. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  4. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.

Entry informationi

Entry nameiTOS8_YEAST
AccessioniPrimary (citable) accession number: P53147
Secondary accession number(s): D6VU49
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: May 14, 2014
This is version 115 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome VII
    Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names

External Data

Dasty 3

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