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P53139

- YGK8_YEAST

UniProt

P53139 - YGK8_YEAST

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Protein

Uncharacterized protein YGL108C

Gene

YGL108C

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

BioCyciYEAST:G3O-30607-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein YGL108C
Gene namesi
Ordered Locus Names:YGL108C
ORF Names:G3070
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome VII

Organism-specific databases

CYGDiYGL108c.
SGDiS000003076. YGL108C.

Subcellular locationi

Cell membrane 1 Publication; Lipid-anchor 1 Publication

GO - Cellular componenti

  1. plasma membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11RemovedSequence Analysis
Chaini2 – 140139Uncharacterized protein YGL108CPRO_0000202751Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Lipidationi2 – 21N-myristoyl glycineSequence Analysis
Lipidationi4 – 41S-palmitoyl cysteineCurated

Post-translational modificationi

Myristoylated.1 Publication
The N-myristoylated protein is further palmitoylated by ERF2, PFA4 and slightly by PFA5, but not by PFA3.2 Publications

Keywords - PTMi

Lipoprotein, Myristate, Palmitate

Proteomic databases

MaxQBiP53139.
PaxDbiP53139.

Expressioni

Gene expression databases

GenevestigatoriP53139.

Interactioni

Protein-protein interaction databases

BioGridi33142. 18 interactions.
IntActiP53139. 11 interactions.
MINTiMINT-2493356.
STRINGi4932.YGL108C.

Structurei

3D structure databases

ProteinModelPortaliP53139.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi41 – 499Poly-Lys

Sequence similaritiesi

To S.pombe new13.Curated

Phylogenomic databases

eggNOGiNOG272727.
HOGENOMiHOG000142362.
InParanoidiP53139.
OMAiERENMIY.
OrthoDBiEOG718KS0.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P53139-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MGLCGSKTQP MPSQTTTVAT KARTKPINRD TVKSKQELRH KEKKDKKKKT
60 70 80 90 100
QLKSTTVPVV QRKEGSKLTD TSDPSKNKVS PKEAARLAAE KRFQETNEKY
110 120 130 140
NKGELGKKLA QERAKSHKTR LMEEAEKKHA ERERENMIYD
Length:140
Mass (Da):16,037
Last modified:October 1, 1996 - v1
Checksum:i89C6AEC296CA9E57
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X97644 Genomic DNA. Translation: CAA66244.1.
Z72631 Genomic DNA. Translation: CAA96816.1.
BK006941 Genomic DNA. Translation: DAA07999.1.
PIRiS64116.
RefSeqiNP_011407.3. NM_001180973.3.

Genome annotation databases

EnsemblFungiiYGL108C; YGL108C; YGL108C.
GeneIDi852770.
KEGGisce:YGL108C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X97644 Genomic DNA. Translation: CAA66244.1 .
Z72631 Genomic DNA. Translation: CAA96816.1 .
BK006941 Genomic DNA. Translation: DAA07999.1 .
PIRi S64116.
RefSeqi NP_011407.3. NM_001180973.3.

3D structure databases

ProteinModelPortali P53139.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 33142. 18 interactions.
IntActi P53139. 11 interactions.
MINTi MINT-2493356.
STRINGi 4932.YGL108C.

Proteomic databases

MaxQBi P53139.
PaxDbi P53139.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YGL108C ; YGL108C ; YGL108C .
GeneIDi 852770.
KEGGi sce:YGL108C.

Organism-specific databases

CYGDi YGL108c.
SGDi S000003076. YGL108C.

Phylogenomic databases

eggNOGi NOG272727.
HOGENOMi HOG000142362.
InParanoidi P53139.
OMAi ERENMIY.
OrthoDBi EOG718KS0.

Enzyme and pathway databases

BioCyci YEAST:G3O-30607-MONOMER.

Miscellaneous databases

NextBioi 972233.

Gene expression databases

Genevestigatori P53139.

Family and domain databases

ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The genes encoding the transcription factor yTAFII60, the G4p1 protein and a putative glucose transporter are contained in a 12.3 kb DNA fragment on the left arm of Saccharomyces cerevisiae chromosome VII."
    Paoluzi S., Minenkova O., Castagnoli L.
    Yeast 13:85-91(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "The nucleotide sequence of Saccharomyces cerevisiae chromosome VII."
    Tettelin H., Agostoni-Carbone M.L., Albermann K., Albers M., Arroyo J., Backes U., Barreiros T., Bertani I., Bjourson A.J., Brueckner M., Bruschi C.V., Carignani G., Castagnoli L., Cerdan E., Clemente M.L., Coblenz A., Coglievina M., Coissac E.
    , Defoor E., Del Bino S., Delius H., Delneri D., de Wergifosse P., Dujon B., Durand P., Entian K.-D., Eraso P., Escribano V., Fabiani L., Fartmann B., Feroli F., Feuermann M., Frontali L., Garcia-Gonzalez M., Garcia-Saez M.I., Goffeau A., Guerreiro P., Hani J., Hansen M., Hebling U., Hernandez K., Heumann K., Hilger F., Hofmann B., Indge K.J., James C.M., Klima R., Koetter P., Kramer B., Kramer W., Lauquin G., Leuther H., Louis E.J., Maillier E., Marconi A., Martegani E., Mazon M.J., Mazzoni C., McReynolds A.D.K., Melchioretto P., Mewes H.-W., Minenkova O., Mueller-Auer S., Nawrocki A., Netter P., Neu R., Nombela C., Oliver S.G., Panzeri L., Paoluzi S., Plevani P., Portetelle D., Portillo F., Potier S., Purnelle B., Rieger M., Riles L., Rinaldi T., Robben J., Rodrigues-Pousada C., Rodriguez-Belmonte E., Rodriguez-Torres A.M., Rose M., Ruzzi M., Saliola M., Sanchez-Perez M., Schaefer B., Schaefer M., Scharfe M., Schmidheini T., Schreer A., Skala J., Souciet J.-L., Steensma H.Y., Talla E., Thierry A., Vandenbol M., van der Aart Q.J.M., Van Dyck L., Vanoni M., Verhasselt P., Voet M., Volckaert G., Wambutt R., Watson M.D., Weber N., Wedler E., Wedler H., Wipfli P., Wolf K., Wright L.F., Zaccaria P., Zimmermann M., Zollner A., Kleine K.
    Nature 387:81-84(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  3. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  4. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  5. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
  6. Cited for: PALMITOYLATION.
  7. "Molecular recognition of the palmitoylation substrate Vac8 by its palmitoyltransferase Pfa3."
    Nadolski M.J., Linder M.E.
    J. Biol. Chem. 284:17720-17730(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: MYRISTOYLATION, PALMITOYLATION BY ERF2; PFA4 AND PFA5.

Entry informationi

Entry nameiYGK8_YEAST
AccessioniPrimary (citable) accession number: P53139
Secondary accession number(s): D6VU38
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: October 29, 2014
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 2430 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome VII
    Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names

External Data

Dasty 3