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Protein

CUE domain-containing protein 3

Gene

CUE3

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • ubiquitin binding Source: SGD

Enzyme and pathway databases

BioCyciYEAST:G3O-30608-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
CUE domain-containing protein 3
Alternative name(s):
Coupling of ubiquitin conjugation to ER degradation protein 3
Gene namesi
Name:CUE3
Ordered Locus Names:YGL110C
ORF Names:G3060
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome VII

Organism-specific databases

EuPathDBiFungiDB:YGL110C.
SGDiS000003078. CUE3.

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002027491 – 624CUE domain-containing protein 3Add BLAST624

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei377PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiP53137.
PRIDEiP53137.

PTM databases

iPTMnetiP53137.

Interactioni

GO - Molecular functioni

  • ubiquitin binding Source: SGD

Protein-protein interaction databases

BioGridi33141. 104 interactors.
DIPiDIP-5379N.
IntActiP53137. 1 interactor.
MINTiMINT-508632.

Structurei

3D structure databases

ProteinModelPortaliP53137.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini316 – 359CUEPROSITE-ProRule annotationAdd BLAST44

Phylogenomic databases

HOGENOMiHOG000248413.
InParanoidiP53137.
OMAiEKDPVVW.
OrthoDBiEOG092C0ZCK.

Family and domain databases

InterProiView protein in InterPro
IPR003892. CUE.
PfamiView protein in Pfam
PF02845. CUE. 1 hit.
SMARTiView protein in SMART
SM00546. CUE. 1 hit.
PROSITEiView protein in PROSITE
PS51140. CUE. 1 hit.

Sequencei

Sequence statusi: Complete.

P53137-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSRYNRVIE INGGNADISL PIVKFPPFKL RAQLIEKDPV VWLHLIETYV
60 70 80 90 100
TYFEYLMQGA NVELLDESTL DHLRLFLRTY LHEIADEEGK LLSLGINHDV
110 120 130 140 150
SEQLYLLKGW IFSLIKKCGL LHLQIFGDSL WNLIKVYVRR NPDSIRGLID
160 170 180 190 200
GSLKPRINTQ RVQLDKSYQV QQHLKQLIES GKFKRIDLRC VEDLLSAKSM
210 220 230 240 250
QPNKFAENFF TANWIEILEA LWAKGQGRGH KEARELIIIS LFSVSADRLL
260 270 280 290 300
KITKELGISN FETLALYPLL GTMLINEGVH KRLPDLKSKL LFLNLGGLSM
310 320 330 340 350
DEGDHMSYPT SSGTEVNEEQ LSALMELFPQ FSKYQLSQTL LAYDNNIELV
360 370 380 390 400
TNKIFEDPTI IEAFSREPAE EEVEPVSDGD NASFTEELSI LDRGDSSKNK
410 420 430 440 450
ELDKKIISEG VPDELRNKTL TRALKLLYEA DEDERDDTYD EADVNRSDPS
460 470 480 490 500
KRIGLQEDEE SYDTKDDSNE VRQDHNYHIV EAYLWNLLKE DPKLFERSKR
510 520 530 540 550
GTKVRKTMKE MTSWSDEKIE GWCRMLERSP TRARLLEKKF MFKGNSKTGK
560 570 580 590 600
TSYVHNRDSQ NDGNVVKEQA KQKKSENIKK HEPQSTEQKK RQHAKNEKRK
610 620
GARANHNRKK GHDKKLARAG NNAI
Length:624
Mass (Da):72,043
Last modified:October 1, 1996 - v1
Checksum:i9A1F679562A367E3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X97644 Genomic DNA. Translation: CAA66242.1.
Z72632 Genomic DNA. Translation: CAA96817.1.
BK006941 Genomic DNA. Translation: DAA07998.1.
PIRiS64118.
RefSeqiNP_011405.1. NM_001180975.1.

Genome annotation databases

EnsemblFungiiYGL110C; YGL110C; YGL110C.
GeneIDi852768.
KEGGisce:YGL110C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X97644 Genomic DNA. Translation: CAA66242.1.
Z72632 Genomic DNA. Translation: CAA96817.1.
BK006941 Genomic DNA. Translation: DAA07998.1.
PIRiS64118.
RefSeqiNP_011405.1. NM_001180975.1.

3D structure databases

ProteinModelPortaliP53137.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi33141. 104 interactors.
DIPiDIP-5379N.
IntActiP53137. 1 interactor.
MINTiMINT-508632.

PTM databases

iPTMnetiP53137.

Proteomic databases

MaxQBiP53137.
PRIDEiP53137.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYGL110C; YGL110C; YGL110C.
GeneIDi852768.
KEGGisce:YGL110C.

Organism-specific databases

EuPathDBiFungiDB:YGL110C.
SGDiS000003078. CUE3.

Phylogenomic databases

HOGENOMiHOG000248413.
InParanoidiP53137.
OMAiEKDPVVW.
OrthoDBiEOG092C0ZCK.

Enzyme and pathway databases

BioCyciYEAST:G3O-30608-MONOMER.

Miscellaneous databases

PROiP53137.

Family and domain databases

InterProiView protein in InterPro
IPR003892. CUE.
PfamiView protein in Pfam
PF02845. CUE. 1 hit.
SMARTiView protein in SMART
SM00546. CUE. 1 hit.
PROSITEiView protein in PROSITE
PS51140. CUE. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiCUE3_YEAST
AccessioniPrimary (citable) accession number: P53137
Secondary accession number(s): D6VU37
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: March 15, 2017
This is version 111 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 6300 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome VII
    Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.