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P53137 (CUE3_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
CUE domain-containing protein 3
Alternative name(s):
Coupling of ubiquitin conjugation to ER degradation protein 3
Gene names
Name:CUE3
Ordered Locus Names:YGL110C
ORF Names:G3060
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length624 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Cytoplasm Ref.4.

Miscellaneous

Present with 6300 molecules/cell in log phase SD medium. Ref.5

Sequence similarities

Contains 1 CUE domain.

Ontologies

Keywords
   Cellular componentCytoplasm
   PTMPhosphoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular componentcytoplasm

Inferred from direct assay Ref.4. Source: SGD

   Molecular functionubiquitin binding

Inferred from direct assay. Source: SGD

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 624624CUE domain-containing protein 3
PRO_0000202749

Regions

Domain316 – 35944CUE

Amino acid modifications

Modified residue3831Phosphoserine Ref.6

Sequences

Sequence LengthMass (Da)Tools
P53137 [UniParc].

Last modified October 1, 1996. Version 1.
Checksum: 9A1F679562A367E3

FASTA62472,043
        10         20         30         40         50         60 
MLSRYNRVIE INGGNADISL PIVKFPPFKL RAQLIEKDPV VWLHLIETYV TYFEYLMQGA 

        70         80         90        100        110        120 
NVELLDESTL DHLRLFLRTY LHEIADEEGK LLSLGINHDV SEQLYLLKGW IFSLIKKCGL 

       130        140        150        160        170        180 
LHLQIFGDSL WNLIKVYVRR NPDSIRGLID GSLKPRINTQ RVQLDKSYQV QQHLKQLIES 

       190        200        210        220        230        240 
GKFKRIDLRC VEDLLSAKSM QPNKFAENFF TANWIEILEA LWAKGQGRGH KEARELIIIS 

       250        260        270        280        290        300 
LFSVSADRLL KITKELGISN FETLALYPLL GTMLINEGVH KRLPDLKSKL LFLNLGGLSM 

       310        320        330        340        350        360 
DEGDHMSYPT SSGTEVNEEQ LSALMELFPQ FSKYQLSQTL LAYDNNIELV TNKIFEDPTI 

       370        380        390        400        410        420 
IEAFSREPAE EEVEPVSDGD NASFTEELSI LDRGDSSKNK ELDKKIISEG VPDELRNKTL 

       430        440        450        460        470        480 
TRALKLLYEA DEDERDDTYD EADVNRSDPS KRIGLQEDEE SYDTKDDSNE VRQDHNYHIV 

       490        500        510        520        530        540 
EAYLWNLLKE DPKLFERSKR GTKVRKTMKE MTSWSDEKIE GWCRMLERSP TRARLLEKKF 

       550        560        570        580        590        600 
MFKGNSKTGK TSYVHNRDSQ NDGNVVKEQA KQKKSENIKK HEPQSTEQKK RQHAKNEKRK 

       610        620 
GARANHNRKK GHDKKLARAG NNAI

« Hide

References

« Hide 'large scale' references
[1]"The genes encoding the transcription factor yTAFII60, the G4p1 protein and a putative glucose transporter are contained in a 12.3 kb DNA fragment on the left arm of Saccharomyces cerevisiae chromosome VII."
Paoluzi S., Minenkova O., Castagnoli L.
Yeast 13:85-91(1997) [PubMed: 9046090] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"The nucleotide sequence of Saccharomyces cerevisiae chromosome VII."
Tettelin H., Agostoni-Carbone M.L., Albermann K., Albers M., Arroyo J., Backes U., Barreiros T., Bertani I., Bjourson A.J., Brueckner M., Bruschi C.V., Carignani G., Castagnoli L., Cerdan E., Clemente M.L., Coblenz A., Coglievina M., Coissac E. expand/collapse author list , Defoor E., Del Bino S., Delius H., Delneri D., de Wergifosse P., Dujon B., Durand P., Entian K.-D., Eraso P., Escribano V., Fabiani L., Fartmann B., Feroli F., Feuermann M., Frontali L., Garcia-Gonzalez M., Garcia-Saez M.I., Goffeau A., Guerreiro P., Hani J., Hansen M., Hebling U., Hernandez K., Heumann K., Hilger F., Hofmann B., Indge K.J., James C.M., Klima R., Koetter P., Kramer B., Kramer W., Lauquin G., Leuther H., Louis E.J., Maillier E., Marconi A., Martegani E., Mazon M.J., Mazzoni C., McReynolds A.D.K., Melchioretto P., Mewes H.-W., Minenkova O., Mueller-Auer S., Nawrocki A., Netter P., Neu R., Nombela C., Oliver S.G., Panzeri L., Paoluzi S., Plevani P., Portetelle D., Portillo F., Potier S., Purnelle B., Rieger M., Riles L., Rinaldi T., Robben J., Rodrigues-Pousada C., Rodriguez-Belmonte E., Rodriguez-Torres A.M., Rose M., Ruzzi M., Saliola M., Sanchez-Perez M., Schaefer B., Schaefer M., Scharfe M., Schmidheini T., Schreer A., Skala J., Souciet J.-L., Steensma H.Y., Talla E., Thierry A., Vandenbol M., van der Aart Q.J.M., Van Dyck L., Vanoni M., Verhasselt P., Voet M., Volckaert G., Wambutt R., Watson M.D., Weber N., Wedler E., Wedler H., Wipfli P., Wolf K., Wright L.F., Zaccaria P., Zimmermann M., Zollner A., Kleine K.
Nature 387:81-84(1997) [PubMed: 9169869] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[4]"Global analysis of protein localization in budding yeast."
Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K.
Nature 425:686-691(2003) [PubMed: 14562095] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[5]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed: 14562106] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[6]"A multidimensional chromatography technology for in-depth phosphoproteome analysis."
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.
Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed: 18407956] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-383, MASS SPECTROMETRY.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		X97644 Genomic DNA. Translation: CAA66242.1.
Z72632 Genomic DNA. Translation: CAA96817.1.
BK006941 Genomic DNA. Translation: DAA07998.1.
PIRS64118.
RefSeqNP_011405.1. NM_001180975.1.

3D structure databases

ProteinModelPortalP53137.
SMRP53137. Positions 315-363.
ModBaseSearch...

Protein-protein interaction databases

DIPDIP-5379N.
MINTMINT-508632.
STRINGP53137.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYGL110C; YGL110C; YGL110C.
GeneID852768.
KEGGsce:YGL110C.
NMPDRfig|4932.3.peg.2510.

Organism-specific databases

CYGDYGL110c.
SGDS000003078. CUE3.

Phylogenomic databases

eggNOGfuNOG07901.
GeneTreeEFGT00050000000584.
HOGENOMHBG396371.
OMAARNEKNK.
OrthoDBEOG4P5PJX.

Gene expression databases

ArrayExpressP53137.
GenevestigatorP53137.
GermOnlineYGL110C. Saccharomyces cerevisiae.

Family and domain databases

InterProIPR003892. CUE.
[Graphical view]
PfamPF02845. CUE. 1 hit.
[Graphical view]
SMARTSM00546. CUE. 1 hit.
[Graphical view]
PROSITEPS51140. CUE. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio972230.

Entry information

Entry nameCUE3_YEAST
AccessionPrimary (citable) accession number: P53137
Secondary accession number(s): D6VU37
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: December 14, 2011
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

Yeast chromosome VII

Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents