ID   YGL4_YEAST              Reviewed;         725 AA.
AC   P53134; D6VU33;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   24-JAN-2024, entry version 144.
DE   RecName: Full=Putative oligopeptide transporter YGL114W;
GN   OrderedLocusNames=YGL114W;
OS   Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=559292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=9169869;
RA   Tettelin H., Agostoni-Carbone M.L., Albermann K., Albers M., Arroyo J.,
RA   Backes U., Barreiros T., Bertani I., Bjourson A.J., Brueckner M.,
RA   Bruschi C.V., Carignani G., Castagnoli L., Cerdan E., Clemente M.L.,
RA   Coblenz A., Coglievina M., Coissac E., Defoor E., Del Bino S., Delius H.,
RA   Delneri D., de Wergifosse P., Dujon B., Durand P., Entian K.-D., Eraso P.,
RA   Escribano V., Fabiani L., Fartmann B., Feroli F., Feuermann M.,
RA   Frontali L., Garcia-Gonzalez M., Garcia-Saez M.I., Goffeau A.,
RA   Guerreiro P., Hani J., Hansen M., Hebling U., Hernandez K., Heumann K.,
RA   Hilger F., Hofmann B., Indge K.J., James C.M., Klima R., Koetter P.,
RA   Kramer B., Kramer W., Lauquin G., Leuther H., Louis E.J., Maillier E.,
RA   Marconi A., Martegani E., Mazon M.J., Mazzoni C., McReynolds A.D.K.,
RA   Melchioretto P., Mewes H.-W., Minenkova O., Mueller-Auer S., Nawrocki A.,
RA   Netter P., Neu R., Nombela C., Oliver S.G., Panzeri L., Paoluzi S.,
RA   Plevani P., Portetelle D., Portillo F., Potier S., Purnelle B., Rieger M.,
RA   Riles L., Rinaldi T., Robben J., Rodrigues-Pousada C.,
RA   Rodriguez-Belmonte E., Rodriguez-Torres A.M., Rose M., Ruzzi M.,
RA   Saliola M., Sanchez-Perez M., Schaefer B., Schaefer M., Scharfe M.,
RA   Schmidheini T., Schreer A., Skala J., Souciet J.-L., Steensma H.Y.,
RA   Talla E., Thierry A., Vandenbol M., van der Aart Q.J.M., Van Dyck L.,
RA   Vanoni M., Verhasselt P., Voet M., Volckaert G., Wambutt R., Watson M.D.,
RA   Weber N., Wedler E., Wedler H., Wipfli P., Wolf K., Wright L.F.,
RA   Zaccaria P., Zimmermann M., Zollner A., Kleine K.;
RT   "The nucleotide sequence of Saccharomyces cerevisiae chromosome VII.";
RL   Nature 387:81-84(1997).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=24374639; DOI=10.1534/g3.113.008995;
RA   Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA   Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA   Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT   "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL   G3 (Bethesda) 4:389-398(2014).
RN   [3]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=18407956; DOI=10.1074/mcp.m700468-mcp200;
RA   Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
RT   "A multidimensional chromatography technology for in-depth phosphoproteome
RT   analysis.";
RL   Mol. Cell. Proteomics 7:1389-1396(2008).
RN   [4]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=22814378; DOI=10.1073/pnas.1210303109;
RA   Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A.,
RA   Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E., Timmerman E.,
RA   Prieto J., Arnesen T., Sherman F., Gevaert K., Aldabe R.;
RT   "N-terminal acetylome analyses and functional insights of the N-terminal
RT   acetyltransferase NatB.";
RL   Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the oligopeptide OPT transporter family.
CC       {ECO:0000305}.
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DR   EMBL; Z72636; CAA96822.1; -; Genomic_DNA.
DR   EMBL; BK006941; DAA07994.1; -; Genomic_DNA.
DR   PIR; S64124; S64124.
DR   RefSeq; NP_011401.1; NM_001180979.1.
DR   AlphaFoldDB; P53134; -.
DR   SMR; P53134; -.
DR   BioGRID; 33137; 174.
DR   DIP; DIP-7780N; -.
DR   STRING; 4932.YGL114W; -.
DR   TCDB; 2.A.67.2.7; the oligopeptide transporter (opt) family.
DR   iPTMnet; P53134; -.
DR   MaxQB; P53134; -.
DR   PaxDb; 4932-YGL114W; -.
DR   PeptideAtlas; P53134; -.
DR   EnsemblFungi; YGL114W_mRNA; YGL114W; YGL114W.
DR   GeneID; 852764; -.
DR   KEGG; sce:YGL114W; -.
DR   AGR; SGD:S000003082; -.
DR   SGD; S000003082; YGL114W.
DR   VEuPathDB; FungiDB:YGL114W; -.
DR   eggNOG; ENOG502QQ2H; Eukaryota.
DR   HOGENOM; CLU_010539_2_0_1; -.
DR   InParanoid; P53134; -.
DR   OMA; EDRKGHW; -.
DR   OrthoDB; 362380at2759; -.
DR   BioCyc; YEAST:G3O-30612-MONOMER; -.
DR   BioGRID-ORCS; 852764; 1 hit in 10 CRISPR screens.
DR   ChiTaRS; YGL114W; yeast.
DR   PRO; PR:P53134; -.
DR   Proteomes; UP000002311; Chromosome VII.
DR   RNAct; P53134; Protein.
DR   GO; GO:0000329; C:fungal-type vacuole membrane; HDA:SGD.
DR   GO; GO:0016020; C:membrane; IBA:GO_Central.
DR   GO; GO:0005886; C:plasma membrane; ISS:SGD.
DR   GO; GO:0035673; F:oligopeptide transmembrane transporter activity; ISS:SGD.
DR   GO; GO:0006857; P:oligopeptide transport; ISS:SGD.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR004813; OPT.
DR   InterPro; IPR045035; YSL-like.
DR   NCBIfam; TIGR00728; OPT_sfam; 1.
DR   PANTHER; PTHR31645; OLIGOPEPTIDE TRANSPORTER YGL114W-RELATED; 1.
DR   PANTHER; PTHR31645:SF0; OLIGOPEPTIDE TRANSPORTER YGL114W-RELATED; 1.
DR   Pfam; PF03169; OPT; 1.
PE   1: Evidence at protein level;
KW   Membrane; Peptide transport; Protein transport; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..725
FT                   /note="Putative oligopeptide transporter YGL114W"
FT                   /id="PRO_0000213789"
FT   TRANSMEM        28..48
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        134..154
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        254..274
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        353..373
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        449..469
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        472..492
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        564..584
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        644..664
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        697..717
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   725 AA;  80009 MW;  23FCAF5988758F1B CRC64;
     MPQSTPSQEV QRVPWDNKPA LKQITLRATI AGIAIGSLVL TSNFQFGLQT GWVSMMSLPS
     ALLACAFFKN IWPLIFPNDR PFSDVENVYV QSMAVAVGTG PLAFGFVGVI PAIEKFLTND
     ESGGLREQGQ SFTFRELLIW STALAFFGIF FAVPLRKQVI VREKLPFPSG SATATLISVL
     NGTEILQEVS KSELLEMRQR RLNECPEVLQ PNRDPEEADY LMNSSHSELG DYTATSQDGS
     SILSTGSENY RANIIILLKT FVVSSLYTMV SYFVPVIRSI PVFGKYLSNN YLWNFQPSPA
     YIGQGIIMGL PTVSYMLIGC FLGWGVLAPL ARYKRWVPPD ADVHDWEEGV QGWILWSSLS
     IMVADSVVAF IVVTVKSIVK FILIDDKAAL LNNIIDDTFQ SMLLEEERAI NSSRRNTYVD
     GRQDTVRLVS RDNEIEVDSK HLVRYTTVIS GCLVSSIICI VSIIYLFGIQ VIPLYAIITA
     LILALFLSIL GIRALGETDL NPVSGIGKIS QLIFAFIIPR DRPGSVLMNV VSGGIAEASA
     QQAGDLMQDL KTGHLLGASP RAQFCAQLIG ACWSIILSSF MYLCYNKVYS IPSEQFRIPT
     AVVWIDCARL VTGKGLPDKA LECSMILGVI FAVLSLIRNT YRDYGYGWIL YIPSGVAVGV
     GIFNSPSFTI ARFIGGWASH FWLKNHRGDL NAKTKMIVFS SGLVLGEGIF SVINMLFICL
     NVPHY
//