Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Heterotrimeric G protein gamma subunit GPG1

Gene

GPG1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Gamma subunit of a guanine nucleotide-binding protein (G protein). G proteins are involved as modulators or transducers in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Involved in the determination of the cAMP level according to nutritional conditions, most probably as a regulator of cAMP phosphodiesterase. Required for the control of pseudohyphal and haploid invasive growth.1 Publication

GO - Molecular functioni

  • signal transducer activity Source: SGD

GO - Biological processi

  • invasive growth in response to glucose limitation Source: SGD
  • signal transduction Source: SGD

Keywordsi

Molecular functionTransducer

Enzyme and pathway databases

BioCyciYEAST:G3O-30618-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Heterotrimeric G protein gamma subunit GPG1
Gene namesi
Name:GPG1
Ordered Locus Names:YGL121C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome VII

Organism-specific databases

EuPathDBiFungiDB:YGL121C
SGDiS000003089 GPG1

Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002027451 – 126Heterotrimeric G protein gamma subunit GPG1Add BLAST126

Proteomic databases

MaxQBiP53130
PaxDbiP53130
PRIDEiP53130

Expressioni

Inductioni

By heat.1 Publication

Interactioni

Subunit structurei

G proteins are composed of 3 units, alpha, beta and gamma. GPG1 interacts with the beta subunits GBP1 and GPB2.1 Publication

Protein-protein interaction databases

BioGridi33130, 65 interactors
DIPiDIP-6469N
IntActiP53130, 5 interactors
MINTiP53130
STRINGi4932.YGL121C

Structurei

3D structure databases

ProteinModelPortaliP53130
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000000924
InParanoidiP53130
OMAiWDLENIV
OrthoDBiEOG092C5JCG

Sequencei

Sequence statusi: Complete.

P53130-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFYLSDIEEE ASAGAEPTYN FWEVLLFSNT QENLVTVVGE LHTLTDRVVH
60 70 80 90 100
YKIEPESREV TATTLPSLLA LLLEKRNQAR RLYRDVLSMK MSELDWDIDD
110 120
LFTQLQEELT RTDDTLSMYP RRRFYH
Length:126
Mass (Da):14,922
Last modified:October 1, 1996 - v1
Checksum:i8F1CADCFCF3F657E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z72643 Genomic DNA Translation: CAA96829.1
BK006941 Genomic DNA Translation: DAA07988.1
PIRiS64131
RefSeqiNP_011394.1, NM_001180986.1

Genome annotation databases

EnsemblFungiiYGL121C; YGL121C; YGL121C
GeneIDi852756
KEGGisce:YGL121C

Similar proteinsi

Entry informationi

Entry nameiGPG1_YEAST
AccessioniPrimary (citable) accession number: P53130
Secondary accession number(s): D6VU27
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: May 23, 2018
This is version 109 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health