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P53118 (ROG1_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 102. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative lipase ROG1

EC=3.1.-.-
Alternative name(s):
Revertant of glycogen synthase kinase mutation protein 1
Gene names
Name:ROG1
Ordered Locus Names:YGL144C
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length685 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Sequence similarities

Belongs to the putative lipase ROG1 family.

Binary interactions

With

Entry

#Exp.

IntAct

Notes

LSB3P436032EBI-24005,EBI-22980

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 685685Putative lipase ROG1
PRO_0000202735

Sites

Active site2691Charge relay system By similarity

Experimental info

Sequence conflict5141F → S in AAU09729. Ref.4

Sequences

Sequence LengthMass (Da)Tools
P53118 [UniParc].

Last modified October 1, 1996. Version 1.
Checksum: BE800C5E15148E4A

FASTA68578,142
        10         20         30         40         50         60 
MSLTPTNEIL FHYKSSVKVG ELERYVITYH LYDGEEIPPD LNLNSLWLKV RNMNPLSYRA 

        70         80         90        100        110        120 
AYLMGPFMLY CDVKTAQYHH SQKIVASVDY PKFEPNVQTQ QDFVAELSVH NIRQKYVWIA 

       130        140        150        160        170        180 
DVMSQILFTT NTNVTYEVTI GTSKESVENP HDLPSHLGSY SPKLTVNRLT TLDLWNLPVQ 

       190        200        210        220        230        240 
ITTPQKKKHL VVLTHGLHSN VSTDLVYIME QIYKAQKNYP HEQIVVKGYR GNVCQTEKGV 

       250        260        270        280        290        300 
KYLGTRLAEY IIQDLYDESI RKISFVGHSL GGLIQAFAIA YIYEVYPWFF KKVNPINFIT 

       310        320        330        340        350        360 
LASPLLGIVT DNPAYIKVLL SFGVIGKTGQ DLGLENDVEV GKPLLYLLSG LPLIEILRRF 

       370        380        390        400        410        420 
KRRTVYANAI NDGIVPLYTA SLLFLDYNDI LEQLQKLKEN SKKSPLINDA STPVNQDFFN 

       430        440        450        460        470        480 
KTFISPLTKM LSILAPQKFP TENGSEIPKV SFFESASSIL LPPLPERAYI MDPDSRDPVI 

       490        500        510        520        530        540 
IHDKIYNEDD IPQSEFDIED GFFGKKNILL QAFFAGKKER AKYRNLEETI ARRWHEGMAW 

       550        560        570        580        590        600 
RKVVVALKPD AHNNIIVRRK FANAYGWPVI DHLIDVHFNG DDDDDNDEND DINSTQVVEP 

       610        620        630        640        650        660 
IQSVTEGKKK YRKAENIPQE YGWLNKVETN GVFDEGPTGM ISTVGEIVEA LAKRGFSAVI 

       670        680 
DRRNASEDPN DEVLRFEEMN SDLVQ 

« Hide

References

« Hide 'large scale' references
[1]"The sequence of a nearly unclonable 22.8 kb segment on the left arm chromosome VII from Saccharomyces cerevisiae reveals ARO2, RPL9A, TIP1, MRF1 genes and six new open reading frames."
Voet M., Defoor E., Verhasselt P., Riles L., Robben J., Volckaert G.
Yeast 13:177-182(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 96604 / S288c / FY1679.
[2]"The nucleotide sequence of Saccharomyces cerevisiae chromosome VII."
Tettelin H., Agostoni-Carbone M.L., Albermann K., Albers M., Arroyo J., Backes U., Barreiros T., Bertani I., Bjourson A.J., Brueckner M., Bruschi C.V., Carignani G., Castagnoli L., Cerdan E., Clemente M.L., Coblenz A., Coglievina M., Coissac E. expand/collapse author list , Defoor E., Del Bino S., Delius H., Delneri D., de Wergifosse P., Dujon B., Durand P., Entian K.-D., Eraso P., Escribano V., Fabiani L., Fartmann B., Feroli F., Feuermann M., Frontali L., Garcia-Gonzalez M., Garcia-Saez M.I., Goffeau A., Guerreiro P., Hani J., Hansen M., Hebling U., Hernandez K., Heumann K., Hilger F., Hofmann B., Indge K.J., James C.M., Klima R., Koetter P., Kramer B., Kramer W., Lauquin G., Leuther H., Louis E.J., Maillier E., Marconi A., Martegani E., Mazon M.J., Mazzoni C., McReynolds A.D.K., Melchioretto P., Mewes H.-W., Minenkova O., Mueller-Auer S., Nawrocki A., Netter P., Neu R., Nombela C., Oliver S.G., Panzeri L., Paoluzi S., Plevani P., Portetelle D., Portillo F., Potier S., Purnelle B., Rieger M., Riles L., Rinaldi T., Robben J., Rodrigues-Pousada C., Rodriguez-Belmonte E., Rodriguez-Torres A.M., Rose M., Ruzzi M., Saliola M., Sanchez-Perez M., Schaefer B., Schaefer M., Scharfe M., Schmidheini T., Schreer A., Skala J., Souciet J.-L., Steensma H.Y., Talla E., Thierry A., Vandenbol M., van der Aart Q.J.M., Van Dyck L., Vanoni M., Verhasselt P., Voet M., Volckaert G., Wambutt R., Watson M.D., Weber N., Wedler E., Wedler H., Wipfli P., Wolf K., Wright L.F., Zaccaria P., Zimmermann M., Zollner A., Kleine K.
Nature 387:81-84(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]"The reference genome sequence of Saccharomyces cerevisiae: Then and now."
Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R., Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S., Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.
G3 (Bethesda) 4:389-398(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[4]"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae."
Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. expand/collapse author list , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J.
Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X99960 Genomic DNA. Translation: CAA68218.1.
Z72666 Genomic DNA. Translation: CAA96856.1.
AY723812 Genomic DNA. Translation: AAU09729.1.
BK006941 Genomic DNA. Translation: DAA07966.1.
PIRS64158.
RefSeqNP_011371.1. NM_001181009.1.

3D structure databases

ProteinModelPortalP53118.
SMRP53118. Positions 189-308.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid33108. 24 interactions.
IntActP53118. 3 interactions.
MINTMINT-597995.
STRING4932.YGL144C.

Proteomic databases

MaxQBP53118.
PaxDbP53118.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYGL144C; YGL144C; YGL144C.
GeneID852733.
KEGGsce:YGL144C.

Organism-specific databases

CYGDYGL144c.
SGDS000003112. ROG1.

Phylogenomic databases

eggNOGNOG316299.
GeneTreeENSGT00390000013022.
HOGENOMHOG000094252.
OMAHGLHSNV.
OrthoDBEOG7VHT5J.

Enzyme and pathway databases

BioCycYEAST:G3O-30638-MONOMER.

Gene expression databases

GenevestigatorP53118.

Family and domain databases

Gene3D3.40.50.1820. 1 hit.
InterProIPR029058. AB_hydrolase.
IPR007751. DUF676_lipase-like.
IPR016445. Lipase_YDL109c.
[Graphical view]
PfamPF05057. DUF676. 1 hit.
[Graphical view]
PIRSFPIRSF005412. UCP005412_abhydr. 1 hit.
SUPFAMSSF53474. SSF53474. 1 hit.
PROSITEPS00120. LIPASE_SER. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio972132.

Entry information

Entry nameROG1_YEAST
AccessionPrimary (citable) accession number: P53118
Secondary accession number(s): D6VU05, Q66RA3
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: June 11, 2014
This is version 102 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome VII

Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families