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Protein

Suppressor of disruption of TFIIS

Gene

SDT1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Could be an enzyme that inactivates 6-azauracil by modifying it.

GO - Molecular functioni

  • nucleotidase activity Source: SGD

GO - Biological processi

  • pyrimidine nucleobase metabolic process Source: SGD

Enzyme and pathway databases

BioCyciYEAST:G3O-30698-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Suppressor of disruption of TFIIS
Gene namesi
Name:SDT1
Synonyms:SSM1
Ordered Locus Names:YGL224C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome VII

Organism-specific databases

EuPathDBiFungiDB:YGL224C
SGDiS000003192 SDT1

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000722131 – 280Suppressor of disruption of TFIISAdd BLAST280

Proteomic databases

MaxQBiP53078
PaxDbiP53078
PRIDEiP53078

Interactioni

Protein-protein interaction databases

BioGridi33035, 39 interactors
STRINGi4932.YGL224C

Structurei

Secondary structure

1280
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi6 – 29Combined sources24
Beta strandi57 – 60Combined sources4
Turni63 – 65Combined sources3
Helixi71 – 87Combined sources17
Helixi93 – 106Combined sources14
Helixi108 – 116Combined sources9
Helixi122 – 129Combined sources8
Turni130 – 132Combined sources3
Helixi135 – 137Combined sources3
Helixi143 – 154Combined sources12
Beta strandi155 – 157Combined sources3
Beta strandi159 – 164Combined sources6
Helixi169 – 178Combined sources10
Beta strandi186 – 189Combined sources4
Helixi205 – 215Combined sources11
Helixi220 – 222Combined sources3
Beta strandi223 – 228Combined sources6
Helixi230 – 239Combined sources10
Beta strandi242 – 247Combined sources6
Beta strandi249 – 251Combined sources3
Helixi254 – 256Combined sources3
Beta strandi264 – 268Combined sources5
Helixi269 – 274Combined sources6
Helixi277 – 279Combined sources3

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3NUQX-ray1.70A1-280[»]
3ONNX-ray1.87A26-280[»]
3OPXX-ray1.70A26-280[»]
ProteinModelPortaliP53078
SMRiP53078
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP53078

Family & Domainsi

Sequence similaritiesi

Belongs to the SSM1 family.Curated

Phylogenomic databases

GeneTreeiENSGT00390000005824
InParanoidiP53078
KOiK18551
OMAiNIHNIKE
OrthoDBiEOG092C47TF

Family and domain databases

CDDicd02604 HAD_5NT, 1 hit
Gene3Di3.40.50.1000, 2 hits
InterProiView protein in InterPro
IPR036412 HAD-like_sf
IPR006439 HAD-SF_hydro_IA
IPR023214 HAD_sf
IPR010237 Pyr-5-nucltdase
SFLDiSFLDG01132 C1.5.3:_5'-Nucleotidase_Like, 1 hit
SUPFAMiSSF56784 SSF56784, 1 hit
TIGRFAMsiTIGR01509 HAD-SF-IA-v3, 1 hit
TIGR01993 Pyr-5-nucltdase, 1 hit

Sequencei

Sequence statusi: Complete.

P53078-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTVEYTASDL ATYQNEVNEQ IAKNKAHLES LTHPGSKVTF PIDQDISATP
60 70 80 90 100
QNPNLKVFFF DIDNCLYKSS TRIHDLMQQS ILRFFQTHLK LSPEDAHVLN
110 120 130 140 150
NSYYKEYGLA IRGLVMFHKV NALEYNRLVD DSLPLQDILK PDIPLRNMLL
160 170 180 190 200
RLRQSGKIDK LWLFTNAYKN HAIRCLRLLG IADLFDGLTY CDYSRTDTLV
210 220 230 240 250
CKPHVKAFEK AMKESGLARY ENAYFIDDSG KNIETGIKLG MKTCIHLVEN
260 270 280
EVNEILGQTP EGAIVISDIL ELPHVVSDLF
Length:280
Mass (Da):31,969
Last modified:October 1, 1996 - v1
Checksum:i680F66359CD57B8B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D26043 Genomic DNA Translation: BAB13723.1
Z72746 Genomic DNA Translation: CAA96940.1
AY692802 Genomic DNA Translation: AAT92821.1
BK006941 Genomic DNA Translation: DAA07895.1
PIRiS64246
RefSeqiNP_011291.1, NM_001181089.1

Genome annotation databases

EnsemblFungiiYGL224C; YGL224C; YGL224C
GeneIDi852648
KEGGisce:YGL224C

Similar proteinsi

Entry informationi

Entry nameiSDT1_YEAST
AccessioniPrimary (citable) accession number: P53078
Secondary accession number(s): D6VVB1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: May 23, 2018
This is version 129 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  4. Yeast chromosome VII
    Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names

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