Reviewed, UniProtKB/Swiss-Prot P53078 (SSM1_YEAST)

Names and origin

Protein names

Recommended name:
    Protein SSM1

Gene names

Name:	SSM1
Synonyms:	SDT1
Ordered Locus Names:	YGL224C

Organism

Saccharomyces cerevisiae (Baker's yeast) [Complete proteome]

Taxonomic identifier

4932 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	280 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Could be an enzyme that inactivates 6-azauracil by modifying it.
Sequence similarities	Belongs to the SSM1 family.

Ontologies

Keywords
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pyrimidine base metabolic process Inferred from mutant phenotype. Source: SGD
Molecular function	nucleotidase activity Inferred from direct assay. Source: SGD
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 280	280	Protein SSM1		PRO_0000072213

Sequences

	Sequence		Length	Mass (Da)
	P53078-1 [UniParc]. Last modified October 1, 1996. Version 1. Checksum: 680F66359CD57B8B	FASTA	280	31,969
	10 20 30 40 50 60 MTVEYTASDL ATYQNEVNEQ IAKNKAHLES LTHPGSKVTF PIDQDISATP QNPNLKVFFF 70 80 90 100 110 120 DIDNCLYKSS TRIHDLMQQS ILRFFQTHLK LSPEDAHVLN NSYYKEYGLA IRGLVMFHKV 130 140 150 160 170 180 NALEYNRLVD DSLPLQDILK PDIPLRNMLL RLRQSGKIDK LWLFTNAYKN HAIRCLRLLG 190 200 210 220 230 240 IADLFDGLTY CDYSRTDTLV CKPHVKAFEK AMKESGLARY ENAYFIDDSG KNIETGIKLG 250 260 270 280 MKTCIHLVEN EVNEILGQTP EGAIVISDIL ELPHVVSDLF

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Transcription elongation factor S-II confers yeast resistance to 6-azauracil by enhancing expression of the SSM1 gene." Shimoaraiso M., Nakanishi T., Kubo T., Natori S. J. Biol. Chem. 275:29623-29627(2000) [PubMed: 10858443] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Sequence analysis of 203 kilobases from Saccharomyces cerevisiae chromosome VII." Rieger M., Brueckner M., Schaefer M., Mueller-Auer S. Yeast 13:1077-1090(1997) [PubMed: 9290212] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[3]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome VII." Tettelin H., Agostoni-Carbone M.L., Albermann K., Albers M., Arroyo J., Backes U., Barreiros T., Bertani I., Bjourson A.J., Brueckner M., Bruschi C.V., Carignani G., Castagnoli L., Cerdan E., Clemente M.L., Coblenz A., Coglievina M., Coissac E. , Defoor E., Del Bino S., Delius H., Delneri D., de Wergifosse P., Dujon B., Durand P., Entian K.-D., Eraso P., Escribano V., Fabiani L., Fartmann B., Feroli F., Feuermann M., Frontali L., Garcia-Gonzalez M., Garcia-Saez M.I., Goffeau A., Guerreiro P., Hani J., Hansen M., Hebling U., Hernandez K., Heumann K., Hilger F., Hofmann B., Indge K.J., James C.M., Klima R., Koetter P., Kramer B., Kramer W., Lauquin G., Leuther H., Louis E.J., Maillier E., Marconi A., Martegani E., Mazon M.J., Mazzoni C., McReynolds A.D.K., Melchioretto P., Mewes H.-W., Minenkova O., Mueller-Auer S., Nawrocki A., Netter P., Neu R., Nombela C., Oliver S.G., Panzeri L., Paoluzi S., Plevani P., Portetelle D., Portillo F., Potier S., Purnelle B., Rieger M., Riles L., Rinaldi T., Robben J., Rodrigues-Pousada C., Rodriguez-Belmonte E., Rodriguez-Torres A.M., Rose M., Ruzzi M., Saliola M., Sanchez-Perez M., Schaefer B., Schaefer M., Scharfe M., Schmidheini T., Schreer A., Skala J., Souciet J.-L., Steensma H.Y., Talla E., Thierry A., Vandenbol M., van der Aart Q.J.M., Van Dyck L., Vanoni M., Verhasselt P., Voet M., Volckaert G., Wambutt R., Watson M.D., Weber N., Wedler E., Wedler H., Wipfli P., Wolf K., Wright L.F., Zaccaria P., Zimmermann M., Zollner A., Kleine K. Nature 387:81-84(1997) [PubMed: 9169869] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 96604 / S288c / FY1679.
[4]	"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae." Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J. Genome Res. 17:536-543(2007) [PubMed: 17322287] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	D26043 Genomic DNA. Translation: BAB13723.1. Z72746 Genomic DNA. Translation: CAA96940.1. AY692802 Genomic DNA. Translation: AAT92821.1.
PIR	S64246.
RefSeq	NP_011291.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	P53078.
Genome annotation databases
Ensembl	YGL224C; YGL224C; YGL224C; Saccharomyces cerevisiae. [Genome view]
GeneID	852648.
GenomeReviews	Gene locus YGL224C in contig Y13135_GR.
KEGG	sce:YGL224C.
NMPDR	fig|4932.3.peg.2394.
Organism-specific databases
CYGD	YGL224c.
SGD	S000003192. SDT1.
Phylogenomic databases
HOGENOM	P53078.
OMA	FDYDEYH.
Gene expression databases
ArrayExpress	P53078.
Genevestigator	P53078.
GermOnline	YGL224C. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR005834. Dehalogen-like_hydro. IPR006402. HAD-SF_hydro_IA_v3. IPR010237. Pyr-5-nucltdase. [Graphical view]
Pfam	PF00702. Hydrolase. 1 hit. [Graphical view]
TIGRFAMs	TIGR01509. HAD-SF-IA-v3. 1 hit. TIGR01993. Pyr-5-nucltdase. 1 hit.
ProtoNet	Search...
Other Resources
NextBio	971915.

Entry information

Entry name

SSM1_YEAST

Accession

Primary (citable) accession number: P53078

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1996
Last sequence update:	October 1, 1996
Last modified:	November 3, 2009
This is version 61 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)