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P53077 (MTC3_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Maintenance of telomere capping protein 3, mitochondrial
Gene names
Name:MTC3
Ordered Locus Names:YGL226W
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length123 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

May be involved in telomere capping. Ref.5

Subcellular location

Mitochondrion Ref.3.

Miscellaneous

Present with 1170 molecules/cell in log phase SD medium. Ref.6

Ontologies

Keywords
   Cellular componentMitochondrion
   DomainTransit peptide
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular componentmitochondrion

Inferred from direct assay Ref.3. Source: SGD

   Molecular functioncytochrome-c oxidase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide1 – 3737Mitochondrion
Chain38 – 12386Maintenance of telomere capping protein 3, mitochondrial
PRO_0000202714

Sequences

Sequence LengthMass (Da)Tools
P53077 [UniParc].

Last modified October 1, 1996. Version 1.
Checksum: A29F76EB9EB08EE4

FASTA12314,488
        10         20         30         40         50         60 
MMGRNGIRLA LKRSFSTYQP PVVEITNITK LWPTLRPEVR DEIKEYLRWR MQEDWRHIPL 

        70         80         90        100        110        120 
EETKAAYFLS YGPCGGRSKG NEWNVGYTGM RIVFNLVLFG GAATAFYNWK QDKKLEEQLR 


DLV

« Hide

References

« Hide 'large scale' references
[1]"The nucleotide sequence of Saccharomyces cerevisiae chromosome VII."
Tettelin H., Agostoni-Carbone M.L., Albermann K., Albers M., Arroyo J., Backes U., Barreiros T., Bertani I., Bjourson A.J., Brueckner M., Bruschi C.V., Carignani G., Castagnoli L., Cerdan E., Clemente M.L., Coblenz A., Coglievina M., Coissac E. expand/collapse author list , Defoor E., Del Bino S., Delius H., Delneri D., de Wergifosse P., Dujon B., Durand P., Entian K.-D., Eraso P., Escribano V., Fabiani L., Fartmann B., Feroli F., Feuermann M., Frontali L., Garcia-Gonzalez M., Garcia-Saez M.I., Goffeau A., Guerreiro P., Hani J., Hansen M., Hebling U., Hernandez K., Heumann K., Hilger F., Hofmann B., Indge K.J., James C.M., Klima R., Koetter P., Kramer B., Kramer W., Lauquin G., Leuther H., Louis E.J., Maillier E., Marconi A., Martegani E., Mazon M.J., Mazzoni C., McReynolds A.D.K., Melchioretto P., Mewes H.-W., Minenkova O., Mueller-Auer S., Nawrocki A., Netter P., Neu R., Nombela C., Oliver S.G., Panzeri L., Paoluzi S., Plevani P., Portetelle D., Portillo F., Potier S., Purnelle B., Rieger M., Riles L., Rinaldi T., Robben J., Rodrigues-Pousada C., Rodriguez-Belmonte E., Rodriguez-Torres A.M., Rose M., Ruzzi M., Saliola M., Sanchez-Perez M., Schaefer B., Schaefer M., Scharfe M., Schmidheini T., Schreer A., Skala J., Souciet J.-L., Steensma H.Y., Talla E., Thierry A., Vandenbol M., van der Aart Q.J.M., Van Dyck L., Vanoni M., Verhasselt P., Voet M., Volckaert G., Wambutt R., Watson M.D., Weber N., Wedler E., Wedler H., Wipfli P., Wolf K., Wright L.F., Zaccaria P., Zimmermann M., Zollner A., Kleine K.
Nature 387:81-84(1997) [PubMed: 9169869] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 96604 / S288c / FY1679.
[2]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[3]"Global analysis of protein localization in budding yeast."
Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K.
Nature 425:686-691(2003) [PubMed: 14562095] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[4]"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae."
Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. expand/collapse author list , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J.
Genome Res. 17:536-543(2007) [PubMed: 17322287] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[5]"A genomewide suppressor and enhancer analysis of cdc13-1 reveals varied cellular processes influencing telomere capping in Saccharomyces cerevisiae."
Addinall S.G., Downey M., Yu M., Zubko M.K., Dewar J., Leake A., Hallinan J., Shaw O., James K., Wilkinson D.J., Wipat A., Durocher D., Lydall D.
Genetics 180:2251-2266(2008) [PubMed: 18845848] [Abstract]
Cited for: FUNCTION.
[6]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed: 14562106] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		Z72748 Genomic DNA. Translation: CAA96942.1.
AY558266 Genomic DNA. Translation: AAS56592.1.
BK006941 Genomic DNA. Translation: DAA07893.1.
PIRS64248.
RefSeqNP_011289.1. NM_001181092.1.

3D structure databases

ProteinModelPortalP53077.
ModBaseSearch...

Protein-protein interaction databases

DIPDIP-4725N.
MINTMINT-532992.
STRINGP53077.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYGL226W; YGL226W; YGL226W.
GeneID852626.
KEGGsce:YGL226W.
NMPDRfig|4932.3.peg.2392.

Organism-specific databases

CYGDYGL226w.
SGDS000003195. MTC3.

Phylogenomic databases

eggNOGfuNOG11915.
OMAHASTEAY.
OrthoDBEOG498Z9M.

Gene expression databases

ArrayExpressP53077.
GenevestigatorP53077.
GermOnlineYGL226W. Saccharomyces cerevisiae.

Family and domain databases

InterProIPR004203. Cyt_c_oxidase_su4.
[Graphical view]
Gene3DG3DSA:1.10.442.10. COX4. 1 hit.
PfamPF02936. COX4. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio971850.

Entry information

Entry nameMTC3_YEAST
AccessionPrimary (citable) accession number: P53077
Secondary accession number(s): D6VVA9
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: December 14, 2011
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

Yeast chromosome VII

Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names

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