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Protein

tRNA acetyltransferase TAN1

Gene

TAN1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Probable tRNA acetyltransferase required for the formation of the modified nucleoside N4-acetylcytidine in serine and leucine tRNAs. Binds RNA.1 Publication

Miscellaneous

Present with 2630 molecules/cell in log phase SD medium.1 Publication

GO - Molecular functioni

  • RNA binding Source: SGD
  • transferase activity, transferring acyl groups Source: UniProtKB-KW

GO - Biological processi

  • tRNA modification Source: SGD

Keywordsi

Molecular functionAcyltransferase, RNA-binding, Transferase
Biological processtRNA processing

Enzyme and pathway databases

BioCyciYEAST:G3O-30706-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA acetyltransferase TAN1 (EC:2.3.-.-)
Gene namesi
Name:TAN1
Ordered Locus Names:YGL232W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome VII

Organism-specific databases

EuPathDBiFungiDB:YGL232W
SGDiS000003201 TAN1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000724261 – 289tRNA acetyltransferase TAN1Add BLAST289

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei72PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiP53072
PaxDbiP53072
PRIDEiP53072

PTM databases

iPTMnetiP53072

Interactioni

Protein-protein interaction databases

BioGridi33007, 85 interactors
IntActiP53072, 2 interactors
MINTiP53072
STRINGi4932.YGL232W

Structurei

3D structure databases

ProteinModelPortaliP53072
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini146 – 259THUMPPROSITE-ProRule annotationAdd BLAST114

Phylogenomic databases

GeneTreeiENSGT00390000002365
HOGENOMiHOG000065974
InParanoidiP53072
KOiK06963
OMAiKFNVMEI
OrthoDBiEOG092C4BHK

Family and domain databases

InterProiView protein in InterPro
IPR004114 THUMP_dom
PfamiView protein in Pfam
PF02926 THUMP, 1 hit
SMARTiView protein in SMART
SM00981 THUMP, 1 hit
PROSITEiView protein in PROSITE
PS51165 THUMP, 1 hit

Sequencei

Sequence statusi: Complete.

P53072-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGEKRNRNGK DANSQNRKKF KVSSGFLDPG TSGIYATCSR RHERQAAQEL
60 70 80 90 100
QLLFEEKFQE LYGDIKEGED ESENDEKKDL SIEDQIKKEL QELKGEETGK
110 120 130 140 150
DLSSGETKKK DPLAFIDLNC ECVTFCKTRK PIVPEEFVLS IMKDLADPKN
160 170 180 190 200
MVKRTRYVQK LTPITYSCNA KMEQLIKLAN LVIGPHFHDP SNVKKNYKFA
210 220 230 240 250
VEVTRRNFNT IERMDIINQV VKLVNKEGSE FNHTVDLKNY DKLILVECFK
260 270 280
SNIGMCVVDG DYKTKYRKYN VQQLYESKFR KDEDKSVKQ
Length:289
Mass (Da):33,550
Last modified:October 1, 1996 - v1
Checksum:i0E1C8C55E70CEB28
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z72754 Genomic DNA Translation: CAA96950.1
BK006941 Genomic DNA Translation: DAA07886.1
PIRiS64254
RefSeqiNP_011282.1, NM_001181098.1

Genome annotation databases

EnsemblFungiiYGL232W; YGL232W; YGL232W
GeneIDi852619
KEGGisce:YGL232W

Similar proteinsi

Entry informationi

Entry nameiTAN1_YEAST
AccessioniPrimary (citable) accession number: P53072
Secondary accession number(s): D6VVA2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: May 23, 2018
This is version 126 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome VII
    Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names

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