ID   YGZ2_YEAST              Reviewed;         181 AA.
AC   P53066; D6VV93;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   08-NOV-2023, entry version 161.
DE   RecName: Full=Ankyrin repeat-containing protein YGL242C;
GN   OrderedLocusNames=YGL242C; ORFNames=HRE181;
OS   Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=559292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=8750240; DOI=10.1002/yea.320111507;
RA   Vandenbol M., Durand P., Portetelle D., Hilger F.;
RT   "The sequence of an 11.1 kb DNA fragment between ADH4 and ADE5 on the left
RT   arm of chromosome VII, reveals the presence of eight open reading frames.";
RL   Yeast 11:1519-1523(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=9169869;
RA   Tettelin H., Agostoni-Carbone M.L., Albermann K., Albers M., Arroyo J.,
RA   Backes U., Barreiros T., Bertani I., Bjourson A.J., Brueckner M.,
RA   Bruschi C.V., Carignani G., Castagnoli L., Cerdan E., Clemente M.L.,
RA   Coblenz A., Coglievina M., Coissac E., Defoor E., Del Bino S., Delius H.,
RA   Delneri D., de Wergifosse P., Dujon B., Durand P., Entian K.-D., Eraso P.,
RA   Escribano V., Fabiani L., Fartmann B., Feroli F., Feuermann M.,
RA   Frontali L., Garcia-Gonzalez M., Garcia-Saez M.I., Goffeau A.,
RA   Guerreiro P., Hani J., Hansen M., Hebling U., Hernandez K., Heumann K.,
RA   Hilger F., Hofmann B., Indge K.J., James C.M., Klima R., Koetter P.,
RA   Kramer B., Kramer W., Lauquin G., Leuther H., Louis E.J., Maillier E.,
RA   Marconi A., Martegani E., Mazon M.J., Mazzoni C., McReynolds A.D.K.,
RA   Melchioretto P., Mewes H.-W., Minenkova O., Mueller-Auer S., Nawrocki A.,
RA   Netter P., Neu R., Nombela C., Oliver S.G., Panzeri L., Paoluzi S.,
RA   Plevani P., Portetelle D., Portillo F., Potier S., Purnelle B., Rieger M.,
RA   Riles L., Rinaldi T., Robben J., Rodrigues-Pousada C.,
RA   Rodriguez-Belmonte E., Rodriguez-Torres A.M., Rose M., Ruzzi M.,
RA   Saliola M., Sanchez-Perez M., Schaefer B., Schaefer M., Scharfe M.,
RA   Schmidheini T., Schreer A., Skala J., Souciet J.-L., Steensma H.Y.,
RA   Talla E., Thierry A., Vandenbol M., van der Aart Q.J.M., Van Dyck L.,
RA   Vanoni M., Verhasselt P., Voet M., Volckaert G., Wambutt R., Watson M.D.,
RA   Weber N., Wedler E., Wedler H., Wipfli P., Wolf K., Wright L.F.,
RA   Zaccaria P., Zimmermann M., Zollner A., Kleine K.;
RT   "The nucleotide sequence of Saccharomyces cerevisiae chromosome VII.";
RL   Nature 387:81-84(1997).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=24374639; DOI=10.1534/g3.113.008995;
RA   Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA   Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA   Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT   "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL   G3 (Bethesda) 4:389-398(2014).
RN   [4]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-172, AND IDENTIFICATION BY
RP   MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=18407956; DOI=10.1074/mcp.m700468-mcp200;
RA   Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
RT   "A multidimensional chromatography technology for in-depth phosphoproteome
RT   analysis.";
RL   Mol. Cell. Proteomics 7:1389-1396(2008).
RN   [5]
RP   ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1, AND IDENTIFICATION BY MASS
RP   SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=22814378; DOI=10.1073/pnas.1210303109;
RA   Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A.,
RA   Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E., Timmerman E.,
RA   Prieto J., Arnesen T., Sherman F., Gevaert K., Aldabe R.;
RT   "N-terminal acetylome analyses and functional insights of the N-terminal
RT   acetyltransferase NatB.";
RL   Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012).
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DR   EMBL; Z49149; CAA89013.1; -; Genomic_DNA.
DR   EMBL; Z72764; CAA96961.1; -; Genomic_DNA.
DR   EMBL; BK006941; DAA07877.1; -; Genomic_DNA.
DR   PIR; S53938; S53938.
DR   RefSeq; NP_011272.1; NM_001181108.1.
DR   AlphaFoldDB; P53066; -.
DR   SMR; P53066; -.
DR   BioGRID; 32998; 166.
DR   DIP; DIP-1859N; -.
DR   IntAct; P53066; 2.
DR   MINT; P53066; -.
DR   STRING; 4932.YGL242C; -.
DR   iPTMnet; P53066; -.
DR   MaxQB; P53066; -.
DR   PaxDb; 4932-YGL242C; -.
DR   PeptideAtlas; P53066; -.
DR   EnsemblFungi; YGL242C_mRNA; YGL242C; YGL242C.
DR   GeneID; 852609; -.
DR   KEGG; sce:YGL242C; -.
DR   AGR; SGD:S000003211; -.
DR   SGD; S000003211; YGL242C.
DR   VEuPathDB; FungiDB:YGL242C; -.
DR   eggNOG; ENOG502S4CU; Eukaryota.
DR   HOGENOM; CLU_097653_0_0_1; -.
DR   InParanoid; P53066; -.
DR   OMA; HICAMYG; -.
DR   OrthoDB; 1363908at2759; -.
DR   BioCyc; YEAST:G3O-30714-MONOMER; -.
DR   BioGRID-ORCS; 852609; 0 hits in 10 CRISPR screens.
DR   PRO; PR:P53066; -.
DR   Proteomes; UP000002311; Chromosome VII.
DR   RNAct; P53066; Protein.
DR   Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   Pfam; PF12796; Ank_2; 1.
DR   SMART; SM00248; ANK; 2.
DR   SUPFAM; SSF48403; Ankyrin repeat; 1.
DR   PROSITE; PS50297; ANK_REP_REGION; 1.
DR   PROSITE; PS50088; ANK_REPEAT; 1.
PE   1: Evidence at protein level;
KW   Acetylation; ANK repeat; Phosphoprotein; Reference proteome; Repeat.
FT   CHAIN           1..181
FT                   /note="Ankyrin repeat-containing protein YGL242C"
FT                   /id="PRO_0000067245"
FT   REPEAT          49..78
FT                   /note="ANK 1"
FT   REPEAT          85..120
FT                   /note="ANK 2"
FT   REGION          151..181
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        162..181
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         1
FT                   /note="N-acetylmethionine"
FT                   /evidence="ECO:0007744|PubMed:22814378"
FT   MOD_RES         172
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:18407956"
SQ   SEQUENCE   181 AA;  20074 MW;  D836B9668DF644D4 CRC64;
     MNTEGASLSE QLLDAARRNN LDLLETVFDS LDNDPEKIAK LINESKEPLG NTALHLCCKY
     GSWEVLDKIL DQDGEIEIDP QNDVDGDTPL HVTVRYSQEE PEHGTFIARN LIEVGADPRV
     RNYNNQKPVD LVHGDELDEL IDLLQGAELA IDSTNGSGDN NEDGEMIDDG PSDDDEEDDK
     K
//