Reviewed, UniProtKB/Swiss-Prot P53066 (YGZ2_YEAST)

Names and origin

Protein names

Recommended name:
    Ankyrin repeat-containing protein YGL242C

Gene names

Ordered Locus Names:	YGL242C
ORF Names:	HRE181

Organism

Saccharomyces cerevisiae (Baker's yeast) [Complete proteome]

Taxonomic identifier

4932 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	181 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Sequence similarities

Contains 2 ANK repeats.

Ontologies

Keywords
Domain	ANK repeat Repeat
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	protein binding Inferred from physical interaction. Source: IntAct
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
MYO5	Q04439	1	EBI-24202,EBI-11687

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 181	181	Ankyrin repeat-containing protein YGL242C		PRO_0000067245
Regions
	Repeat	49 – 78	30	ANK 1
	Repeat	85 – 120	36	ANK 2
Amino acid modifications
	Modified residue	172	1	Phosphoserine Ref.3

Sequences

	Sequence		Length	Mass (Da)
	P53066-1 [UniParc]. Last modified October 1, 1996. Version 1. Checksum: D836B9668DF644D4	FASTA	181	20,074
	10 20 30 40 50 60 MNTEGASLSE QLLDAARRNN LDLLETVFDS LDNDPEKIAK LINESKEPLG NTALHLCCKY 70 80 90 100 110 120 GSWEVLDKIL DQDGEIEIDP QNDVDGDTPL HVTVRYSQEE PEHGTFIARN LIEVGADPRV 130 140 150 160 170 180 RNYNNQKPVD LVHGDELDEL IDLLQGAELA IDSTNGSGDN NEDGEMIDDG PSDDDEEDDK K

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The sequence of an 11.1 kb DNA fragment between ADH4 and ADE5 on the left arm of chromosome VII, reveals the presence of eight open reading frames." Vandenbol M., Durand P., Portetelle D., Hilger F. Yeast 11:1519-1523(1995) [PubMed: 8750240] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[2]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome VII." Tettelin H., Agostoni-Carbone M.L., Albermann K., Albers M., Arroyo J., Backes U., Barreiros T., Bertani I., Bjourson A.J., Brueckner M., Bruschi C.V., Carignani G., Castagnoli L., Cerdan E., Clemente M.L., Coblenz A., Coglievina M., Coissac E. , Defoor E., Del Bino S., Delius H., Delneri D., de Wergifosse P., Dujon B., Durand P., Entian K.-D., Eraso P., Escribano V., Fabiani L., Fartmann B., Feroli F., Feuermann M., Frontali L., Garcia-Gonzalez M., Garcia-Saez M.I., Goffeau A., Guerreiro P., Hani J., Hansen M., Hebling U., Hernandez K., Heumann K., Hilger F., Hofmann B., Indge K.J., James C.M., Klima R., Koetter P., Kramer B., Kramer W., Lauquin G., Leuther H., Louis E.J., Maillier E., Marconi A., Martegani E., Mazon M.J., Mazzoni C., McReynolds A.D.K., Melchioretto P., Mewes H.-W., Minenkova O., Mueller-Auer S., Nawrocki A., Netter P., Neu R., Nombela C., Oliver S.G., Panzeri L., Paoluzi S., Plevani P., Portetelle D., Portillo F., Potier S., Purnelle B., Rieger M., Riles L., Rinaldi T., Robben J., Rodrigues-Pousada C., Rodriguez-Belmonte E., Rodriguez-Torres A.M., Rose M., Ruzzi M., Saliola M., Sanchez-Perez M., Schaefer B., Schaefer M., Scharfe M., Schmidheini T., Schreer A., Skala J., Souciet J.-L., Steensma H.Y., Talla E., Thierry A., Vandenbol M., van der Aart Q.J.M., Van Dyck L., Vanoni M., Verhasselt P., Voet M., Volckaert G., Wambutt R., Watson M.D., Weber N., Wedler E., Wedler H., Wipfli P., Wolf K., Wright L.F., Zaccaria P., Zimmermann M., Zollner A., Kleine K. Nature 387:81-84(1997) [PubMed: 9169869] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[3]	"A multidimensional chromatography technology for in-depth phosphoproteome analysis." Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H. Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed: 18407956] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-172, MASS SPECTROMETRY.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	Z49149 Genomic DNA. Translation: CAA89013.1. Z72764 Genomic DNA. Translation: CAA96961.1.
PIR	S53938.
RefSeq	NP_011272.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
DIP	DIP:1859N.
IntAct	P53066. 3 interactions.
STRING	P53066.
Proteomic databases
PeptideAtlas	P53066.
PRIDE	P53066.
Genome annotation databases
Ensembl	YGL242C; YGL242C; YGL242C; Saccharomyces cerevisiae. [Genome view]
GeneID	852609.
GenomeReviews	Gene locus YGL242C in contig Y13135_GR.
KEGG	sce:YGL242C.
NMPDR	fig|4932.3.peg.2375.
Organism-specific databases
CYGD	YGL242c.
SGD	S000003211. YGL242C.
Phylogenomic databases
HOGENOM	P53066.
OMA	WEFIDIV.
Gene expression databases
ArrayExpress	P53066.
Genevestigator	P53066.
GermOnline	YGL242C. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR002110. ANK. [Graphical view]
Gene3D	G3DSA:1.25.40.20. ANK. 1 hit.
Pfam	PF00023. Ank. 2 hits. [Graphical view]
SMART	SM00248. ANK. 2 hits. [Graphical view]
PROSITE	PS50297. ANK_REP_REGION. 1 hit. PS50088. ANK_REPEAT. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	971802.

Entry information

Entry name

YGZ2_YEAST

Accession

Primary (citable) accession number: P53066

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1996
Last sequence update:	October 1, 1996
Last modified:	November 3, 2009
This is version 68 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)