P53060 (RMR1_YEAST) Reviewed, UniProtKB/Swiss-Prot
Last modified
December 14, 2011.
Version 74.
History...
Names·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Reduced meiotic recombination protein 1 | ||||||
| Gene names |
| ||||||
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | ||||||
| Taxonomic identifier | 559292 [NCBI] | ||||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces |
Protein attributes
| Sequence length | 241 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at protein level |
General annotation (Comments)
| Function | Required for normal levels of gene conversion events during meiosis. Ref.8 |
| Subcellular location | |
| Post-translational modification | Sumoylated. Ref.7 |
| Miscellaneous | Present with 1820 molecules/cell in log phase SD medium. Ref.6 |
| Sequence similarities | Belongs to the RMR1 family. |
| Sequence caution | The sequence CAA64137.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened. The sequence CAA96970.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Meiosis |
| Cellular component | Cytoplasm Nucleus |
| PTM | Ubl conjugation |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological process | meiotic gene conversion Inferred from mutant phenotype Ref.8. Source: SGD reciprocal meiotic recombinationInferred from mutant phenotype Ref.8. Source: SGD |
| Cellular component | cytoplasm Inferred from direct assay Ref.5. Source: SGD nucleusInferred from direct assay Ref.5. Source: SGD |
| Complete GO annotation... | |
Binary interactions
With | Entry | #Exp. | IntAct | Notes |
|---|---|---|---|---|
| AVO2 | Q04749 | 1 | EBI-24228,EBI-28131 |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 241 | 241 | Reduced meiotic recombination protein 1 | PRO_0000202705 | |||
Sequences
| ||||||||||||||||||
References
| « Hide 'large scale' references | |
| [1] | "Sequence of a 39,411 bp DNA fragment covering the left end of chromosome VII of Saccharomyces cerevisiae." Coissac E., Maillier E., Robineau S., Netter P. Yeast 12:1555-1562(1996) [PubMed: 8972578] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 96604 / S288c / FY1679. |
| [2] | "The nucleotide sequence of Saccharomyces cerevisiae chromosome VII." Tettelin H., Agostoni-Carbone M.L., Albermann K., Albers M., Arroyo J., Backes U., Barreiros T., Bertani I., Bjourson A.J., Brueckner M., Bruschi C.V., Carignani G., Castagnoli L., Cerdan E., Clemente M.L., Coblenz A., Coglievina M., Coissac E. Kleine K.Nature 387:81-84(1997) [PubMed: 9169869] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 96604 / S288c / FY1679. |
| [3] | Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c. |
| [4] | "Sequencing and comparison of yeast species to identify genes and regulatory elements." Kellis M., Patterson N., Endrizzi M., Birren B.W., Lander E.S. Nature 423:241-254(2003) [PubMed: 12748633] [Abstract] Cited for: IDENTIFICATION OF PROBABLE INITIATION SITE. |
| [5] | "Global analysis of protein localization in budding yeast." Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K. Nature 425:686-691(2003) [PubMed: 14562095] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS]. |
| [6] | "Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed: 14562106] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS]. |
| [7] | "Defining the SUMO-modified proteome by multiple approaches in Saccharomyces cerevisiae." Hannich J.T., Lewis A., Kroetz M.B., Li S.J., Heide H., Emili A., Hochstrasser M. J. Biol. Chem. 280:4102-4110(2005) [PubMed: 15590687] [Abstract] Cited for: SUMOYLATION. |
| [8] | "Novel roles for selected genes in meiotic DNA processing." Jordan P.W., Klein F., Leach D.R. PLoS Genet. 3:E222-E222(2007) [PubMed: 18069899] [Abstract] Cited for: FUNCTION. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | X94357 Genomic DNA. Translation: CAA64137.1. Different initiation. Z72772 Genomic DNA. Translation: CAA96970.1. Different initiation. BK006941 Genomic DNA. Translation: DAA07869.1. |
| PIR | S61611. |
| RefSeq | NP_011264.2. NM_001181116.1. |
3D structure databases | |
| ProteinModelPortal | P53060. |
| ModBase | Search... |
Protein-protein interaction databases | |
| DIP | DIP-4375N. |
| IntAct | P53060. 6 interactions. |
| MINT | MINT-477238. |
| STRING | P53060. |
Proteomic databases | |
| PeptideAtlas | P53060. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblFungi | YGL250W; YGL250W; YGL250W. |
| GeneID | 852642. |
| KEGG | sce:YGL250W. |
| NMPDR | fig|4932.3.peg.2367. |
Organism-specific databases | |
| CYGD | YGL250w. |
| SGD | S000003219. RMR1. |
Phylogenomic databases | |
| eggNOG | fuNOG10883. |
| HOGENOM | HBG204290. |
| OMA | PRFVSRY. |
| OrthoDB | EOG4WWVVF. |
Gene expression databases | |
| ArrayExpress | P53060. |
| Genevestigator | P53060. |
| GermOnline | YGL250W. Saccharomyces cerevisiae. |
Family and domain databases | |
| InterPro | IPR018822. UPF0646. [Graphical view] |
| Pfam | PF10336. DUF2420. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Other | |
| NextBio | 971897. |
Entry information
| Entry name | RMR1_YEAST | ||||||||
| Accession | Primary (citable) accession number: P53060 Secondary accession number(s): D6VV85 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Fungal Protein Annotation Program | ||||||||
Relevant documents
| Yeast Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD |
| Yeast chromosome VII Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names |
| Uncharacterized protein families (UPF) List of uncharacterized protein family (UPF) entries |
| SIMILARITY comments Index of protein domains and families |

Clusters with