Reviewed, UniProtKB/Swiss-Prot P53058 (VEL1_YEAST)

Names and origin

Protein names

Recommended name:
    Protein VEL1
Alternative name(s):
    Velum formation protein 1

Gene names

Name:	VEL1
Ordered Locus Names:	YGL258W
ORF Names:	NRA206

Organism

Saccharomyces cerevisiae (Baker's yeast) [Complete proteome]

Taxonomic identifier

4932 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	206 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Subcellular location	Cytoplasm › cytosol By similarity. Note: Intracellular soluble fraction By similarity.
Induction	In zinc-depleted conditions and has increased expression in NAP1 deletion mutants. Ref.3 Ref.5
Sequence similarities	Belongs to the VEL1 family.

Ontologies

Keywords
Cellular component	Cytoplasm
Domain	Signal
Ligand	Zinc
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytosol Inferred from electronic annotation. Source: UniProtKB-SubCell soluble fraction Ref.4 Inferred from direct assay. Source: SGD
Molecular function	zinc ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 19	19	Potential
	Chain	20 – 206	187	Protein VEL1		PRO_0000202704

Sequences

	Sequence		Length	Mass (Da)
	P53058-1 [UniParc]. Last modified October 1, 1996. Version 1. Checksum: D4DB805E578CCA2B	FASTA	206	22,152
	10 20 30 40 50 60 MSFLSIFTFF SVLISVATTV RFDLTNVTCK GLHGPHCGTY VMEVVGQNGT FLGQSTFVGA 70 80 90 100 110 120 DVLTESAGDA WARYLGQETR FLPKLTTIAS NETKNFSPLI FTTNINTCNP QSIGDAMVPF 130 140 150 160 170 180 ANTVTGEIEY NSWADTADNA SFITGLANQL FNSTDYGVQV ASCYPNFASV ILSTPAVNIF 190 200 GKDDTLPDYC TAIQLKAVCP PEAGFD

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence of a 39,411 bp DNA fragment covering the left end of chromosome VII of Saccharomyces cerevisiae." Coissac E., Maillier E., Robineau S., Netter P. Yeast 12:1555-1562(1996) [PubMed: 8972578] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 96604 / S288c / FY1679.
[2]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome VII." Tettelin H., Agostoni-Carbone M.L., Albermann K., Albers M., Arroyo J., Backes U., Barreiros T., Bertani I., Bjourson A.J., Brueckner M., Bruschi C.V., Carignani G., Castagnoli L., Cerdan E., Clemente M.L., Coblenz A., Coglievina M., Coissac E. , Defoor E., Del Bino S., Delius H., Delneri D., de Wergifosse P., Dujon B., Durand P., Entian K.-D., Eraso P., Escribano V., Fabiani L., Fartmann B., Feroli F., Feuermann M., Frontali L., Garcia-Gonzalez M., Garcia-Saez M.I., Goffeau A., Guerreiro P., Hani J., Hansen M., Hebling U., Hernandez K., Heumann K., Hilger F., Hofmann B., Indge K.J., James C.M., Klima R., Koetter P., Kramer B., Kramer W., Lauquin G., Leuther H., Louis E.J., Maillier E., Marconi A., Martegani E., Mazon M.J., Mazzoni C., McReynolds A.D.K., Melchioretto P., Mewes H.-W., Minenkova O., Mueller-Auer S., Nawrocki A., Netter P., Neu R., Nombela C., Oliver S.G., Panzeri L., Paoluzi S., Plevani P., Portetelle D., Portillo F., Potier S., Purnelle B., Rieger M., Riles L., Rinaldi T., Robben J., Rodrigues-Pousada C., Rodriguez-Belmonte E., Rodriguez-Torres A.M., Rose M., Ruzzi M., Saliola M., Sanchez-Perez M., Schaefer B., Schaefer M., Scharfe M., Schmidheini T., Schreer A., Skala J., Souciet J.-L., Steensma H.Y., Talla E., Thierry A., Vandenbol M., van der Aart Q.J.M., Van Dyck L., Vanoni M., Verhasselt P., Voet M., Volckaert G., Wambutt R., Watson M.D., Weber N., Wedler E., Wedler H., Wipfli P., Wolf K., Wright L.F., Zaccaria P., Zimmermann M., Zollner A., Kleine K. Nature 387:81-84(1997) [PubMed: 9169869] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 96604 / S288c / FY1679.
[3]	"Genome-wide expression analysis of NAP1 in Saccharomyces cerevisiae." Ohkuni K., Shirahige K., Kikuchi A. Biochem. Biophys. Res. Commun. 306:5-9(2003) [PubMed: 12788058] [Abstract] Cited for: INDUCTION.
[4]	"Sequence-based approach for identification of cell wall proteins in Saccharomyces cerevisiae." Terashima H., Fukuchi S., Nakai K., Arisawa M., Hamada K., Yabuki N., Kitada K. Curr. Genet. 40:311-316(2002) [PubMed: 11935221] [Abstract] Cited for: SUBCELLULAR LOCATION.
[5]	"Application of genome-wide expression analysis to identify molecular markers useful in monitoring industrial fermentations." Higgins V.J., Rogers P.J., Dawes I.W. Appl. Environ. Microbiol. 69:7535-7540(2003) [PubMed: 14660410] [Abstract] Cited for: INDUCTION BY ZINC DEPLETION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	X94357 Genomic DNA. Translation: CAA64129.1. Z72780 Genomic DNA. Translation: CAA96978.1.
PIR	S61603.
RefSeq	NP_011256.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
DIP	DIP:4876N.
IntAct	P53058. 2 interactions.
STRING	P53058.
Genome annotation databases
Ensembl	YGL258W; YGL258W; YGL258W; Saccharomyces cerevisiae. [Genome view]
GeneID	852634.
GenomeReviews	Gene locus YGL258W in contig Y13135_GR.
KEGG	sce:YGL258W.
NMPDR	fig|4932.3.peg.2359.
Organism-specific databases
CYGD	YGL258w.
SGD	S000003227. VEL1.
Phylogenomic databases
HOGENOM	P53058.
OMA	TIASNET.
Gene expression databases
ArrayExpress	P53058.
Genevestigator	P53058.
GermOnline	YGL258W. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR019435. Velum_formation_protein. [Graphical view]
Pfam	PF10339. Vel1p. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	971873.

Entry information

Entry name

VEL1_YEAST

Accession

Primary (citable) accession number: P53058

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1996
Last sequence update:	October 1, 1996
Last modified:	November 3, 2009
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)