Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

P52983 (G6PI_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 89. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:slr1349
OrganismSynechocystis sp. (strain PCC 6803 / Kazusa) [Reference proteome] [HAMAP]
Taxonomic identifier1111708 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis

Protein attributes

Sequence length531 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 531531Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000180755

Sites

Active site3241Proton donor By similarity
Active site3531 By similarity
Active site4571 By similarity

Sequences

Sequence LengthMass (Da)Tools
P52983 [UniParc].

Last modified October 1, 1996. Version 1.
Checksum: ABD5AA851C0BEF48

FASTA53158,356
        10         20         30         40         50         60 
MNNQQLWQRY QDWLYYHGGL DFYLDVSRMG FSDALVEDLQ PKFAKAFQDM VALEKGAIAN 

        70         80         90        100        110        120 
PDEQRMVGHY WLRNPALAPN DGIRAEITEP LRQIKAFVAD VHQGNIKPPT APKFTDLLAI 

       130        140        150        160        170        180 
GIGGSALGPQ FVAQALAPNF PPLAIHFIDN SDPDGIDRVL NCLKAQDKLK STLVVTTSKS 

       190        200        210        220        230        240 
GGTPEPRNGL AETKAVFEAQ GLHFADYAVA VTMPGSKLSQ QAQTEQWLQA FPMQDWVGGR 

       250        260        270        280        290        300 
TSELSAVGLL PAALQGIDIQ AMLDGAKTMD EATRVRELRQ NPAALLALAW YYAGDGQGKK 

       310        320        330        340        350        360 
DMVILPYKDR LLLFSRYLQQ LVMESLGKER DLDGNVVHQG IAVYGNKGST DQHAYVQQLR 

       370        380        390        400        410        420 
DGVPNFFATF IEVLHDRQGP SLELEPGVTS GDYLSGFLQG TRQALFENQR DSITVTIPEV 

       430        440        450        460        470        480 
DATSVGALIA LYERAVSFYG SLVNVNAYHQ PGVEAGKKAA ASILELQKAI LSTLQNESGP 

       490        500        510        520        530 
IALEALATKV QAPEQVETVY KIVRHLAAND RGVTLQGDRQ FPQRLQIQWR S 

« Hide

References

« Hide 'large scale' references
[1]"Sequence analysis of a DNA fragment from Synechocystis PCC6803 containing genes homologous to cysE (serine acetyltransferase) and pgi (glucose-6-phosphate isomerase)."
Sakamoto T., Wada H., Nishida I., Ohta H., Murata N.
Plant Mol. Biol. 29:187-187(1995)
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. expand/collapse author list , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 6803 / Kazusa.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
D13777 Genomic DNA. Translation: BAA02920.1.
BA000022 Genomic DNA. Translation: BAA18168.1.
PIRS75607.
RefSeqNP_441488.1. NC_000911.1.
YP_005651546.1. NC_017277.1.
YP_007451370.1. NC_020286.1.

3D structure databases

ProteinModelPortalP52983.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActP52983. 2 interactions.
STRING1148.slr1349.

Proteomic databases

PaxDbP52983.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAA18168; BAA18168; BAA18168.
GeneID12254198.
14617030.
954868.
KEGGsyn:slr1349.
syy:SYNGTS_1593.
syz:MYO_116080.
PATRIC23840391. VBISynSp132158_1753.

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000131425.
KOK01810.
OMARQVGHYW.
OrthoDBEOG64R61J.
PhylomeDBP52983.
ProtClustDBPRK14096.

Enzyme and pathway databases

UniPathwayUPA00109; UER00181.

Family and domain databases

HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 2 hits.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_SYNY3
AccessionPrimary (citable) accession number: P52983
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: April 16, 2014
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Synechocystis PCC 6803

Synechocystis (strain PCC 6803): entries and gene names

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways