Reviewed, UniProtKB/Swiss-Prot P52972 (MURI_BACSH)

Names and origin

Protein names

Recommended name:
    Glutamate racemase
    EC=5.1.1.3

Gene names

Name:	murI
Synonyms:	glr

Organism

Bacillus sphaericus

Taxonomic identifier

1421 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Planococcaceae › Lysinibacillus

Protein attributes

Sequence length	265 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Provides the (R)-glutamate required for cell wall biosynthesis By similarity.
Catalytic activity	L-glutamate = D-glutamate. HAMAP MF_00258
Pathway	Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00258
Sequence similarities	Belongs to the aspartate/glutamate racemases family.

Ontologies

Keywords
Biological process	Cell shape Cell wall biogenesis/degradation Peptidoglycan synthesis
Molecular function	Isomerase
Gene Ontology (GO)
Biological process	cell wall organization Inferred from electronic annotation. Source: UniProtKB-KW peptidoglycan biosynthetic process Inferred from electronic annotation. Source: HAMAP regulation of cell shape Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	glutamate racemase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 265	265	Glutamate racemase HAMAP MF_00258		PRO_0000095452

Sequences

	Sequence		Length	Mass (Da)
	P52972-1 [UniParc]. Last modified October 1, 1996. Version 1. Checksum: 85B4CB94D602BA3E	FASTA	265	29,059
	10 20 30 40 50 60 MNAPIGVIDS GVGGLTVAKE IIKRLPNETI YYIGDTARCP YGPRTRQEVR NFTWQMAKAL 70 80 90 100 110 120 EKMNIKMLVI ACNTATAVAL ESLQRNMPFP VLGVINRGAR AAVKKTKRHE VVVLATEGTI 130 140 150 160 170 180 KSGAYEEALL SLNTSTHIIP LACPTFVPLV ESGEYKGQFA NNLIAEGLKP LKNEQFDTVI 190 200 210 220 230 240 LGCTHYPILQ KQIEAVVGED VFVLSSAEET AKDVEEMLAY NGTLADTNAK PAHKFYATGS 250 260 VPIFRSIAEN WLEQGTLDIH RITLK

References

[1]

"Characterization of the genes encoding D-amino acid transaminase and glutamate racemase, two D-glutamate biosynthetic enzymes of Bacillus sphaericus ATCC 10208." Fotheringham I.G., Bledig S.A., Taylor P.P. J. Bacteriol. 180:4319-4323(1998) [PubMed: 9696787] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 10208 / NRS 966 / NCIB 11935 / 1911.

Cross-references

Sequence databases
EMBLGenBankDDBJ	U26733 Genomic DNA. Translation: AAA68029.1.
3D structure databases
HSSP	HSSP built from PDB template 1B74 based on UniProtKB P56868.
ModBase	Search...
Enzyme and pathway databases
BRENDA	5.1.1.3. 327.
Family and domain databases
HAMAP	MF_00258. [Tree]
InterPro	IPR015942. Asp/Glu/hydantoin_racemase. IPR001920. Asp/Glu_race. IPR018187. Asp/Glu_racemase_AS. IPR004391. Glu_race. [Graphical view]
Gene3D	G3DSA:3.40.50.1860. Asp/Glu_race. 1 hit.
Pfam	PF01177. Asp_Glu_race. 1 hit. [Graphical view]
TIGRFAMs	TIGR00067. glut_race. 1 hit.
PROSITE	PS00923. ASP_GLU_RACEMASE_1. 1 hit. PS00924. ASP_GLU_RACEMASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

MURI_BACSH

Accession

Primary (citable) accession number: P52972

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1996
Last sequence update:	October 1, 1996
Last modified:	September 22, 2009
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)