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Protein

Protein MSN5

Gene

MSN5

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Miscellaneous

Present with 3500 molecules/cell in log phase SD medium.1 Publication

GO - Molecular functioni

  • nuclear export signal receptor activity Source: SGD
  • RNA binding Source: GO_Central

GO - Biological processi

  • protein export from nucleus Source: SGD
  • regulation of protein export from nucleus Source: GO_Central
  • tRNA re-export from nucleus Source: SGD

Enzyme and pathway databases

BioCyciYEAST:G3O-29891-MONOMER.

Protein family/group databases

TCDBi9.A.50.1.1. the nuclear t-rna exporter (t-exporter) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein MSN5
Gene namesi
Name:MSN5
Ordered Locus Names:YDR335W
ORF Names:D9651.5
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome IV

Organism-specific databases

EuPathDBiFungiDB:YDR335W.
SGDiS000002743. MSN5.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: SGD
  • nucleus Source: SGD
  • RNA nuclear export complex Source: GO_Central

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000965991 – 1224Protein MSN5Add BLAST1224

Proteomic databases

MaxQBiP52918.
PRIDEiP52918.

Interactioni

Subunit structurei

Interacts with CEX1.1 Publication

Protein-protein interaction databases

BioGridi32392. 386 interactors.
DIPiDIP-1459N.
IntActiP52918. 24 interactors.
MINTiMINT-388409.
STRINGi4932.YDR335W.

Structurei

3D structure databases

ProteinModelPortaliP52918.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00390000013979.
HOGENOMiHOG000248154.
InParanoidiP52918.
KOiK14289.
OMAiPERHAFL.
OrthoDBiEOG092C08R2.

Family and domain databases

Gene3Di1.25.10.10. 1 hit.
InterProiView protein in InterPro
IPR011989. ARM-like.
IPR016024. ARM-type_fold.
SUPFAMiSSF48371. SSF48371. 5 hits.

Sequencei

Sequence statusi: Complete.

P52918-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSTGASQIV SALDVIYSPK SNNSQRQEAQ KFLDEVKLCS ESPFWGYEIA
60 70 80 90 100
LQNPTNSILK YFGLGLLDHA VKKNWNDYDE GKRVALRKWV MELNFGVQDY
110 120 130 140 150
DTRYIKEKLA TLWVEVAKRT WGEALKQTNP TEEQLLTSWV DMDNNLFELW
160 170 180 190 200
NINQSSRELA LIIFRILFED VFLLDDLIVL KRMTVIQPLC VMIVCPIEVF
210 220 230 240 250
AIKYKFSDKW TKFKANEEGW FSVWIPELNN ALQQNNSEYI IRLLETLKTC
260 270 280 290 300
LNWPLTEVIV RNDVLSSLLT CLSSNIPRAQ SMALDSIHIL LTRPYSNESH
310 320 330 340 350
YQMTIDRVFD NMDLLDSVYE SLLFDPTDDI DETKYPIIKK FVDMISCLYV
360 370 380 390 400
CVPKIKETNG QIQKYFKLVL KTTYNPSLIV SGLTLDLWCT CLRNDEYLPK
410 420 430 440 450
LEKYVIPDLL QFAADALVYY EQIDGHISKK FAEIDFQSKS EFQTFCSTYR
460 470 480 490 500
KRIRDIIRLI SCVELDLTYD WLNNRLNNYF SSPFGQQVLS STFLDHKLEP
510 520 530 540 550
YLGALSQYMI VECFINGCIR WKIWYPTGDD YDEKLDSILQ KLEILSNQLI
560 570 580 590 600
ALNLREPLLL KKQIQNFALF LTMLKDNVLF TLLEKIITSA TMDYPEINLE
610 620 630 640 650
ERGAESDAVR DLRYACGIEL NRMALLMPES LKKIYPDLES VIARIMPNLS
660 670 680 690 700
YHEKISFKSF LLIIVLKSSL DMKEERFAAI VDPELLAWSD KTTVVGLSDL
710 720 730 740 750
HWFMERLGIV QIAEYFQRRD IDENSDLLSI PIDDEGKELK SELTKRWQSL
760 770 780 790 800
FPVRATRMFI HYSMQSIKTD EEFKMLQDLW RPRIVPILPY ITRLLYQLQS
810 820 830 840 850
YHDPDNWKGL PTVVQSFVKY STIERFWEAG ASNKSKDEFI DEHMKAMQTL
860 870 880 890 900
RDFADSVGHI IRYTREYTLL VLSAISSLGS VFYLLDESPD LLLNSIAIFK
910 920 930 940 950
PGSNEISPGV STHGWKHIMN IAIRPILKGC PKDCLGKFMP AFLPKLFEIL
960 970 980 990 1000
DLLLCQKWSS HMNDMDMNPV PTDDDQMTEE ILEENLLRQL TTVVVRIVID
1010 1020 1030 1040 1050
CVGQGNANPN SAKSRLNNHQ MEMRKIIFND LNTLAPFLKL LNHLISFKDT
1060 1070 1080 1090 1100
KCSFNSILVM KCCLTSVLNQ NNTVDEYFTF EVMKNLLLNV LCNSAFKDSF
1110 1120 1130 1140 1150
HEALYAFTVI FLTLCKEYPS ARAFLFEISN GYNIDELYRN LRSVDEYKTQ
1160 1170 1180 1190 1200
RALMIDFIDW VKSTSGKEDG NVDHAGDERK RQEKREAILK KANERLIKKN
1210 1220
KENGDMLDDP NIEDGAVGNL FDDN
Length:1,224
Mass (Da):142,118
Last modified:October 1, 1996 - v1
Checksum:iC47A6767CBA44486
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti886D → G in CAA63705 (Ref. 1) Curated1
Sequence conflicti1011S → R in CAA63705 (Ref. 1) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X93302 mRNA. Translation: CAA63705.1.
U51032 Genomic DNA. Translation: AAB64771.1.
BK006938 Genomic DNA. Translation: DAA12177.1.
PIRiS70100.
RefSeqiNP_010622.1. NM_001180643.1.

Genome annotation databases

EnsemblFungiiYDR335W; YDR335W; YDR335W.
GeneIDi851935.
KEGGisce:YDR335W.

Similar proteinsi

Entry informationi

Entry nameiMSN5_YEAST
AccessioniPrimary (citable) accession number: P52918
Secondary accession number(s): D6VSW7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: July 5, 2017
This is version 119 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome IV
    Yeast (Saccharomyces cerevisiae) chromosome IV: entries and gene names