P52913 (NTP4_TOXGO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative nucleoside-triphosphatase
Short name=NTPase
EC=3.6.1.15

Alternative name(s):
Nucleoside triphosphate phosphohydrolase

Gene names

Name:

NTP4

Organism

Toxoplasma gondii

Taxonomic identifier

5811 [NCBI]

Taxonomic lineage

Eukaryota › Alveolata › Apicomplexa › Coccidia › Eucoccidiorida › Eimeriorina › Sarcocystidae › Toxoplasma

Protein attributes

Sequence length	592 AA.
Sequence status	Complete.
Protein existence	Uncertain

General annotation (Comments)

Catalytic activity	NTP + H2O = NDP + phosphate.
Sequence similarities	Belongs to the GDA1/CD39 NTPase family.
Caution	Could be the product of a pseudogene. It does not seem to start with an initiator Met.
Sequence caution	The sequence AAA80336.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Molecular function	Hydrolase
Gene Ontology (GO)
Cellular component	extracellular region Inferred from electronic annotation. Source: InterPro
Molecular function	nucleoside-triphosphatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 592	592	Putative nucleoside-triphosphatase		PRO_0000209922
Sites
	Active site	200	1	Proton acceptor By similarity

Sequences

	Sequence		Length	Mass (Da)
	P52913 [UniParc]. Last modified November 1, 1997. Version 2. Checksum: B0C4014049F8D79B	FASTA	592	65,762
	10 20 30 40 50 60 LPEKRINVGK KHLQTLRNLE TRCHDSFQAF VVIDARSSST RTNVFLAKTR SCPNRGRSID 70 80 90 100 110 120 PDSIRLIREG KRFTGLRVVL EEWLDTYAGK DWESRPVDAR LLFQYVPQMH EGAKKPMQLL 130 140 150 160 170 180 EEDTVAILDS QLNEKQKVQV KALGIPAMLC STAGVRDFHE WYRDALFVLL RHLINNPSPA 190 200 210 220 230 240 HGYKFFTNPF WTRPITGAEE GLFAFITLNH LSRRLGEDPA RCMIDEYGVK QCRNDLAGVV 250 260 270 280 290 300 EVGGASAQIV FPLQEGTVLP SSVRAVNLQR ERLLPERYPS ADVVSVSFMQ LGMASSAGLF 310 320 330 340 350 360 LKELCSNDEF LQGGICSNPC LFKGFQQSCS AGEVEVRPDG SASVNEDVRK NRLKPLATYC 370 380 390 400 410 420 SVNNPEISFK VTNEMQCREN SIDPTKPLAE RMKIENCSII KGTGNFDKCV SQVESILVAP 430 440 450 460 470 480 KLPLPANIEA ASSGFESVDQ VFRFASSTAP MIVTGGGMLA AINTLKDHRL LRSDFSGDVE 490 500 510 520 530 540 ELAEAAREFC SSEVIIRTDG PVIQLPNARG EQKLNSLNFD LCKTMALTVS LLRHMAAGEN 550 560 570 580 590 QPSFIKWEKS IAGPDGKPLA DLGWQVGVIL HHVLFTEEWG RNAYEAGYSH NL

References

[1]	Cote S., Morency M., Levesque R.C. Submitted (NOV-1995) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: Nicole.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U28353 Genomic DNA. Translation: AAA80336.1. Different initiation.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR000407. GDA1_CD39_NTPase. IPR017227. NTPase_alveloata. [Graphical view]
Pfam	PF01150. GDA1_CD39. 1 hit. [Graphical view]
PIRSF	PIRSF037506. NTPase. 1 hit.
PROSITE	PS01238. GDA1_CD39_NTPASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

NTP4_TOXGO

Accession

Primary (citable) accession number: P52913

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1996
Last sequence update:	November 1, 1997
Last modified:	September 21, 2011
This is version 43 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)