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Protein

60S ribosomal protein L5-A

Gene

rpl501

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

This protein binds 5S RNA.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

RNA-binding, rRNA-binding

Enzyme and pathway databases

ReactomeiR-SPO-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-SPO-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-SPO-72689. Formation of a pool of free 40S subunits.
R-SPO-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-SPO-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-SPO-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L5-A
Gene namesi
Name:rpl501
Synonyms:rpl5a
ORF Names:SPAC3H5.12c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC3H5.12c.
PomBaseiSPAC3H5.12c. rpl501.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001314521 – 29460S ribosomal protein L5-AAdd BLAST294

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei10Phosphoserine1 Publication1
Modified residuei12Phosphotyrosine1 Publication1
Modified residuei81Phosphoserine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiP52822.
PRIDEiP52822.

PTM databases

iPTMnetiP52822.

Interactioni

Protein-protein interaction databases

BioGridi280056. 3 interactors.
IntActiP52822. 1 interactor.
MINTiMINT-4783846.

Structurei

3D structure databases

ProteinModelPortaliP52822.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L18P family.Curated

Phylogenomic databases

HOGENOMiHOG000105947.
InParanoidiP52822.
KOiK02932.
OMAiMAAYSHE.
OrthoDBiEOG092C44EY.
PhylomeDBiP52822.

Family and domain databases

HAMAPiMF_01337_A. Ribosomal_L18_A. 1 hit.
InterProiIPR005485. Rbsml_L5_euk/L18_arc.
IPR025607. Rbsml_L5e/L18P_C.
[Graphical view]
PANTHERiPTHR23410. PTHR23410. 1 hit.
PfamiPF14204. Ribosomal_L18_c. 1 hit.
PF17144. Ribosomal_L5e. 1 hit.
[Graphical view]
PRINTSiPR00058. RIBOSOMALL5.

Sequencei

Sequence statusi: Complete.

P52822-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPFIKAVKSS PYFSRYQTKY RRRREGKTDY YARKRLIAQA KNKYNAPKYR
60 70 80 90 100
LVVRFSNRFV TCQIVSSRVN GDYVLAHAHS SELPRYGIKW GLANWTAAYA
110 120 130 140 150
TGLLVARRAL AKVGLADKYE GVTEPEGEFE LTEAIEDGPR PFKVFLDVGL
160 170 180 190 200
KRTSTGSRVF GAMKGASDGG LFIPHSPNRF PGFDIETEEL DDETLRKYIY
210 220 230 240 250
GGHVAEYMEM LIDDDEERYQ KQFSGLIADG IESDQLEDIY AEAYAKIRED
260 270 280 290
PSFQKSGKDA AAFKAESLKH TQRKLTAEER KERFNAKVIE AGRA
Length:294
Mass (Da):33,460
Last modified:July 15, 1998 - v2
Checksum:iCA72FE578EB3E35F
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti24Missing in AAB05674 (PubMed:8626719).Curated1
Sequence conflicti28T → I in AAB05674 (PubMed:8626719).Curated1
Sequence conflicti223F → S in AAB05674 (PubMed:8626719).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U48270 Genomic DNA. Translation: AAB05674.1.
CU329670 Genomic DNA. Translation: CAB16596.1.
PIRiT38758.
RefSeqiNP_594180.1. NM_001019604.2.

Genome annotation databases

EnsemblFungiiSPAC3H5.12c.1; SPAC3H5.12c.1:pep; SPAC3H5.12c.
GeneIDi2543642.
KEGGispo:SPAC3H5.12c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U48270 Genomic DNA. Translation: AAB05674.1.
CU329670 Genomic DNA. Translation: CAB16596.1.
PIRiT38758.
RefSeqiNP_594180.1. NM_001019604.2.

3D structure databases

ProteinModelPortaliP52822.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi280056. 3 interactors.
IntActiP52822. 1 interactor.
MINTiMINT-4783846.

PTM databases

iPTMnetiP52822.

Proteomic databases

MaxQBiP52822.
PRIDEiP52822.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPAC3H5.12c.1; SPAC3H5.12c.1:pep; SPAC3H5.12c.
GeneIDi2543642.
KEGGispo:SPAC3H5.12c.

Organism-specific databases

EuPathDBiFungiDB:SPAC3H5.12c.
PomBaseiSPAC3H5.12c. rpl501.

Phylogenomic databases

HOGENOMiHOG000105947.
InParanoidiP52822.
KOiK02932.
OMAiMAAYSHE.
OrthoDBiEOG092C44EY.
PhylomeDBiP52822.

Enzyme and pathway databases

ReactomeiR-SPO-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-SPO-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-SPO-72689. Formation of a pool of free 40S subunits.
R-SPO-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-SPO-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-SPO-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Miscellaneous databases

PROiP52822.

Family and domain databases

HAMAPiMF_01337_A. Ribosomal_L18_A. 1 hit.
InterProiIPR005485. Rbsml_L5_euk/L18_arc.
IPR025607. Rbsml_L5e/L18P_C.
[Graphical view]
PANTHERiPTHR23410. PTHR23410. 1 hit.
PfamiPF14204. Ribosomal_L18_c. 1 hit.
PF17144. Ribosomal_L5e. 1 hit.
[Graphical view]
PRINTSiPR00058. RIBOSOMALL5.
ProtoNetiSearch...

Entry informationi

Entry nameiRL5A_SCHPO
AccessioniPrimary (citable) accession number: P52822
Secondary accession number(s): O14153
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: July 15, 1998
Last modified: November 30, 2016
This is version 115 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

There are two genes for L5 in S.pombe.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.