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P52783

- GLNA_PINSY

UniProt

P52783 - GLNA_PINSY

Protein

Glutamine synthetase cytosolic isozyme

Gene
N/A
Organism
Pinus sylvestris (Scots pine)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 63 (01 Oct 2014)
      Sequence version 1 (01 Oct 1996)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine.

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. glutamate-ammonia ligase activity Source: UniProtKB-EC

    GO - Biological processi

    1. glutamine biosynthetic process Source: InterPro

    Keywords - Molecular functioni

    Ligase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glutamine synthetase cytosolic isozyme (EC:6.3.1.2)
    Alternative name(s):
    GS1
    Glutamate--ammonia ligase
    OrganismiPinus sylvestris (Scots pine)
    Taxonomic identifieri3349 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaPinidaePinalesPinaceaePinusPinus

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 357357Glutamine synthetase cytosolic isozymePRO_0000153195Add
    BLAST

    Interactioni

    Subunit structurei

    Homooctamer.By similarity

    Structurei

    3D structure databases

    ProteinModelPortaliP52783.
    SMRiP52783. Positions 5-356.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glutamine synthetase family.Curated

    Family and domain databases

    Gene3Di3.10.20.70. 1 hit.
    3.30.590.10. 1 hit.
    InterProiIPR008147. Gln_synt_beta.
    IPR014746. Gln_synth/guanido_kin_cat_dom.
    IPR008146. Gln_synth_cat_dom.
    IPR027303. Gln_synth_gly_rich_site.
    IPR027302. Gln_synth_N_conserv_site.
    [Graphical view]
    PfamiPF00120. Gln-synt_C. 1 hit.
    PF03951. Gln-synt_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF54368. SSF54368. 1 hit.
    PROSITEiPS00180. GLNA_1. 1 hit.
    PS00181. GLNA_ATP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P52783-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSSVLTDLLN LDLSDVTEKV IAEYIWIGGS GMDMRSKARS LSGPVSSVKE    50
    LPKWNYDGSS TGQAQGHDSE VILYPQAIFR DPFRRGKHIL VICDAYSPNG 100
    TAIPSNKRAA AAKIFNEKAV SDEETWYGLE QEYTLLQKDV KWPLGWPIGG 150
    YPGPQGPYYC GVGADKAWGR DIVDAHYKAC LYSGINISGI NGEVMPGQWE 200
    FQVGPSVGIS AADELWCARF IMERITEKAG VVLSFDPKPI EGDWNGAGCH 250
    TNYSTKSMRK EGGFEVIKKA IEKLKLRHKE HISAYGEGNE RRLTGRHETA 300
    DMNTFSWGVA NRGASVRVGR DTEKEGKGYF EDRRPASNMD PYIVTSMIAE 350
    TTILWKP 357
    Length:357
    Mass (Da):39,571
    Last modified:October 1, 1996 - v1
    Checksum:i659B457032DB9F11
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti183 – 1831S → A in CAA52448. (PubMed:7506600)Curated
    Sequence conflicti307 – 3071W → R in CAA52448. (PubMed:7506600)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X69822 mRNA. Translation: CAA49476.1.
    X74429 mRNA. Translation: CAA52448.1.
    PIRiS36195.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X69822 mRNA. Translation: CAA49476.1 .
    X74429 mRNA. Translation: CAA52448.1 .
    PIRi S36195.

    3D structure databases

    ProteinModelPortali P52783.
    SMRi P52783. Positions 5-356.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 3.10.20.70. 1 hit.
    3.30.590.10. 1 hit.
    InterProi IPR008147. Gln_synt_beta.
    IPR014746. Gln_synth/guanido_kin_cat_dom.
    IPR008146. Gln_synth_cat_dom.
    IPR027303. Gln_synth_gly_rich_site.
    IPR027302. Gln_synth_N_conserv_site.
    [Graphical view ]
    Pfami PF00120. Gln-synt_C. 1 hit.
    PF03951. Gln-synt_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54368. SSF54368. 1 hit.
    PROSITEi PS00180. GLNA_1. 1 hit.
    PS00181. GLNA_ATP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Molecular characterization of a cDNA clone encoding glutamine synthetase from a gymnosperm, Pinus sylvestris."
      Canton F.R., Garcia-Gutierrez A., Gallardo F., de Vicente A., Canovas F.M.
      Plant Mol. Biol. 22:819-828(1993) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    2. "Coaction of blue light and light absorbed by phytochrome in control of glutamine synthetase gene expression in Scots pine (Pinus sylvestris L.) seedlings."
      Elmlinger M.W., Bolle C., Batschauer A., Oelmueller R., Mohr H.
      Planta 192:189-194(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].

    Entry informationi

    Entry nameiGLNA_PINSY
    AccessioniPrimary (citable) accession number: P52783
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 1, 1996
    Last sequence update: October 1, 1996
    Last modified: October 1, 2014
    This is version 63 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Irreversibly inhibited by the herbicide L-phosphinothricin (PPT).

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3