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P52780 (SYQ_LUPLU) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 74. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutamine--tRNA ligase

EC=6.1.1.18
Alternative name(s):
Glutaminyl-tRNA synthetase
Short name=GlnRS
OrganismLupinus luteus (European yellow lupin)
Taxonomic identifier3873 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaeGenisteaeLupinus

Protein attributes

Sequence length794 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln).

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
Gene Ontology (GO)
   Biological_processglutaminyl-tRNA aminoacylation

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: InterPro

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

glutamine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 794794Glutamine--tRNA ligase
PRO_0000195864

Regions

Motif277 – 28711"HIGH" region
Motif505 – 5095"KMSKS" region

Sites

Binding site5081ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
P52780 [UniParc].

Last modified December 15, 1998. Version 2.
Checksum: 4C7D02C0795268E1

FASTA79490,483
        10         20         30         40         50         60 
MPAKDDTSSD KEKSLELFLK IGLDERTAKN TVANNKVTTN LTSVINDAGV TDGCSRTVGN 

        70         80         90        100        110        120 
LLYTVATKYP ANALPHRPTL LQYIVNSKVK TTAQLDAALS FLSATGSENL DLNKFEEACG 

       130        140        150        160        170        180 
VGVEVSTEDI KHAVDEVVEE NKATILELRY RVNVGELLGH VRKRLPWADA KVVKQLVDAK 

       190        200        210        220        230        240 
LYEILGDRTA ADNEKPKKKK EKPAKVEDKA APVATSEKPL EEDLNPYLIF PNPEDNFKVH 

       250        260        270        280        290        300 
TEVPFSDGNI LRCCNTKALL EKHLKATGGK VLTRFPPEPN GYLHIGHAKA MFVDFGLAKD 

       310        320        330        340        350        360 
RNGGCYLRFD DTNPEAEKKE YIDHIEEIVQ WMGWEPFKIT YTSNYFQELY EFAVELIRRG 

       370        380        390        400        410        420 
HAYVDHQTAD EIKEYREKKL NSPWRDRPIS ESLKLFEDMR RGFIEEGKAT LRMKQDMQSD 

       430        440        450        460        470        480 
NYNMYDLIAY RIKFTPHPHA GDKWCIYPSY DYAHCIVDSI ENVTHSLCTL EFETRRASYY 

       490        500        510        520        530        540 
WLLHALGIYQ PYVWEYSRLN VSNTVMSKRK LNRLVTEKWV DGWDDPRLMT LAGLRRRGMT 

       550        560        570        580        590        600 
PTAINAFVRG MGITRSDGTL ISVERLEYHV REELNKTAPR AMVVLHPLKV VITNLEAKSA 

       610        620        630        640        650        660 
IEVDAKKWPD AQADDASAFY KIPFSNVVYI ERSDFRMQDS KDYYGLAPGK SVILRYAFPI 

       670        680        690        700        710        720 
KCTEVILADD NETILEIRAE YDPSKKTKPK GVLHWVSQPS PGVDPLKVEV RLFERLFLSE 

       730        740        750        760        770        780 
NPAELDNWLG DLNPHSKVEI SNAYGVSLLK DAKLGDRFQF ERLGYFAVDQ DSTPEKLVFN 

       790 
RTVTLKDSYG KGGK 

« Hide

References

[1]"Isolation and characterization of a cDNA clone encoding a plant gene of aminoacyl-tRNA synthetase."
Siatecka M., Rozek M., Barciszewski J.
Plant Gene Register PGR95-103
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: cv. Ventus.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X91787 mRNA. Translation: CAA62901.1.
PIRT09643.

3D structure databases

ProteinModelPortalP52780.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D1.10.1160.10. 1 hit.
2.40.240.10. 2 hits.
3.40.50.620. 2 hits.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR004514. Gln-tRNA-synth.
IPR007638. Gln-tRNA-synth_Ib_RNA-bd_2.
IPR007639. Gln-tRNA-synth_Ib_RNA-bd_N.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERPTHR10119. PTHR10119. 1 hit.
PfamPF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
PF04558. tRNA_synt_1c_R1. 1 hit.
PF04557. tRNA_synt_1c_R2. 1 hit.
[Graphical view]
PRINTSPR00987. TRNASYNTHGLU.
SUPFAMSSF50715. SSF50715. 1 hit.
TIGRFAMsTIGR00440. glnS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYQ_LUPLU
AccessionPrimary (citable) accession number: P52780
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: December 15, 1998
Last modified: February 19, 2014
This is version 74 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries