Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Hydrophobin-1

Gene

hfb1

Organism
Hypocrea jecorina (Trichoderma reesei)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Contributes to surface hydrophobicity, which is important for processes such as association of hyphae in reproductive structures, dispersal of aerial spores and adhesion of pathogens to host structures.

Names & Taxonomyi

Protein namesi
Recommended name:
Hydrophobin-1
Alternative name(s):
Hydrophobin I
Short name:
HFBI
Gene namesi
Name:hfb1
OrganismiHypocrea jecorina (Trichoderma reesei)
Taxonomic identifieri51453 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesHypocreomycetidaeHypocrealesHypocreaceaeTrichoderma

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell wall, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 16Sequence analysisAdd BLAST16
PropeptideiPRO_000001351917 – 226
ChainiPRO_000001352023 – 97Hydrophobin-1Add BLAST75

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi30 ↔ 791 Publication
Disulfide bondi40 ↔ 701 Publication
Disulfide bondi41 ↔ 531 Publication
Disulfide bondi80 ↔ 911 Publication

Post-translational modificationi

Four disulfide bonds may be present.

Keywords - PTMi

Disulfide bond

Interactioni

Subunit structurei

Homodimer.Curated

Structurei

Secondary structure

197
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi26 – 30Combined sources5
Beta strandi37 – 45Combined sources9
Turni46 – 48Combined sources3
Beta strandi49 – 54Combined sources6
Helixi63 – 71Combined sources9
Turni72 – 74Combined sources3
Beta strandi76 – 81Combined sources6
Beta strandi86 – 90Combined sources5

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2FZ6X-ray2.10A/B/C/D23-97[»]
2GVMX-ray2.30A/B/C/D23-97[»]
ProteinModelPortaliP52754.
SMRiP52754.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP52754.

Family & Domainsi

Sequence similaritiesi

Belongs to the cerato-ulmin hydrophobin family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410J6WN. Eukaryota.
ENOG410ZA1T. LUCA.
OMAiKRICAES.

Family and domain databases

Gene3Di3.20.120.10. 1 hit.
InterProiIPR010636. Cerato-ulmin_hydrophobin.
[Graphical view]
PfamiPF06766. Hydrophobin_2. 1 hit.
[Graphical view]
SUPFAMiSSF101751. SSF101751. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P52754-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKFFAIAALF AAAAVAQPLE DRSNGNGNVC PPGLFSNPQC CATQVLGLIG
60 70 80 90
LDCKVPSQNV YDGTDFRNVC AKTGAQPLCC VAPVAGQALL CQTAVGA
Length:97
Mass (Da):9,874
Last modified:October 1, 1996 - v1
Checksum:iF30907B331EC3175
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z68124 Genomic DNA. Translation: CAA92208.1.
PIRiS62621.
S62625.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z68124 Genomic DNA. Translation: CAA92208.1.
PIRiS62621.
S62625.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2FZ6X-ray2.10A/B/C/D23-97[»]
2GVMX-ray2.30A/B/C/D23-97[»]
ProteinModelPortaliP52754.
SMRiP52754.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG410J6WN. Eukaryota.
ENOG410ZA1T. LUCA.
OMAiKRICAES.

Miscellaneous databases

EvolutionaryTraceiP52754.

Family and domain databases

Gene3Di3.20.120.10. 1 hit.
InterProiIPR010636. Cerato-ulmin_hydrophobin.
[Graphical view]
PfamiPF06766. Hydrophobin_2. 1 hit.
[Graphical view]
SUPFAMiSSF101751. SSF101751. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiHYP1_HYPJE
AccessioniPrimary (citable) accession number: P52754
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: November 2, 2016
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.