Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Zinc finger protein 135

Gene

ZNF135

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

Plays a role in the regulation of cell morphology and cytoskeletal organization. May be involved in transcriptional regulation.1 Publication

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri214 – 23623C2H2-type 1PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri242 – 26423C2H2-type 2PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri270 – 29223C2H2-type 3PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri298 – 32023C2H2-type 4PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri326 – 34823C2H2-type 5PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri354 – 37623C2H2-type 6PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri382 – 40423C2H2-type 7PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri410 – 43223C2H2-type 8PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri438 – 46023C2H2-type 9PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri466 – 48823C2H2-type 10PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri494 – 51623C2H2-type 11PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri522 – 54423C2H2-type 12PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri550 – 57223C2H2-type 13PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri578 – 60023C2H2-type 14PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri606 – 62823C2H2-type 15PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri634 – 65623C2H2-type 16PROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

  • DNA binding Source: UniProtKB-KW
  • metal ion binding Source: UniProtKB-KW
  • transcription factor activity, sequence-specific DNA binding Source: UniProtKB

GO - Biological processi

  • cytoskeleton organization Source: UniProtKB
  • regulation of cell morphogenesis Source: UniProtKB
  • regulation of transcription, DNA-templated Source: UniProtKB
  • transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Enzyme and pathway databases

ReactomeiR-HSA-212436. Generic Transcription Pathway.

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger protein 135
Alternative name(s):
Zinc finger protein 61
Zinc finger protein 78-like 1
Gene namesi
Name:ZNF135
Synonyms:ZNF61, ZNF78L1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

HGNCiHGNC:12919. ZNF135.

Subcellular locationi

GO - Cellular componenti

  • nucleus Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA37507.

Polymorphism and mutation databases

BioMutaiZNF135.
DMDMi296453071.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 658658Zinc finger protein 135PRO_0000047419Add
BLAST

Proteomic databases

EPDiP52742.
PaxDbiP52742.
PRIDEiP52742.

Expressioni

Gene expression databases

BgeeiP52742.
CleanExiHS_ZNF135.
ExpressionAtlasiP52742. baseline and differential.
GenevisibleiP52742. HS.

Organism-specific databases

HPAiHPA006961.

Interactioni

Protein-protein interaction databases

BioGridi113489. 6 interactions.
IntActiP52742. 7 interactions.
MINTiMINT-8247363.
STRINGi9606.ENSP00000441410.

Structurei

3D structure databases

ProteinModelPortaliP52742.
SMRiP52742. Positions 166-658.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini14 – 8572KRABPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 16 C2H2-type zinc fingers.PROSITE-ProRule annotation
Contains 1 KRAB domain.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri214 – 23623C2H2-type 1PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri242 – 26423C2H2-type 2PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri270 – 29223C2H2-type 3PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri298 – 32023C2H2-type 4PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri326 – 34823C2H2-type 5PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri354 – 37623C2H2-type 6PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri382 – 40423C2H2-type 7PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri410 – 43223C2H2-type 8PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri438 – 46023C2H2-type 9PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri466 – 48823C2H2-type 10PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri494 – 51623C2H2-type 11PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri522 – 54423C2H2-type 12PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri550 – 57223C2H2-type 13PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri578 – 60023C2H2-type 14PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri606 – 62823C2H2-type 15PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri634 – 65623C2H2-type 16PROSITE-ProRule annotationAdd
BLAST

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00840000129692.
HOGENOMiHOG000234617.
HOVERGENiHBG018163.
InParanoidiP52742.
OMAiECHECLK.
OrthoDBiEOG7KSX7Q.
PhylomeDBiP52742.
TreeFamiTF350822.

Family and domain databases

Gene3Di3.30.160.60. 16 hits.
InterProiIPR001909. KRAB.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF01352. KRAB. 1 hit.
PF00096. zf-C2H2. 9 hits.
PF13912. zf-C2H2_6. 3 hits.
[Graphical view]
SMARTiSM00349. KRAB. 1 hit.
SM00355. ZnF_C2H2. 16 hits.
[Graphical view]
SUPFAMiSSF109640. SSF109640. 1 hit.
PROSITEiPS50805. KRAB. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 16 hits.
PS50157. ZINC_FINGER_C2H2_2. 16 hits.
[Graphical view]

Sequences (4)i

Sequence statusi: Complete.

This entry describes 4 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: P52742-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MTPGVRVSTD PEQVTFEDVV VGFSQEEWGQ LKPAQRTLYR DVMLDTFRLL
60 70 80 90 100
VSVGHWLPKP NVISLLEQEA ELWAVESRLP QGVYPDLETR PKVKLSVLKQ
110 120 130 140 150
GISEEISNSV ILVERFLWDG LWYCRGEDTE GHWEWSCESL ESLAVPVAFT
160 170 180 190 200
PVKTPVLEQW QRNGFGENIS LNPDLPHQPM TPERQSPHTW GTRGKREKPD
210 220 230 240 250
LNVLQKTCVK EKPYKCQECG KAFSHSSALI EHHRTHTGER PYECHECLKG
260 270 280 290 300
FRNSSALTKH QRIHTGEKPY KCTQCGRTFN QIAPLIQHQR THTGEKPYEC
310 320 330 340 350
SECGKSFSFR SSFSQHERTH TGEKPYECSE CGKAFRQSIH LTQHLRIHTG
360 370 380 390 400
EKPYQCGECG KAFSHSSSLT KHQRIHTGEK PYECHECGKA FTQITPLIQH
410 420 430 440 450
QRTHTGEKPY ECGECGKAFS QSTLLTEHRR IHTGEKPYGC NECGKTFSHS
460 470 480 490 500
SSLSQHERTH TGEKPYECSQ CGKAFRQSTH LTQHQRIHTG EKPYECNDCG
510 520 530 540 550
KAFSHSSSLT KHQRIHTGEK PYECNQCGRA FSQLAPLIQH QRIHTGEKPY
560 570 580 590 600
ECNQCGRAFS QSSLLIEHQR IHTKEKPYGC NECGKSFSHS SSLSQHERTH
610 620 630 640 650
TGEKPYECHD CGKSFRQSTH LTQHRRIHTG EKPYACRDCG KAFTHSSSLT

KHQRTHTG
Length:658
Mass (Da):75,261
Last modified:May 18, 2010 - v3
Checksum:iED6A4FB042CB3CE5
GO
Isoform 2 (identifier: P52742-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-11: MTPGVRVSTDP → MELGSRRRSVGCRCRGLCLAVRR
     359-638: Missing.

Note: No experimental confirmation available.
Show »
Length:390
Mass (Da):44,822
Checksum:iCD54463064CF737B
GO
Isoform 3 (identifier: P52742-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     85-85: P → PEIKGHFQFLLLS

Note: No experimental confirmation available. May be due to competing acceptor splice site.
Show »
Length:670
Mass (Da):76,675
Checksum:iE070433AD8D6C9A5
GO
Isoform 4 (identifier: P52742-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-11: MTPGVRVSTDP → MELGSRRRSVGCRCRGLCLAVRR
     85-85: P → PEIKGHFQFLLLS

Note: Gene prediction based on EST data.
Show »
Length:682
Mass (Da):78,151
Checksum:iC4D2B1A44B70570B
GO

Sequence cautioni

The sequence AAC50254.1 differs from that shown. Reason: Frameshift at positions 207, 558 and 563. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti166 – 1661G → R in AAC50254 (PubMed:7557990).Curated
Sequence conflicti247 – 2471C → F in BAG58141 (PubMed:14702039).Curated
Sequence conflicti308 – 3081S → C in BAG58141 (PubMed:14702039).Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti22 – 221G → D.2 Publications
Corresponds to variant rs1469087 [ dbSNP | Ensembl ].
VAR_052774
Natural varianti507 – 5071S → L.
Corresponds to variant rs2228277 [ dbSNP | Ensembl ].
VAR_052775
Natural varianti517 – 5171T → A.
Corresponds to variant rs2228278 [ dbSNP | Ensembl ].
VAR_052776
Natural varianti579 – 5791G → R.
Corresponds to variant rs2228279 [ dbSNP | Ensembl ].
VAR_052777
Natural varianti592 – 5921S → L.
Corresponds to variant rs2228275 [ dbSNP | Ensembl ].
VAR_052778

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 1111MTPGVRVSTDP → MELGSRRRSVGCRCRGLCLA VRR in isoform 2 and isoform 4. 1 PublicationVSP_046073Add
BLAST
Alternative sequencei85 – 851P → PEIKGHFQFLLLS in isoform 3 and isoform 4. 1 PublicationVSP_046706
Alternative sequencei359 – 638280Missing in isoform 2. 1 PublicationVSP_046074Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK098011 mRNA. Translation: BAC05214.1.
AK295110 mRNA. Translation: BAG58141.1.
AC008751 Genomic DNA. No translation available.
CH471135 Genomic DNA. Translation: EAW72553.1.
BC046434 mRNA. Translation: AAH46434.1.
U09413 mRNA. Translation: AAC50254.1. Frameshift.
CCDSiCCDS12970.2. [P52742-3]
CCDS54329.1. [P52742-4]
CCDS54330.1. [P52742-2]
CCDS74471.1. [P52742-1]
PIRiI38600.
RefSeqiNP_001158001.1. NM_001164529.1.
NP_001158002.1. NM_001164530.1. [P52742-2]
NP_001276330.1. NM_001289401.1. [P52742-1]
NP_001276331.1. NM_001289402.1.
NP_003427.3. NM_003436.3. [P52742-3]
NP_009065.1. NM_007134.1. [P52742-4]
XP_006723425.1. XM_006723362.2. [P52742-3]
XP_006723426.1. XM_006723363.2. [P52742-3]
UniGeneiHs.85863.

Genome annotation databases

EnsembliENST00000313434; ENSP00000321406; ENSG00000176293. [P52742-1]
ENST00000359978; ENSP00000369437; ENSG00000176293. [P52742-2]
ENST00000401053; ENSP00000441410; ENSG00000176293. [P52742-4]
ENST00000511556; ENSP00000422074; ENSG00000176293. [P52742-3]
GeneIDi7694.
UCSCiuc002qrd.3. human. [P52742-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK098011 mRNA. Translation: BAC05214.1.
AK295110 mRNA. Translation: BAG58141.1.
AC008751 Genomic DNA. No translation available.
CH471135 Genomic DNA. Translation: EAW72553.1.
BC046434 mRNA. Translation: AAH46434.1.
U09413 mRNA. Translation: AAC50254.1. Frameshift.
CCDSiCCDS12970.2. [P52742-3]
CCDS54329.1. [P52742-4]
CCDS54330.1. [P52742-2]
CCDS74471.1. [P52742-1]
PIRiI38600.
RefSeqiNP_001158001.1. NM_001164529.1.
NP_001158002.1. NM_001164530.1. [P52742-2]
NP_001276330.1. NM_001289401.1. [P52742-1]
NP_001276331.1. NM_001289402.1.
NP_003427.3. NM_003436.3. [P52742-3]
NP_009065.1. NM_007134.1. [P52742-4]
XP_006723425.1. XM_006723362.2. [P52742-3]
XP_006723426.1. XM_006723363.2. [P52742-3]
UniGeneiHs.85863.

3D structure databases

ProteinModelPortaliP52742.
SMRiP52742. Positions 166-658.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi113489. 6 interactions.
IntActiP52742. 7 interactions.
MINTiMINT-8247363.
STRINGi9606.ENSP00000441410.

Polymorphism and mutation databases

BioMutaiZNF135.
DMDMi296453071.

Proteomic databases

EPDiP52742.
PaxDbiP52742.
PRIDEiP52742.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000313434; ENSP00000321406; ENSG00000176293. [P52742-1]
ENST00000359978; ENSP00000369437; ENSG00000176293. [P52742-2]
ENST00000401053; ENSP00000441410; ENSG00000176293. [P52742-4]
ENST00000511556; ENSP00000422074; ENSG00000176293. [P52742-3]
GeneIDi7694.
UCSCiuc002qrd.3. human. [P52742-1]

Organism-specific databases

CTDi7694.
GeneCardsiZNF135.
HGNCiHGNC:12919. ZNF135.
HPAiHPA006961.
MIMi604077. gene.
neXtProtiNX_P52742.
PharmGKBiPA37507.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00840000129692.
HOGENOMiHOG000234617.
HOVERGENiHBG018163.
InParanoidiP52742.
OMAiECHECLK.
OrthoDBiEOG7KSX7Q.
PhylomeDBiP52742.
TreeFamiTF350822.

Enzyme and pathway databases

ReactomeiR-HSA-212436. Generic Transcription Pathway.

Miscellaneous databases

GenomeRNAii7694.
NextBioi29824.
PROiP52742.
SOURCEiSearch...

Gene expression databases

BgeeiP52742.
CleanExiHS_ZNF135.
ExpressionAtlasiP52742. baseline and differential.
GenevisibleiP52742. HS.

Family and domain databases

Gene3Di3.30.160.60. 16 hits.
InterProiIPR001909. KRAB.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF01352. KRAB. 1 hit.
PF00096. zf-C2H2. 9 hits.
PF13912. zf-C2H2_6. 3 hits.
[Graphical view]
SMARTiSM00349. KRAB. 1 hit.
SM00355. ZnF_C2H2. 16 hits.
[Graphical view]
SUPFAMiSSF109640. SSF109640. 1 hit.
PROSITEiPS50805. KRAB. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 16 hits.
PS50157. ZINC_FINGER_C2H2_2. 16 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 3), VARIANT ASP-22.
    Tissue: Brain and Thymus.
  2. "The DNA sequence and biology of human chromosome 19."
    Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S., Carrano A.V.
    , Caoile C., Chan Y.M., Christensen M., Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E., Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M., Rubin E.M., Lucas S.M.
    Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANT ASP-22.
    Tissue: Testis.
  5. "Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders."
    Tommerup N., Vissing H.
    Genomics 27:259-264(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 166-658 (ISOFORM 1).
    Tissue: Insulinoma.
  6. "Identification and characterization of a set of conserved and new regulators of cytoskeletal organisation, cell morphology and migration."
    Bai S.W., Herrera-Abreu M.T., Rohn J.L., Racine V., Tajadura V., Suryavanshi N., Bechtel S., Wiemann S., Baum B., Ridley A.J.
    BMC Biol. 9:54-54(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.

Entry informationi

Entry nameiZN135_HUMAN
AccessioniPrimary (citable) accession number: P52742
Secondary accession number(s): B4DHH9
, E9PEV2, F5GYY9, I3L0B3, Q5U5L3, Q8N1I7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: May 18, 2010
Last modified: May 11, 2016
This is version 140 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.