Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P52711

- CBP23_HORVU

UniProt

P52711 - CBP23_HORVU

Protein

Serine carboxypeptidase II-3

Gene

CXP;2-3

Organism
Hordeum vulgare (Barley)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 70 (01 Oct 2014)
      Sequence version 1 (01 Oct 1996)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    Preferential release of a C-terminal arginine or lysine residue.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei236 – 2361By similarity
    Active sitei427 – 4271By similarity
    Active sitei484 – 4841By similarity

    GO - Molecular functioni

    1. serine-type carboxypeptidase activity Source: InterPro

    Keywords - Molecular functioni

    Carboxypeptidase, Hydrolase, Protease

    Protein family/group databases

    MEROPSiS10.005.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Serine carboxypeptidase II-3 (EC:3.4.16.6)
    Alternative name(s):
    CP-MII.3
    Cleaved into the following 2 chains:
    Gene namesi
    Name:CXP;2-3
    OrganismiHordeum vulgare (Barley)
    Taxonomic identifieri4513 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladePooideaeTriticeaeHordeum

    Organism-specific databases

    GrameneiP52711.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2020Sequence AnalysisAdd
    BLAST
    Propeptidei21 – 7757Sequence AnalysisPRO_0000004320Add
    BLAST
    Chaini78 – 341264Serine carboxypeptidase II-3 chain APRO_0000004321Add
    BLAST
    Propeptidei342 – 35211Linker peptideBy similarityPRO_0000004322Add
    BLAST
    Chaini353 – 516164Serine carboxypeptidase II-3 chain BPRO_0000004323Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Disulfide bondi143 ↔ 391Interchain (between A and B chains)By similarity
    Glycosylationi194 – 1941N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi205 – 2051N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi300 ↔ 315By similarity
    Glycosylationi301 – 3011N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi339 ↔ 359Interchain (between A and B chains)By similarity
    Glycosylationi380 – 3801N-linked (GlcNAc...)Sequence Analysis

    Post-translational modificationi

    The linker peptide is endoproteolytically excised during enzyme maturation.By similarity

    Keywords - PTMi

    Disulfide bond, Glycoprotein, Zymogen

    Expressioni

    Developmental stagei

    Expressed in the germinating embryo. Also found in the roots and shoots of the growing seedling.

    Gene expression databases

    GenevestigatoriP52711.

    Interactioni

    Subunit structurei

    Carboxypeptidase II is a dimer, where each monomer is composed of two chains linked by a disulfide bond.By similarity

    Structurei

    3D structure databases

    ProteinModelPortaliP52711.
    SMRiP52711. Positions 82-340.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the peptidase S10 family.Curated

    Keywords - Domaini

    Signal

    Family and domain databases

    Gene3Di3.40.50.1820. 1 hit.
    InterProiIPR029058. AB_hydrolase.
    IPR001563. Peptidase_S10.
    IPR018202. Peptidase_S10_AS.
    [Graphical view]
    PANTHERiPTHR11802. PTHR11802. 1 hit.
    PfamiPF00450. Peptidase_S10. 1 hit.
    [Graphical view]
    PRINTSiPR00724. CRBOXYPTASEC.
    SUPFAMiSSF53474. SSF53474. 1 hit.
    PROSITEiPS00560. CARBOXYPEPT_SER_HIS. 1 hit.
    PS00131. CARBOXYPEPT_SER_SER. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P52711-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKCTVVALVL LVAVQCLVLG AGPAAAAKAR RTRQGDYLNR LRGSPSSRAS    50
    WESLAAVEEQ TTTKAAGRPA PVAAAVEAGR KEADRVEALP GHPRGVDFAQ 100
    YAGYVTVDAA AGRALFYYLA EAVGGNGDKT KPLLLWLNGG PGCSSLGYGA 150
    MEELGPFRVM SDGKTLYSNP YSWNHAANVL FLESPAGVGY SYSNTTADYG 200
    RSGDNGTAED AYQFLDNWLE RFPEYKGREF YITGESYAGH YVPQLAHAIL 250
    RHASPDINLK GIMIGNAVIN DWTDSKGMYD FFWTHALISD ETADGISKNC 300
    NFTAYGAGVA SNALCDAASD EVGESLADID IYNIYAPNCQ SEKLVTPPIA 350
    PSIDNFDPCT DYYVEAYLNR PDVQKALHAN VTRLDHPWSA CSDVLTRWVD 400
    SAKTVLPIIQ ELMKNSIRVW VYSGDTDGRV PVTSSRLSVN QLQLPVAAKW 450
    RPWFSSTKGA GEVGGYIVQY KGDLSLVTVR GAGHEVPSYQ PRRALVLVQN 500
    FLAGKALPDC KECEQD 516
    Length:516
    Mass (Da):55,914
    Last modified:October 1, 1996 - v1
    Checksum:iD41AA1C56CF8D355
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X78877 mRNA. Translation: CAA55478.1.
    PIRiS44191.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X78877 mRNA. Translation: CAA55478.1 .
    PIRi S44191.

    3D structure databases

    ProteinModelPortali P52711.
    SMRi P52711. Positions 82-340.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    MEROPSi S10.005.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    Gramenei P52711.

    Gene expression databases

    Genevestigatori P52711.

    Family and domain databases

    Gene3Di 3.40.50.1820. 1 hit.
    InterProi IPR029058. AB_hydrolase.
    IPR001563. Peptidase_S10.
    IPR018202. Peptidase_S10_AS.
    [Graphical view ]
    PANTHERi PTHR11802. PTHR11802. 1 hit.
    Pfami PF00450. Peptidase_S10. 1 hit.
    [Graphical view ]
    PRINTSi PR00724. CRBOXYPTASEC.
    SUPFAMi SSF53474. SSF53474. 1 hit.
    PROSITEi PS00560. CARBOXYPEPT_SER_HIS. 1 hit.
    PS00131. CARBOXYPEPT_SER_SER. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The expression of serine carboxypeptidases during maturation and germination of the barley grain."
      Dal Degan F., Rocher A., Cameron-Mills V., von Wettstein D.
      Proc. Natl. Acad. Sci. U.S.A. 91:8209-8213(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Strain: cv. Alexis.
      Tissue: Grain.

    Entry informationi

    Entry nameiCBP23_HORVU
    AccessioniPrimary (citable) accession number: P52711
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 1, 1996
    Last sequence update: October 1, 1996
    Last modified: October 1, 2014
    This is version 70 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Documents

    1. Peptidase families
      Classification of peptidase families and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3