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P52711

- CBP23_HORVU

UniProt

P52711 - CBP23_HORVU

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Protein

Serine carboxypeptidase II-3

Gene

CXP;2-3

Organism
Hordeum vulgare (Barley)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Preferential release of a C-terminal arginine or lysine residue.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei236 – 2361By similarity
Active sitei427 – 4271By similarity
Active sitei484 – 4841By similarity

GO - Molecular functioni

  1. serine-type carboxypeptidase activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Carboxypeptidase, Hydrolase, Protease

Protein family/group databases

MEROPSiS10.005.

Names & Taxonomyi

Protein namesi
Recommended name:
Serine carboxypeptidase II-3 (EC:3.4.16.6)
Alternative name(s):
CP-MII.3
Cleaved into the following 2 chains:
Gene namesi
Name:CXP;2-3
OrganismiHordeum vulgare (Barley)
Taxonomic identifieri4513 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladePooideaeTriticeaeHordeum

Organism-specific databases

GrameneiP52711.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2020Sequence AnalysisAdd
BLAST
Propeptidei21 – 7757Sequence AnalysisPRO_0000004320Add
BLAST
Chaini78 – 341264Serine carboxypeptidase II-3 chain APRO_0000004321Add
BLAST
Propeptidei342 – 35211Linker peptideBy similarityPRO_0000004322Add
BLAST
Chaini353 – 516164Serine carboxypeptidase II-3 chain BPRO_0000004323Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi143 ↔ 391Interchain (between A and B chains)By similarity
Glycosylationi194 – 1941N-linked (GlcNAc...)Sequence Analysis
Glycosylationi205 – 2051N-linked (GlcNAc...)Sequence Analysis
Disulfide bondi300 ↔ 315By similarity
Glycosylationi301 – 3011N-linked (GlcNAc...)Sequence Analysis
Disulfide bondi339 ↔ 359Interchain (between A and B chains)By similarity
Glycosylationi380 – 3801N-linked (GlcNAc...)Sequence Analysis

Post-translational modificationi

The linker peptide is endoproteolytically excised during enzyme maturation.By similarity

Keywords - PTMi

Disulfide bond, Glycoprotein, Zymogen

Expressioni

Developmental stagei

Expressed in the germinating embryo. Also found in the roots and shoots of the growing seedling.

Gene expression databases

GenevestigatoriP52711.

Interactioni

Subunit structurei

Carboxypeptidase II is a dimer, where each monomer is composed of two chains linked by a disulfide bond.By similarity

Structurei

3D structure databases

ProteinModelPortaliP52711.
SMRiP52711. Positions 82-340.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase S10 family.Curated

Keywords - Domaini

Signal

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR001563. Peptidase_S10.
IPR018202. Peptidase_S10_AS.
[Graphical view]
PANTHERiPTHR11802. PTHR11802. 1 hit.
PfamiPF00450. Peptidase_S10. 1 hit.
[Graphical view]
PRINTSiPR00724. CRBOXYPTASEC.
SUPFAMiSSF53474. SSF53474. 1 hit.
PROSITEiPS00560. CARBOXYPEPT_SER_HIS. 1 hit.
PS00131. CARBOXYPEPT_SER_SER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P52711-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKCTVVALVL LVAVQCLVLG AGPAAAAKAR RTRQGDYLNR LRGSPSSRAS
60 70 80 90 100
WESLAAVEEQ TTTKAAGRPA PVAAAVEAGR KEADRVEALP GHPRGVDFAQ
110 120 130 140 150
YAGYVTVDAA AGRALFYYLA EAVGGNGDKT KPLLLWLNGG PGCSSLGYGA
160 170 180 190 200
MEELGPFRVM SDGKTLYSNP YSWNHAANVL FLESPAGVGY SYSNTTADYG
210 220 230 240 250
RSGDNGTAED AYQFLDNWLE RFPEYKGREF YITGESYAGH YVPQLAHAIL
260 270 280 290 300
RHASPDINLK GIMIGNAVIN DWTDSKGMYD FFWTHALISD ETADGISKNC
310 320 330 340 350
NFTAYGAGVA SNALCDAASD EVGESLADID IYNIYAPNCQ SEKLVTPPIA
360 370 380 390 400
PSIDNFDPCT DYYVEAYLNR PDVQKALHAN VTRLDHPWSA CSDVLTRWVD
410 420 430 440 450
SAKTVLPIIQ ELMKNSIRVW VYSGDTDGRV PVTSSRLSVN QLQLPVAAKW
460 470 480 490 500
RPWFSSTKGA GEVGGYIVQY KGDLSLVTVR GAGHEVPSYQ PRRALVLVQN
510
FLAGKALPDC KECEQD
Length:516
Mass (Da):55,914
Last modified:October 1, 1996 - v1
Checksum:iD41AA1C56CF8D355
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X78877 mRNA. Translation: CAA55478.1.
PIRiS44191.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X78877 mRNA. Translation: CAA55478.1 .
PIRi S44191.

3D structure databases

ProteinModelPortali P52711.
SMRi P52711. Positions 82-340.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

MEROPSi S10.005.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

Gramenei P52711.

Gene expression databases

Genevestigatori P52711.

Family and domain databases

Gene3Di 3.40.50.1820. 1 hit.
InterProi IPR029058. AB_hydrolase.
IPR001563. Peptidase_S10.
IPR018202. Peptidase_S10_AS.
[Graphical view ]
PANTHERi PTHR11802. PTHR11802. 1 hit.
Pfami PF00450. Peptidase_S10. 1 hit.
[Graphical view ]
PRINTSi PR00724. CRBOXYPTASEC.
SUPFAMi SSF53474. SSF53474. 1 hit.
PROSITEi PS00560. CARBOXYPEPT_SER_HIS. 1 hit.
PS00131. CARBOXYPEPT_SER_SER. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The expression of serine carboxypeptidases during maturation and germination of the barley grain."
    Dal Degan F., Rocher A., Cameron-Mills V., von Wettstein D.
    Proc. Natl. Acad. Sci. U.S.A. 91:8209-8213(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: cv. Alexis.
    Tissue: Grain.

Entry informationi

Entry nameiCBP23_HORVU
AccessioniPrimary (citable) accession number: P52711
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: October 1, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. Peptidase families
    Classification of peptidase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3