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Protein

HTH-type transcriptional regulator PhcA

Gene

phcA

Organism
Ralstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Protein predictedi

Functioni

Regulates the transcription of one or more of the genes involved in virulence.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi21 – 40H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation, Virulence

Names & Taxonomyi

Protein namesi
Recommended name:
HTH-type transcriptional regulator PhcA
Alternative name(s):
Virulence genes transcriptional regulator PhcA
Gene namesi
Name:phcA
Ordered Locus Names:RSc2748
ORF Names:RS00106
OrganismiRalstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum)
Taxonomic identifieri267608 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeRalstonia
Proteomesi
  • UP000001436 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

  • protein-DNA complex Source: CollecTF

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001057441 – 347HTH-type transcriptional regulator PhcAAdd BLAST347

Structurei

3D structure databases

ProteinModelPortaliP52698.
SMRiP52698.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 61HTH lysR-typePROSITE-ProRule annotationAdd BLAST61

Phylogenomic databases

eggNOGiENOG4105G2Y. Bacteria.
ENOG410XRYC. LUCA.
HOGENOMiHOG000061926.
KOiK19624.
OMAiRRFAAWE.
OrthoDBiPOG091H05H6.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiView protein in InterPro
IPR005119. LysR_subst-bd.
IPR000847. Tscrpt_reg_HTH_LysR.
IPR036388. WH-like_DNA-bd_sf.
IPR036390. WH_DNA-bd_sf.
PfamiView protein in Pfam
PF00126. HTH_1. 1 hit.
PF03466. LysR_substrate. 1 hit.
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiView protein in PROSITE
PS50931. HTH_LYSR. 1 hit.

Sequencei

Sequence statusi: Complete.

P52698-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVNVDTKLLV IFVELLSKRN ATYVAEKMHM TAPAVSHSLG RLREIFDDPL
60 70 80 90 100
FIRVPHGLTP TPKALELGPK VREMLDLWAA INEGDIATFD PLEAAGTFNI
110 120 130 140 150
SFAGTLGDAL FDRFLLRVKR LAPGLQVRLT ESSSWEADVA AMRSNELDLA
160 170 180 190 200
FSPFPTRHPE IVEEVVTSFN MWVCARKDHP VLKDHCSLDQ YLECEHIFIA
210 220 230 240 250
QGNPGTRAAP SLIPLDYALQ QRGLKRHSTM TVHAWRTQAE VAAQTDMIFT
260 270 280 290 300
VNSLMKDLVC ETYNLNAFPL PSELETVLGL NMLWHRSRNT HPMLVWARNL
310 320 330 340
FKQVVAEYTG KASIAPMHPP MLTDDSGKSG KTGKGDAEKE DESRLSV
Length:347
Mass (Da):38,791
Last modified:January 23, 2002 - v2
Checksum:i00DD51779F21782B
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural varianti92L → A in strain: AW1 and ACH0158. 1
Natural varianti100I → V in strain: AW1 and ACH0158. 1
Natural varianti185H → G in strain: ACH0158. 1
Natural varianti185H → R in strain: AW1. 1
Natural varianti206T → S in strain: AW1 and ACH0158. 1
Natural varianti247M → L in strain: AW1 and ACH0158. 1
Natural varianti262T → A in strain: AW1 and ACH0158. 1
Natural varianti264N → S in strain: ACH0158. 1
Natural varianti314I → N in strain: AW1 and ACH0158. 1
Natural varianti329S → A in strain: AW1 and ACH0158. 1
Natural varianti347V → A in strain: AW1 and ACH0158. 1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L19269 Unassigned DNA. Translation: AAC36989.1.
AF184046 Genomic DNA. Translation: AAD56543.1.
AF239238 Genomic DNA. Translation: AAK15051.1.
AL646052 Genomic DNA. Translation: CAD16455.1.
PIRiA48655.
RefSeqiWP_011002655.1. NC_003295.1.

Genome annotation databases

EnsemblBacteriaiCAD16455; CAD16455; RSc2748.
GeneIDi1221595.
KEGGirso:RSc2748.
PATRICifig|267608.8.peg.2795.

Similar proteinsi

Entry informationi

Entry nameiPHCA_RALSO
AccessioniPrimary (citable) accession number: P52698
Secondary accession number(s): Q9AIT9, Q9RBU2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: January 23, 2002
Last modified: October 25, 2017
This is version 105 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome