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Protein

Uncharacterized HTH-type transcriptional regulator YbhD

Gene

ybhD

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi20 – 4021H-T-H motifPROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciEcoCyc:G6398-MONOMER.
ECOL316407:JW5896-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized HTH-type transcriptional regulator YbhD
Gene namesi
Name:ybhD
Ordered Locus Names:b0768, JW5896
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13230. ybhD.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 317317Uncharacterized HTH-type transcriptional regulator YbhDPRO_0000105780Add
BLAST

Proteomic databases

PaxDbiP52696.
PRIDEiP52696.

Interactioni

Protein-protein interaction databases

BioGridi4261144. 2 interactions.
STRINGi511145.b0768.

Structurei

3D structure databases

ProteinModelPortaliP52696.
SMRiP52696. Positions 4-263.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 6060HTH lysR-typePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 HTH lysR-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4105F04. Bacteria.
ENOG410XRIM. LUCA.
HOGENOMiHOG000233514.
InParanoidiP52696.
OMAiESFHRAA.
OrthoDBiEOG686NGM.
PhylomeDBiP52696.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR005119. LysR_subst-bd.
IPR000847. Tscrpt_reg_HTH_LysR.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00126. HTH_1. 1 hit.
PF03466. LysR_substrate. 1 hit.
[Graphical view]
PRINTSiPR00039. HTHLYSR.
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiPS50931. HTH_LYSR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P52696-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKHELSSMKA FVILAESSSF NNAAKLLNIT QPALTRRIKK MEEDLHVQLF
60 70 80 90 100
ERTTRKVTLT KAGKRLLPEA RELIKKFDET LFNIRDMNAY HRGMVTLACI
110 120 130 140 150
PTAVFYFLPL AIGKFNELYP NIKVRILEQG TNNCMESVLC NESDFGINMN
160 170 180 190 200
NVTNSSIDFT PLVNEPFVLA CRRDHPLAKK QLVEWQELVG YKMIGVRSSS
210 220 230 240 250
GNRLLIEQQL ADKPWKLDWF YEVRHLSTSL GLVEAGLGIS ALPGLAMPHA
260 270 280 290 300
PYSSIIGIPL VEPVIRRTLG IIRRKDAVLS PAAERFFALL INLWTDDKDN
310
LWTNIVERQR HALQEIG
Length:317
Mass (Da):36,058
Last modified:April 27, 2001 - v3
Checksum:i8B02C4808B4665D2
GO

Sequence cautioni

The sequence BAA35432.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC73855.2.
AP009048 Genomic DNA. Translation: BAA35432.1. Different initiation.
U27192 Genomic DNA. No translation available.
PIRiH64812.
RefSeqiNP_415289.4. NC_000913.3.
WP_001350493.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73855; AAC73855; b0768.
BAA35432; BAA35432; BAA35432.
GeneIDi944869.
KEGGiecj:JW5896.
eco:b0768.
PATRICi32116737. VBIEscCol129921_0794.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC73855.2.
AP009048 Genomic DNA. Translation: BAA35432.1. Different initiation.
U27192 Genomic DNA. No translation available.
PIRiH64812.
RefSeqiNP_415289.4. NC_000913.3.
WP_001350493.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP52696.
SMRiP52696. Positions 4-263.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261144. 2 interactions.
STRINGi511145.b0768.

Proteomic databases

PaxDbiP52696.
PRIDEiP52696.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73855; AAC73855; b0768.
BAA35432; BAA35432; BAA35432.
GeneIDi944869.
KEGGiecj:JW5896.
eco:b0768.
PATRICi32116737. VBIEscCol129921_0794.

Organism-specific databases

EchoBASEiEB3019.
EcoGeneiEG13230. ybhD.

Phylogenomic databases

eggNOGiENOG4105F04. Bacteria.
ENOG410XRIM. LUCA.
HOGENOMiHOG000233514.
InParanoidiP52696.
OMAiESFHRAA.
OrthoDBiEOG686NGM.
PhylomeDBiP52696.

Enzyme and pathway databases

BioCyciEcoCyc:G6398-MONOMER.
ECOL316407:JW5896-MONOMER.

Miscellaneous databases

PROiP52696.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR005119. LysR_subst-bd.
IPR000847. Tscrpt_reg_HTH_LysR.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00126. HTH_1. 1 hit.
PF03466. LysR_substrate. 1 hit.
[Graphical view]
PRINTSiPR00039. HTHLYSR.
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiPS50931. HTH_LYSR. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  4. Shanmugam K.T.
    Submitted (MAY-1995) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 210-317.
    Strain: K12.
  5. Robison K.
    Unpublished observations (DEC-1995)
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiYBHD_ECOLI
AccessioniPrimary (citable) accession number: P52696
Secondary accession number(s): P75761
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: April 27, 2001
Last modified: July 6, 2016
This is version 112 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.