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Protein

HTH-type transcriptional regulator BlaA

Gene

blaA

Organism
Proteus vulgaris
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein predictedi

Functioni

Positive regulator of the expression of the gene (blaB) for beta-lactamase.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi22 – 41H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActivator, DNA-binding
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
HTH-type transcriptional regulator BlaA
Alternative name(s):
Beta-lactamase regulatory protein BlaA
Gene namesi
Name:blaA
Synonyms:cumR
OrganismiProteus vulgaris
Taxonomic identifieri585 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesMorganellaceaeProteus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001055951 – 292HTH-type transcriptional regulator BlaAAdd BLAST292

Structurei

3D structure databases

ProteinModelPortaliP52660.
SMRiP52660.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 62HTH lysR-typePROSITE-ProRule annotationAdd BLAST58

Family and domain databases

CDDicd08487. PBP2_BlaA. 1 hit.
Gene3Di1.10.10.10. 1 hit.
InterProiView protein in InterPro
IPR037422. BlaA_PBP2.
IPR005119. LysR_subst-bd.
IPR000847. Tscrpt_reg_HTH_LysR.
IPR036388. WH-like_DNA-bd_sf.
IPR036390. WH_DNA-bd_sf.
PfamiView protein in Pfam
PF00126. HTH_1. 1 hit.
PF03466. LysR_substrate. 1 hit.
PRINTSiPR00039. HTHLYSR.
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiView protein in PROSITE
PS50931. HTH_LYSR. 1 hit.

Sequencei

Sequence statusi: Complete.

P52660-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRTHLPLNAL RAFEASARHL NFTKAALELY VTQGAVSQQV RMLEERLGVI
60 70 80 90 100
LFKRLPRGLE MTDDAQILFS VLTTAFSDIE RVFKQFERGE YRDVVSIAAV
110 120 130 140 150
GTFAVGWLLP RLAEFRQLYP RIELNLRTNN NVVNLATEGL DFAIRFGEGL
160 170 180 190 200
WPLTHNKALF SAPLTVLCSS DTAKPLQHPT DLINETLYRS YREDEWLQWF
210 220 230 240 250
EKANMSPIKI TGSIFDPSRL MIESAIYEGG VALAPAKMFS REIENGQLVQ
260 270 280 290
PFKIEVELGK YWLTYLKSKP MTASMEIFQQ WLMNEALKEI SE
Length:292
Mass (Da):33,443
Last modified:October 1, 1996 - v1
Checksum:iD07D3D9F7D4F3207
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural varianti124L → V in strain: 5E78-1. 1
Natural varianti171D → G in strain: 5E78-1. 1
Natural varianti175P → R in strain: 5E78-1. 1
Natural varianti186T → N in strain: 5E78-1. 1
Natural varianti217P → S in strain: 5E78-1. 1
Natural varianti258L → M in strain: 5E78-1. 1
Natural varianti284N → S in strain: 5E78-1. 1
Natural varianti290I → C in strain: 5E78-1. 1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X80128 Genomic DNA. Translation: CAA56428.1.
D37831 Genomic DNA. Translation: BAA07083.1.
PIRiS51045.

Similar proteinsi

Entry informationi

Entry nameiBLAA_PROVU
AccessioniPrimary (citable) accession number: P52660
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: January 31, 2018
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program