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Protein

Phase 2 flagellin

Gene

fljB

Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.

Miscellaneous

Individual Salmonella serotypes usually alternate between the production of 2 antigenic forms of flagella, termed phase 1 and phase 2, each specified by separate structural genes.

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-GGA-433822. NFkB and MAPK activation mediated by TRAF6.
R-GGA-451534. TLR5 cascade.
R-GGA-977240. MyD88 cascade initiated on plasma membrane.
R-HSA-844623. The IPAF inflammasome.

Names & Taxonomyi

Protein namesi
Recommended name:
Phase 2 flagellin
Gene namesi
Name:fljB
Synonyms:H2
Ordered Locus Names:STM2771
OrganismiSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Taxonomic identifieri99287 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeSalmonella
Proteomesi
  • UP000001014 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Bacterial flagellum, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00001825802 – 506Phase 2 flagellinAdd BLAST505

Proteomic databases

PaxDbiP52616.
PRIDEiP52616.

Interactioni

Protein-protein interaction databases

STRINGi99287.STM2771.

Structurei

3D structure databases

ProteinModelPortaliP52616.
SMRiP52616.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the bacterial flagellin family.Curated

Phylogenomic databases

eggNOGiENOG4105I03. Bacteria.
COG1344. LUCA.
HOGENOMiHOG000255144.
KOiK02406.
OMAiFEHTINN.
PhylomeDBiP52616.

Family and domain databases

InterProiView protein in InterPro
IPR001492. Flagellin.
IPR001029. Flagellin_D0/D1.
IPR014981. Flagellin_D3.
PfamiView protein in Pfam
PF00700. Flagellin_C. 1 hit.
PF08884. Flagellin_D3. 1 hit.
PF00669. Flagellin_N. 1 hit.
PRINTSiPR00207. FLAGELLIN.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P52616-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQVINTNSL SLLTQNNLNK SQSALGTAIE RLSSGLRINS AKDDAAGQAI
60 70 80 90 100
ANRFTANIKG LTQASRNAND GISIAQTTEG ALNEINNNLQ RVRELAVQSA
110 120 130 140 150
NSTNSQSDLD SIQAEITQRL NEIDRVSGQT QFNGVKVLAQ DNTLTIQVGA
160 170 180 190 200
NDGETIDIDL KQINSQTLGL DSLNVQKAYD VKDTAVTTKA YANNGTTLDV
210 220 230 240 250
SGLDDAAIKA ATGGTNGTAS VTGGAVKFDA DNNKYFVTIG GFTGADAAKN
260 270 280 290 300
GDYEVNVATD GTVTLAAGAT KTTMPAGATT KTEVQELKDT PAVVSADAKN
310 320 330 340 350
ALIAGGVDAT DANGAELVKM SYTDKNGKTI EGGYALKAGD KYYAADYDEA
360 370 380 390 400
TGAIKAKTTS YTAADGTTKT AANQLGGVDG KTEVVTIDGK TYNASKAAGH
410 420 430 440 450
DFKAQPELAE AAAKTTENPL QKIDAALAQV DALRSDLGAV QNRFNSAITN
460 470 480 490 500
LGNTVNNLSE ARSRIEDSDY ATEVSNMSRA QILQQAGTSV LAQANQVPQN

VLSLLR
Length:506
Mass (Da):52,536
Last modified:January 23, 2007 - v2
Checksum:i3A4051A9AF7AF88B
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti38I → S in CAA24655 (PubMed:6271461).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U17177 Genomic DNA. Translation: AAC43354.1.
AE006468 Genomic DNA. Translation: AAL21657.1.
V01370 Genomic DNA. Translation: CAA24655.1.
D26168 Genomic DNA. Translation: BAA05156.1.
RefSeqiNP_461698.1. NC_003197.2.
WP_000079794.1. NC_003197.2.

Genome annotation databases

EnsemblBacteriaiAAL21657; AAL21657; STM2771.
GeneIDi1254294.
KEGGistm:STM2771.
PATRICifig|99287.12.peg.2923.

Similar proteinsi

Entry informationi

Entry nameiFLJB_SALTY
AccessioniPrimary (citable) accession number: P52616
Secondary accession number(s): P97159
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: January 23, 2007
Last modified: December 20, 2017
This is version 105 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families