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Protein

Flagellar hook-length control protein

Gene

fliK

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Controls the length of the flagellar hook.

GO - Biological processi

  • bacterial-type flagellum assembly Source: InterPro
  • bacterial-type flagellum-dependent cell motility Source: EcoCyc
Complete GO annotation...

Keywords - Biological processi

Bacterial flagellum biogenesis

Enzyme and pathway databases

BioCyciEcoCyc:G379-MONOMER.
ECOL316407:JW1927-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Flagellar hook-length control protein
Gene namesi
Name:fliK
Synonyms:flaE, flaR
Ordered Locus Names:b1943, JW1927
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG20268. fliK.

Subcellular locationi

GO - Cellular componenti

  • bacterial-type flagellum hook Source: EcoliWiki
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 375375Flagellar hook-length control proteinPRO_0000180908Add
BLAST

Proteomic databases

PaxDbiP52614.

Interactioni

Protein-protein interaction databases

BioGridi4260391. 6 interactions.
IntActiP52614. 15 interactions.
STRINGi511145.b1943.

Structurei

3D structure databases

ProteinModelPortaliP52614.
SMRiP52614. Positions 227-336.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domaini

Two-domain protein with the central portion of the sequence acting as a hinge or connector between the two.

Sequence similaritiesi

Belongs to the FliK family.Curated

Phylogenomic databases

eggNOGiENOG4105WF4. Bacteria.
COG3144. LUCA.
HOGENOMiHOG000121331.
InParanoidiP52614.
KOiK02414.
OMAiSHEWQQA.

Family and domain databases

InterProiIPR001635. Flag_hook_Flik.
IPR021136. Flagellar_hook_control-like_C.
[Graphical view]
PfamiPF02120. Flg_hook. 1 hit.
[Graphical view]
PRINTSiPR01007. FLGHOOKFLIK.

Sequencei

Sequence statusi: Complete.

P52614-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIRLAPLITA DVDTTTLPGG KASDAAQDFL ALLSEALAGE TTTDKAAPQL
60 70 80 90 100
LVATDKPTTK GEPLISDIVS DAQQANLLIP VDETPPVIND EQSTSTPLTT
110 120 130 140 150
AQTMALAAVA DKNTTKDEKA DDLNEDVTAS LSALFAMLPG FDNTPKVTDA
160 170 180 190 200
PSTVLPTEKP TLFTKLTSEQ LTTAQPDDAP GTPAQPLTPL VAEAQSKAEV
210 220 230 240 250
ISTPSPVTAA ASPLITPHQT QPLPTVAAPV LSAPLGSHEW QQSLSQHISL
260 270 280 290 300
FTRQGQQSAE LRLHPQDLGE VQISLKVDDN QAQIQMVSPH QHVRAALEAA
310 320 330 340 350
LPVLRTQLAE SGIQLGQSNI SGESFSGQQQ AASQQQQSQR TANHEPLAGE
360 370
DDDTLPVPVS LQGRVTGNSG VDIFA
Length:375
Mass (Da):39,312
Last modified:October 1, 1996 - v1
Checksum:i4C8FCA941FAC7DB3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L43491 Genomic DNA. Translation: AAB06632.1.
L49147 Genomic DNA. Translation: AAA82639.1.
U00096 Genomic DNA. Translation: AAC75010.1.
AP009048 Genomic DNA. Translation: BAA15768.1.
PIRiD64958.
RefSeqiNP_416453.1. NC_000913.3.
WP_000620071.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75010; AAC75010; b1943.
BAA15768; BAA15768; BAA15768.
GeneIDi946449.
KEGGiecj:JW1927.
eco:b1943.
PATRICi32119215. VBIEscCol129921_2022.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L43491 Genomic DNA. Translation: AAB06632.1.
L49147 Genomic DNA. Translation: AAA82639.1.
U00096 Genomic DNA. Translation: AAC75010.1.
AP009048 Genomic DNA. Translation: BAA15768.1.
PIRiD64958.
RefSeqiNP_416453.1. NC_000913.3.
WP_000620071.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP52614.
SMRiP52614. Positions 227-336.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260391. 6 interactions.
IntActiP52614. 15 interactions.
STRINGi511145.b1943.

Proteomic databases

PaxDbiP52614.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75010; AAC75010; b1943.
BAA15768; BAA15768; BAA15768.
GeneIDi946449.
KEGGiecj:JW1927.
eco:b1943.
PATRICi32119215. VBIEscCol129921_2022.

Organism-specific databases

EchoBASEiEB4165.
EcoGeneiEG20268. fliK.

Phylogenomic databases

eggNOGiENOG4105WF4. Bacteria.
COG3144. LUCA.
HOGENOMiHOG000121331.
InParanoidiP52614.
KOiK02414.
OMAiSHEWQQA.

Enzyme and pathway databases

BioCyciEcoCyc:G379-MONOMER.
ECOL316407:JW1927-MONOMER.

Miscellaneous databases

PROiP52614.

Family and domain databases

InterProiIPR001635. Flag_hook_Flik.
IPR021136. Flagellar_hook_control-like_C.
[Graphical view]
PfamiPF02120. Flg_hook. 1 hit.
[Graphical view]
PRINTSiPR01007. FLGHOOKFLIK.
ProtoNetiSearch...

Entry informationi

Entry nameiFLIK_ECOLI
AccessioniPrimary (citable) accession number: P52614
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: September 7, 2016
This is version 103 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.