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P52596 (DHE3_VITVI) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 73. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutamate dehydrogenase

Short name=GDH
EC=1.4.1.3
Gene names
Name:GDH
OrganismVitis vinifera (Grape)
Taxonomic identifier29760 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsVitalesVitaceaeVitis

Protein attributes

Sequence length411 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

L-glutamate + H2O + NAD(P)+ = 2-oxoglutarate + NH3 + NAD(P)H.

Sequence similarities

Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

Ontologies

Keywords
   LigandNAD
   Molecular functionOxidoreductase
Gene Ontology (GO)
   Biological_processcellular amino acid metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionglutamate dehydrogenase [NAD(P)+] activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 411411Glutamate dehydrogenase
PRO_0000182752

Sites

Active site1021 By similarity

Sequences

Sequence LengthMass (Da)Tools
P52596 [UniParc].

Last modified October 1, 1996. Version 1.
Checksum: A6C8F63237CF06B5

FASTA41144,546
        10         20         30         40         50         60 
MNALAATNRN FRHASRILGL DSKLEKSLLI PFREIKVECT IPKDDGSLAT YVGFRVQHDN 

        70         80         90        100        110        120 
ARGPMKGGIR YHPEVDPDEV NALAQLMTWK TAVVDIPYGG AKGGIGCTPK DLSMSELERL 

       130        140        150        160        170        180 
TRVFTQKIHD LIGTHTDVPA PDMGTNAQTM AWILDEYSKF HGHSPAVVTG KPIALGGSLG 

       190        200        210        220        230        240 
REAATGRGVV FATEALLAQH GKSIKGLTFV IQGFGNVGSW VARLIGERGG KIIAVSDVTG 

       250        260        270        280        290        300 
AVKNQNGLDI VDLLRHKEET GCLTNFSGGD HMDPNELLTH ECDVLIPCAL GGVLNKENAA 

       310        320        330        340        350        360 
DVKAKFIIEA ANHPTDPEAD EILSKKGGVI LPDIYANAGG VTVSYFEWVQ NIQGFMWEEE 

       370        380        390        400        410 
KVNNELQKYM TKAFHNIKAM CQSHNCSLRM GAFTLAVNRV ACATTLRGWE A 

« Hide

References

[1]"The amino-acid sequence similarity of plant glutamate dehydrogenase to the extremophilic archaeal enzyme conforms to its stress-related function."
Syntichaki K.M., Loulakakis K.A., Roubelakis-Angelakis K.A.
Gene 168:87-92(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: cv. Sultanina.
Tissue: Shoot.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X86924 mRNA. Translation: CAA60507.1.
PIRS54797.
RefSeqNP_001268039.1. NM_001281110.1.
UniGeneVvi.123.

3D structure databases

ProteinModelPortalP52596.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING29760.GSVIVG00014104001.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID100257914.
KEGGvvi:100257914.

Phylogenomic databases

eggNOGCOG0334.
HOGENOMHOG000243801.
KOK00261.

Family and domain databases

Gene3D3.40.50.720. 1 hit.
InterProIPR006095. Glu/Leu/Phe/Val_DH.
IPR006096. Glu/Leu/Phe/Val_DH_C.
IPR006097. Glu/Leu/Phe/Val_DH_dimer_dom.
IPR014362. Glu_DH.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamPF00208. ELFV_dehydrog. 1 hit.
PF02812. ELFV_dehydrog_N. 1 hit.
[Graphical view]
PIRSFPIRSF000185. Glu_DH. 1 hit.
PRINTSPR00082. GLFDHDRGNASE.
SMARTSM00839. ELFV_dehydrog. 1 hit.
[Graphical view]
PROSITEPS00074. GLFV_DEHYDROGENASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDHE3_VITVI
AccessionPrimary (citable) accession number: P52596
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: February 19, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families