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P52596

- DHE3_VITVI

UniProt

P52596 - DHE3_VITVI

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Protein

Glutamate dehydrogenase

Gene

GDH

Organism
Vitis vinifera (Grape)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

Catalytic activityi

L-glutamate + H2O + NAD(P)+ = 2-oxoglutarate + NH3 + NAD(P)H.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei102 – 1021PROSITE-ProRule annotation

GO - Molecular functioni

  1. glutamate dehydrogenase [NAD(P)+] activity Source: UniProtKB-EC

GO - Biological processi

  1. cellular amino acid metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

NAD

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate dehydrogenase (EC:1.4.1.3)
Short name:
GDH
Gene namesi
Name:GDH
OrganismiVitis vinifera (Grape)
Taxonomic identifieri29760 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsVitalesVitaceaeVitis

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 411411Glutamate dehydrogenasePRO_0000182752Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi29760.GSVIVG00014104001.

Structurei

3D structure databases

ProteinModelPortaliP52596.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0334.
HOGENOMiHOG000243801.
KOiK00261.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR006095. Glu/Leu/Phe/Val_DH.
IPR006096. Glu/Leu/Phe/Val_DH_C.
IPR006097. Glu/Leu/Phe/Val_DH_dimer_dom.
IPR014362. Glu_DH.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF00208. ELFV_dehydrog. 1 hit.
PF02812. ELFV_dehydrog_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000185. Glu_DH. 1 hit.
PRINTSiPR00082. GLFDHDRGNASE.
SMARTiSM00839. ELFV_dehydrog. 1 hit.
[Graphical view]
PROSITEiPS00074. GLFV_DEHYDROGENASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P52596-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNALAATNRN FRHASRILGL DSKLEKSLLI PFREIKVECT IPKDDGSLAT
60 70 80 90 100
YVGFRVQHDN ARGPMKGGIR YHPEVDPDEV NALAQLMTWK TAVVDIPYGG
110 120 130 140 150
AKGGIGCTPK DLSMSELERL TRVFTQKIHD LIGTHTDVPA PDMGTNAQTM
160 170 180 190 200
AWILDEYSKF HGHSPAVVTG KPIALGGSLG REAATGRGVV FATEALLAQH
210 220 230 240 250
GKSIKGLTFV IQGFGNVGSW VARLIGERGG KIIAVSDVTG AVKNQNGLDI
260 270 280 290 300
VDLLRHKEET GCLTNFSGGD HMDPNELLTH ECDVLIPCAL GGVLNKENAA
310 320 330 340 350
DVKAKFIIEA ANHPTDPEAD EILSKKGGVI LPDIYANAGG VTVSYFEWVQ
360 370 380 390 400
NIQGFMWEEE KVNNELQKYM TKAFHNIKAM CQSHNCSLRM GAFTLAVNRV
410
ACATTLRGWE A
Length:411
Mass (Da):44,546
Last modified:October 1, 1996 - v1
Checksum:iA6C8F63237CF06B5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X86924 mRNA. Translation: CAA60507.1.
PIRiS54797.
RefSeqiNP_001268039.1. NM_001281110.1.
UniGeneiVvi.123.

Genome annotation databases

GeneIDi100257914.
KEGGivvi:100257914.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X86924 mRNA. Translation: CAA60507.1 .
PIRi S54797.
RefSeqi NP_001268039.1. NM_001281110.1.
UniGenei Vvi.123.

3D structure databases

ProteinModelPortali P52596.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 29760.GSVIVG00014104001.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 100257914.
KEGGi vvi:100257914.

Phylogenomic databases

eggNOGi COG0334.
HOGENOMi HOG000243801.
KOi K00261.

Family and domain databases

Gene3Di 3.40.50.720. 1 hit.
InterProi IPR006095. Glu/Leu/Phe/Val_DH.
IPR006096. Glu/Leu/Phe/Val_DH_C.
IPR006097. Glu/Leu/Phe/Val_DH_dimer_dom.
IPR014362. Glu_DH.
IPR016040. NAD(P)-bd_dom.
[Graphical view ]
Pfami PF00208. ELFV_dehydrog. 1 hit.
PF02812. ELFV_dehydrog_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000185. Glu_DH. 1 hit.
PRINTSi PR00082. GLFDHDRGNASE.
SMARTi SM00839. ELFV_dehydrog. 1 hit.
[Graphical view ]
PROSITEi PS00074. GLFV_DEHYDROGENASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The amino-acid sequence similarity of plant glutamate dehydrogenase to the extremophilic archaeal enzyme conforms to its stress-related function."
    Syntichaki K.M., Loulakakis K.A., Roubelakis-Angelakis K.A.
    Gene 168:87-92(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: cv. Sultanina.
    Tissue: Shoot.

Entry informationi

Entry nameiDHE3_VITVI
AccessioniPrimary (citable) accession number: P52596
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: October 1, 2014
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3