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P52596

- DHE3_VITVI

UniProt

P52596 - DHE3_VITVI

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Protein
Glutamate dehydrogenase
Gene
GDH
Organism
Vitis vinifera (Grape)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Catalytic activityi

L-glutamate + H2O + NAD(P)+ = 2-oxoglutarate + NH3 + NAD(P)H.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei102 – 1021 By similarity

GO - Molecular functioni

  1. glutamate dehydrogenase [NAD(P)+] activity Source: UniProtKB-EC

GO - Biological processi

  1. cellular amino acid metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

NAD

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate dehydrogenase (EC:1.4.1.3)
Short name:
GDH
Gene namesi
Name:GDH
OrganismiVitis vinifera (Grape)
Taxonomic identifieri29760 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsVitalesVitaceaeVitis

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 411411Glutamate dehydrogenase
PRO_0000182752Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi29760.GSVIVG00014104001.

Structurei

3D structure databases

ProteinModelPortaliP52596.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0334.
HOGENOMiHOG000243801.
KOiK00261.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR006095. Glu/Leu/Phe/Val_DH.
IPR006096. Glu/Leu/Phe/Val_DH_C.
IPR006097. Glu/Leu/Phe/Val_DH_dimer_dom.
IPR014362. Glu_DH.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF00208. ELFV_dehydrog. 1 hit.
PF02812. ELFV_dehydrog_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000185. Glu_DH. 1 hit.
PRINTSiPR00082. GLFDHDRGNASE.
SMARTiSM00839. ELFV_dehydrog. 1 hit.
[Graphical view]
PROSITEiPS00074. GLFV_DEHYDROGENASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P52596-1 [UniParc]FASTAAdd to Basket

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MNALAATNRN FRHASRILGL DSKLEKSLLI PFREIKVECT IPKDDGSLAT    50
YVGFRVQHDN ARGPMKGGIR YHPEVDPDEV NALAQLMTWK TAVVDIPYGG 100
AKGGIGCTPK DLSMSELERL TRVFTQKIHD LIGTHTDVPA PDMGTNAQTM 150
AWILDEYSKF HGHSPAVVTG KPIALGGSLG REAATGRGVV FATEALLAQH 200
GKSIKGLTFV IQGFGNVGSW VARLIGERGG KIIAVSDVTG AVKNQNGLDI 250
VDLLRHKEET GCLTNFSGGD HMDPNELLTH ECDVLIPCAL GGVLNKENAA 300
DVKAKFIIEA ANHPTDPEAD EILSKKGGVI LPDIYANAGG VTVSYFEWVQ 350
NIQGFMWEEE KVNNELQKYM TKAFHNIKAM CQSHNCSLRM GAFTLAVNRV 400
ACATTLRGWE A 411
Length:411
Mass (Da):44,546
Last modified:October 1, 1996 - v1
Checksum:iA6C8F63237CF06B5
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X86924 mRNA. Translation: CAA60507.1.
PIRiS54797.
RefSeqiNP_001268039.1. NM_001281110.1.
UniGeneiVvi.123.

Genome annotation databases

GeneIDi100257914.
KEGGivvi:100257914.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X86924 mRNA. Translation: CAA60507.1 .
PIRi S54797.
RefSeqi NP_001268039.1. NM_001281110.1.
UniGenei Vvi.123.

3D structure databases

ProteinModelPortali P52596.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 29760.GSVIVG00014104001.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 100257914.
KEGGi vvi:100257914.

Phylogenomic databases

eggNOGi COG0334.
HOGENOMi HOG000243801.
KOi K00261.

Family and domain databases

Gene3Di 3.40.50.720. 1 hit.
InterProi IPR006095. Glu/Leu/Phe/Val_DH.
IPR006096. Glu/Leu/Phe/Val_DH_C.
IPR006097. Glu/Leu/Phe/Val_DH_dimer_dom.
IPR014362. Glu_DH.
IPR016040. NAD(P)-bd_dom.
[Graphical view ]
Pfami PF00208. ELFV_dehydrog. 1 hit.
PF02812. ELFV_dehydrog_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000185. Glu_DH. 1 hit.
PRINTSi PR00082. GLFDHDRGNASE.
SMARTi SM00839. ELFV_dehydrog. 1 hit.
[Graphical view ]
PROSITEi PS00074. GLFV_DEHYDROGENASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The amino-acid sequence similarity of plant glutamate dehydrogenase to the extremophilic archaeal enzyme conforms to its stress-related function."
    Syntichaki K.M., Loulakakis K.A., Roubelakis-Angelakis K.A.
    Gene 168:87-92(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: cv. Sultanina.
    Tissue: Shoot.

Entry informationi

Entry nameiDHE3_VITVI
AccessioniPrimary (citable) accession number: P52596
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: February 19, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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