Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P52588

- PDI_MAIZE

UniProt

P52588 - PDI_MAIZE

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Protein disulfide-isomerase

Gene

PDI

Organism
Zea mays (Maize)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

Participates in the folding of proteins containing disulfide bonds, may be involved in glycosylation, prolyl hydroxylation and triglyceride transfer.By similarity

Catalytic activityi

Catalyzes the rearrangement of -S-S- bonds in proteins.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei63 – 631NucleophileBy similarity
Sitei64 – 641Contributes to redox potential valueBy similarity
Sitei65 – 651Contributes to redox potential valueBy similarity
Active sitei66 – 661NucleophileBy similarity
Sitei131 – 1311Lowers pKa of C-terminal Cys of first active siteBy similarity
Active sitei408 – 4081NucleophileBy similarity
Sitei409 – 4091Contributes to redox potential valueBy similarity
Sitei410 – 4101Contributes to redox potential valueBy similarity
Active sitei411 – 4111NucleophileBy similarity
Sitei471 – 4711Lowers pKa of C-terminal Cys of second active siteBy similarity

GO - Molecular functioni

  1. protein disulfide isomerase activity Source: UniProtKB-EC

GO - Biological processi

  1. cell redox homeostasis Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Names & Taxonomyi

Protein namesi
Recommended name:
Protein disulfide-isomerase (EC:5.3.4.1)
Short name:
PDI
Gene namesi
Name:PDI
OrganismiZea mays (Maize)
Taxonomic identifieri4577 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaePACMAD cladePanicoideaeAndropogoneaeZea

Organism-specific databases

GrameneiP52588.
MaizeGDBi86830.

Subcellular locationi

Endoplasmic reticulum lumen PROSITE-ProRule annotation

GO - Cellular componenti

  1. endoplasmic reticulum Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2323By similarityAdd
BLAST
Chaini24 – 513490Protein disulfide-isomerasePRO_0000034210Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi63 ↔ 66Redox-activePROSITE-ProRule annotation
Glycosylationi279 – 2791N-linked (GlcNAc...)Sequence Analysis
Disulfide bondi408 ↔ 411Redox-activePROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PRIDEiP52588.

Structurei

3D structure databases

ProteinModelPortaliP52588.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini24 – 145122Thioredoxin 1PROSITE-ProRule annotationAdd
BLAST
Domaini366 – 485120Thioredoxin 2PROSITE-ProRule annotationAdd
BLAST

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi510 – 5134Prevents secretion from ERPROSITE-ProRule annotation

Sequence similaritiesi

Belongs to the protein disulfide isomerase family.Curated
Contains 2 thioredoxin domains.PROSITE-ProRule annotation

Keywords - Domaini

Redox-active center, Repeat, Signal

Family and domain databases

Gene3Di3.40.30.10. 3 hits.
InterProiIPR005788. Disulphide_isomerase.
IPR005792. Prot_disulphide_isomerase.
IPR012336. Thioredoxin-like_fold.
IPR017937. Thioredoxin_CS.
IPR013766. Thioredoxin_domain.
[Graphical view]
PfamiPF00085. Thioredoxin. 2 hits.
[Graphical view]
SUPFAMiSSF52833. SSF52833. 4 hits.
TIGRFAMsiTIGR01130. ER_PDI_fam. 1 hit.
TIGR01126. pdi_dom. 2 hits.
PROSITEiPS00014. ER_TARGET. 1 hit.
PS00194. THIOREDOXIN_1. 2 hits.
PS51352. THIOREDOXIN_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P52588-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAIRSKAWIS LLLALAVALS ARAEEEPAAA AEGEAVLTLD VDSFDEAVAK
60 70 80 90 100
HPFMVVEFYA PWCGHCKKLA PEYENAAKAL SKHDPPIVLA KVDANEEKNR
110 120 130 140 150
PLATKYEIQG FPTIKIFRDR GKNIQEYKGP READGIVDYL KKQVGPASKE
160 170 180 190 200
IKSPEDATAL IDDKKIYIVG IFAEFSGTEF TNFMEVAEKL RSDYDFGHTL
210 220 230 240 250
HANHLPRGDA AVERPLVRLL KPFDELVVDS KDFDVAALMK FIDASTIPRV
260 270 280 290 300
VTFDKNPDNH PYLMKFFQSS APKAMLFLNF STGPFDSFKS AYSAAAEEFK
310 320 330 340 350
DKEIKFLIGD IEASQGAFQY FGLKEDQTPL ILIQDGDSKK FLKVHVEADQ
360 370 380 390 400
IVAWLKEYFD GKLTPFRNSE PIPEVNNEPV KVVVADNVHD FVFKSGKNVL
410 420 430 440 450
IEFYAPWCGH CKKLAPILDE AATTLQSDEE VVIAKMDATA NDVPSEFDVQ
460 470 480 490 500
GYPTLYFVTP SGKVTSYDSG RTADDIVDFI KKSKETAAPH HHHHPGATGI
510
REGSRAEPVK DEL
Length:513
Mass (Da):57,097
Last modified:October 1, 1996 - v1
Checksum:i29302DD01A3DEB80
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L39014 mRNA. Translation: AAB08519.1.
PIRiS69181.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L39014 mRNA. Translation: AAB08519.1 .
PIRi S69181.

3D structure databases

ProteinModelPortali P52588.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi P52588.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

Gramenei P52588.
MaizeGDBi 86830.

Family and domain databases

Gene3Di 3.40.30.10. 3 hits.
InterProi IPR005788. Disulphide_isomerase.
IPR005792. Prot_disulphide_isomerase.
IPR012336. Thioredoxin-like_fold.
IPR017937. Thioredoxin_CS.
IPR013766. Thioredoxin_domain.
[Graphical view ]
Pfami PF00085. Thioredoxin. 2 hits.
[Graphical view ]
SUPFAMi SSF52833. SSF52833. 4 hits.
TIGRFAMsi TIGR01130. ER_PDI_fam. 1 hit.
TIGR01126. pdi_dom. 2 hits.
PROSITEi PS00014. ER_TARGET. 1 hit.
PS00194. THIOREDOXIN_1. 2 hits.
PS51352. THIOREDOXIN_2. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Expression of protein disulfide isomerase is elevated in the endosperm of the maize floury-2 mutant."
    Li C.P., Larkins B.A.
    Plant Mol. Biol. 30:873-882(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: cv. Wisconsin 64A.
    Tissue: Endosperm.

Entry informationi

Entry nameiPDI_MAIZE
AccessioniPrimary (citable) accession number: P52588
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: October 29, 2014
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3