##gff-version 3
P52565	UniProtKB	Initiator methionine	1	1	.	.	.	Note=Removed;Ontology_term=ECO:0000269,ECO:0007744,ECO:0007744;evidence=ECO:0000269|Ref.12,ECO:0007744|PubMed:19413330,ECO:0007744|PubMed:20068231;Dbxref=PMID:19413330,PMID:20068231	
P52565	UniProtKB	Chain	2	204	.	.	.	ID=PRO_0000219013;Note=Rho GDP-dissociation inhibitor 1	
P52565	UniProtKB	Region	1	36	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P52565	UniProtKB	Modified residue	2	2	.	.	.	Note=N-acetylalanine;Ontology_term=ECO:0000269,ECO:0007744,ECO:0007744;evidence=ECO:0000269|Ref.12,ECO:0007744|PubMed:19413330,ECO:0007744|PubMed:20068231;Dbxref=PMID:19413330,PMID:20068231	
P52565	UniProtKB	Modified residue	34	34	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q99PT1	
P52565	UniProtKB	Modified residue	43	43	.	.	.	Note=N6-acetyllysine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q99PT1	
P52565	UniProtKB	Modified residue	47	47	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:23186163;Dbxref=PMID:23186163	
P52565	UniProtKB	Modified residue	105	105	.	.	.	Note=N6-acetyllysine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:19608861;Dbxref=PMID:19608861	
P52565	UniProtKB	Modified residue	127	127	.	.	.	Note=N6-acetyllysine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:19608861;Dbxref=PMID:19608861	
P52565	UniProtKB	Modified residue	141	141	.	.	.	Note=N6-acetyllysine%3B alternate;Ontology_term=ECO:0007744,ECO:0007744;evidence=ECO:0007744|PubMed:16916647,ECO:0007744|PubMed:19608861;Dbxref=PMID:16916647,PMID:19608861	
P52565	UniProtKB	Modified residue	141	141	.	.	.	Note=N6-succinyllysine%3B alternate;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q99PT1	
P52565	UniProtKB	Modified residue	178	178	.	.	.	Note=N6-acetyllysine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:19608861;Dbxref=PMID:19608861	
P52565	UniProtKB	Cross-link	138	138	.	.	.	Note=Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)%3B alternate;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:25114211;Dbxref=PMID:25114211	
P52565	UniProtKB	Cross-link	138	138	.	.	.	Note=Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)%3B alternate;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:25114211;Dbxref=PMID:25114211	
P52565	UniProtKB	Cross-link	141	141	.	.	.	Note=Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)%3B alternate;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:25114211;Dbxref=PMID:25114211	
P52565	UniProtKB	Cross-link	141	141	.	.	.	Note=Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)%3B alternate;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:25114211;Dbxref=PMID:25114211	
P52565	UniProtKB	Alternative sequence	139	183	.	.	.	ID=VSP_046699;Note=In isoform 2. IDKTDYMVGSYGPRAEEYEFLTPVEEAPKGMLARGSYSIKSRFTD->N;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039	
P52565	UniProtKB	Natural variant	185	185	.	.	.	ID=VAR_069814;Note=In NPHS8%3B produces mislocalization into the nucleus%2C hyperactivation of Rho-GTPases RHOA%2C RAC1 and CDC42 and impaired cell motility. Missing;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:23434736;Dbxref=PMID:23434736	
P52565	UniProtKB	Mutagenesis	45	45	.	.	.	Note=Loss of RHOA interaction%3B when associated with A-185. D->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:20400958;Dbxref=PMID:20400958	
P52565	UniProtKB	Mutagenesis	99	99	.	.	.	Note=Loss of interaction with NGFR. K->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:26646181;Dbxref=PMID:26646181	
P52565	UniProtKB	Mutagenesis	185	185	.	.	.	Note=Loss of RHOA interaction%3B when associated with A-45. D->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:20400958;Dbxref=PMID:20400958	
P52565	UniProtKB	Mutagenesis	199	199	.	.	.	Note=Loss of interaction with NGFR. K->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:26646181;Dbxref=PMID:26646181	
P52565	UniProtKB	Sequence conflict	139	139	.	.	.	Note=I->V;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P52565	UniProtKB	Sequence conflict	188	188	.	.	.	Note=D->R;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P52565	UniProtKB	Helix	35	39	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1HH4	
P52565	UniProtKB	Helix	46	56	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1HH4	
P52565	UniProtKB	Turn	59	63	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:2N80	
P52565	UniProtKB	Beta strand	69	78	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1KMT	
P52565	UniProtKB	Beta strand	82	84	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1KMT	
P52565	UniProtKB	Beta strand	87	89	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1KMT	
P52565	UniProtKB	Helix	94	99	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1KMT	
P52565	UniProtKB	Beta strand	102	105	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1KMT	
P52565	UniProtKB	Beta strand	109	118	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1KMT	
P52565	UniProtKB	Beta strand	123	134	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1KMT	
P52565	UniProtKB	Beta strand	137	149	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1KMT	
P52565	UniProtKB	Beta strand	156	159	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1KMT	
P52565	UniProtKB	Turn	169	171	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1KMT	
P52565	UniProtKB	Beta strand	173	182	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1KMT	
P52565	UniProtKB	Beta strand	189	200	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1KMT