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P52563

- TRPF_HALVD

UniProt

P52563 - TRPF_HALVD

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Protein

N-(5'-phosphoribosyl)anthranilate isomerase

Gene

trpF

Organism
Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.

Pathwayi

GO - Molecular functioni

  1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC

GO - Biological processi

  1. tryptophan biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

Enzyme and pathway databases

BioCyciHVOL309800:GCOK-2458-MONOMER.
UniPathwayiUPA00035; UER00042.

Names & Taxonomyi

Protein namesi
Recommended name:
N-(5'-phosphoribosyl)anthranilate isomerase (EC:5.3.1.24)
Short name:
PRAI
Gene namesi
Name:trpF
Ordered Locus Names:HVO_2455
OrganismiHaloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii)
Taxonomic identifieri309800 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHaloferax
ProteomesiUP000008243: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 221221N-(5'-phosphoribosyl)anthranilate isomerasePRO_0000154401Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP52563.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TrpF family.Curated

Phylogenomic databases

HOGENOMiHOG000161598.
KOiK01817.
OMAiETHDWER.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00135. PRAI.
InterProiIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.

Sequencei

Sequence statusi: Complete.

P52563-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTRVKVCGVT DETDLAAVDA AGADAVGAIC DVPVDTPREI PRERARELFA
60 70 80 90 100
AAPPFLTTTL VTMPDSVDHA RDLAREVGPD VLQLHGDFAA DDLDSLRATG
110 120 130 140 150
VGVVPVVDAT DLARARDLAP VVDAILVDTP SDSGAGGTGE THDWDASRDL
160 170 180 190 200
VAAVDAPVIL AGGLTPDNVV EAVRTVEPYG VDVASGVEAS GGVKDHDAVR
210 220
AFVAAAKTAR GAVDDHEEVV A
Length:221
Mass (Da):22,634
Last modified:October 1, 1996 - v1
Checksum:i396453808C71FBAD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M83788 Genomic DNA. Translation: AAA73176.1.
CP001956 Genomic DNA. Translation: ADE04719.1.
RefSeqiWP_004042369.1. NZ_AOHU01000044.1.
YP_003536476.1. NC_013967.1.

Genome annotation databases

EnsemblBacteriaiADE04719; ADE04719; HVO_2455.
GeneIDi8924041.
KEGGihvo:HVO_2455.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M83788 Genomic DNA. Translation: AAA73176.1 .
CP001956 Genomic DNA. Translation: ADE04719.1 .
RefSeqi WP_004042369.1. NZ_AOHU01000044.1.
YP_003536476.1. NC_013967.1.

3D structure databases

ProteinModelPortali P52563.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADE04719 ; ADE04719 ; HVO_2455 .
GeneIDi 8924041.
KEGGi hvo:HVO_2455.

Phylogenomic databases

HOGENOMi HOG000161598.
KOi K01817.
OMAi ETHDWER.

Enzyme and pathway databases

UniPathwayi UPA00035 ; UER00042 .
BioCyci HVOL309800:GCOK-2458-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00135. PRAI.
InterProi IPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view ]
Pfami PF00697. PRAI. 1 hit.
[Graphical view ]
SUPFAMi SSF51366. SSF51366. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Genes for tryptophan biosynthesis in the halophilic archaebacterium Haloferax volcanii: the trpDFEG cluster."
    Lam W.L., Logan S.M., Doolittle W.F.
    J. Bacteriol. 174:1694-1697(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: DS2 / DSM 5716 / WFD11.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2.

Entry informationi

Entry nameiTRPF_HALVD
AccessioniPrimary (citable) accession number: P52563
Secondary accession number(s): D4GT39
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: October 1, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3