Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P52563

- TRPF_HALVD

UniProt

P52563 - TRPF_HALVD

Protein

N-(5'-phosphoribosyl)anthranilate isomerase

Gene

trpF

Organism
Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 64 (01 Oct 2014)
      Sequence version 1 (01 Oct 1996)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.

    Pathwayi

    GO - Molecular functioni

    1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC

    GO - Biological processi

    1. tryptophan biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

    Enzyme and pathway databases

    BioCyciHVOL309800:GCOK-2458-MONOMER.
    UniPathwayiUPA00035; UER00042.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    N-(5'-phosphoribosyl)anthranilate isomerase (EC:5.3.1.24)
    Short name:
    PRAI
    Gene namesi
    Name:trpF
    Ordered Locus Names:HVO_2455
    OrganismiHaloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii)
    Taxonomic identifieri309800 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHaloferax
    ProteomesiUP000008243: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 221221N-(5'-phosphoribosyl)anthranilate isomerasePRO_0000154401Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliP52563.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the TrpF family.Curated

    Phylogenomic databases

    HOGENOMiHOG000161598.
    KOiK01817.
    OMAiETHDWER.

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    HAMAPiMF_00135. PRAI.
    InterProiIPR013785. Aldolase_TIM.
    IPR001240. PRAI_dom.
    IPR011060. RibuloseP-bd_barrel.
    [Graphical view]
    PfamiPF00697. PRAI. 1 hit.
    [Graphical view]
    SUPFAMiSSF51366. SSF51366. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P52563-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTRVKVCGVT DETDLAAVDA AGADAVGAIC DVPVDTPREI PRERARELFA    50
    AAPPFLTTTL VTMPDSVDHA RDLAREVGPD VLQLHGDFAA DDLDSLRATG 100
    VGVVPVVDAT DLARARDLAP VVDAILVDTP SDSGAGGTGE THDWDASRDL 150
    VAAVDAPVIL AGGLTPDNVV EAVRTVEPYG VDVASGVEAS GGVKDHDAVR 200
    AFVAAAKTAR GAVDDHEEVV A 221
    Length:221
    Mass (Da):22,634
    Last modified:October 1, 1996 - v1
    Checksum:i396453808C71FBAD
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M83788 Genomic DNA. Translation: AAA73176.1.
    CP001956 Genomic DNA. Translation: ADE04719.1.
    RefSeqiWP_004042369.1. NZ_AOHU01000044.1.
    YP_003536476.1. NC_013967.1.

    Genome annotation databases

    EnsemblBacteriaiADE04719; ADE04719; HVO_2455.
    GeneIDi8924041.
    KEGGihvo:HVO_2455.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M83788 Genomic DNA. Translation: AAA73176.1 .
    CP001956 Genomic DNA. Translation: ADE04719.1 .
    RefSeqi WP_004042369.1. NZ_AOHU01000044.1.
    YP_003536476.1. NC_013967.1.

    3D structure databases

    ProteinModelPortali P52563.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADE04719 ; ADE04719 ; HVO_2455 .
    GeneIDi 8924041.
    KEGGi hvo:HVO_2455.

    Phylogenomic databases

    HOGENOMi HOG000161598.
    KOi K01817.
    OMAi ETHDWER.

    Enzyme and pathway databases

    UniPathwayi UPA00035 ; UER00042 .
    BioCyci HVOL309800:GCOK-2458-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    HAMAPi MF_00135. PRAI.
    InterProi IPR013785. Aldolase_TIM.
    IPR001240. PRAI_dom.
    IPR011060. RibuloseP-bd_barrel.
    [Graphical view ]
    Pfami PF00697. PRAI. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51366. SSF51366. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Genes for tryptophan biosynthesis in the halophilic archaebacterium Haloferax volcanii: the trpDFEG cluster."
      Lam W.L., Logan S.M., Doolittle W.F.
      J. Bacteriol. 174:1694-1697(1992) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: DS2 / DSM 5716 / WFD11.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2.

    Entry informationi

    Entry nameiTRPF_HALVD
    AccessioniPrimary (citable) accession number: P52563
    Secondary accession number(s): D4GT39
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 1, 1996
    Last sequence update: October 1, 1996
    Last modified: October 1, 2014
    This is version 64 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3