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P52563 (TRPF_HALVD) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
N-(5'-phosphoribosyl)anthranilate isomerase

Short name=PRAI
EC=5.3.1.24
Gene names
Name:trpF
Ordered Locus Names:HVO_2455
OrganismHaloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) [Reference proteome] [HAMAP]
Taxonomic identifier309800 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHaloferax

Protein attributes

Sequence length221 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate. HAMAP-Rule MF_00135

Pathway

Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5. HAMAP-Rule MF_00135

Sequence similarities

Belongs to the TrpF family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 221221N-(5'-phosphoribosyl)anthranilate isomerase HAMAP-Rule MF_00135
PRO_0000154401

Sequences

Sequence LengthMass (Da)Tools
P52563 [UniParc].

Last modified October 1, 1996. Version 1.
Checksum: 396453808C71FBAD

FASTA22122,634
        10         20         30         40         50         60 
MTRVKVCGVT DETDLAAVDA AGADAVGAIC DVPVDTPREI PRERARELFA AAPPFLTTTL 

        70         80         90        100        110        120 
VTMPDSVDHA RDLAREVGPD VLQLHGDFAA DDLDSLRATG VGVVPVVDAT DLARARDLAP 

       130        140        150        160        170        180 
VVDAILVDTP SDSGAGGTGE THDWDASRDL VAAVDAPVIL AGGLTPDNVV EAVRTVEPYG 

       190        200        210        220 
VDVASGVEAS GGVKDHDAVR AFVAAAKTAR GAVDDHEEVV A 

« Hide

References

« Hide 'large scale' references
[1]"Genes for tryptophan biosynthesis in the halophilic archaebacterium Haloferax volcanii: the trpDFEG cluster."
Lam W.L., Logan S.M., Doolittle W.F.
J. Bacteriol. 174:1694-1697(1992) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: DS2 / WFD11.
[2]"The complete genome sequence of Haloferax volcanii DS2, a model archaeon."
Hartman A.L., Norais C., Badger J.H., Delmas S., Haldenby S., Madupu R., Robinson J., Khouri H., Ren Q., Lowe T.M., Maupin-Furlow J., Pohlschroder M., Daniels C., Pfeiffer F., Allers T., Eisen J.A.
PLoS ONE 5:E9605-E9605(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M83788 Genomic DNA. Translation: AAA73176.1.
CP001956 Genomic DNA. Translation: ADE04719.1.
RefSeqYP_003536476.1. NC_013967.1.

3D structure databases

ProteinModelPortalP52563.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADE04719; ADE04719; HVO_2455.
GeneID8924041.
KEGGhvo:HVO_2455.

Phylogenomic databases

HOGENOMHOG000161598.
KOK01817.
OMAETHDWER.

Enzyme and pathway databases

BioCycHVOL309800:GCOK-2458-MONOMER.
UniPathwayUPA00035; UER00042.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
HAMAPMF_00135. PRAI.
InterProIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMSSF51366. SSF51366. 1 hit.
ProtoNetSearch...

Entry information

Entry nameTRPF_HALVD
AccessionPrimary (citable) accession number: P52563
Secondary accession number(s): D4GT39
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: February 19, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways