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P52563

- TRPF_HALVD

UniProt

P52563 - TRPF_HALVD

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Protein
N-(5'-phosphoribosyl)anthranilate isomerase
Gene
trpF, HVO_2455
Organism
Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC

GO - Biological processi

  1. tryptophan biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

Enzyme and pathway databases

BioCyciHVOL309800:GCOK-2458-MONOMER.
UniPathwayiUPA00035; UER00042.

Names & Taxonomyi

Protein namesi
Recommended name:
N-(5'-phosphoribosyl)anthranilate isomerase (EC:5.3.1.24)
Short name:
PRAI
Gene namesi
Name:trpF
Ordered Locus Names:HVO_2455
OrganismiHaloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii)
Taxonomic identifieri309800 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHaloferax
ProteomesiUP000008243: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 221221N-(5'-phosphoribosyl)anthranilate isomeraseUniRule annotation
PRO_0000154401Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP52563.

Family & Domainsi

Sequence similaritiesi

Belongs to the TrpF family.

Phylogenomic databases

HOGENOMiHOG000161598.
KOiK01817.
OMAiETHDWER.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00135. PRAI.
InterProiIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.

Sequencei

Sequence statusi: Complete.

P52563-1 [UniParc]FASTAAdd to Basket

« Hide

MTRVKVCGVT DETDLAAVDA AGADAVGAIC DVPVDTPREI PRERARELFA    50
AAPPFLTTTL VTMPDSVDHA RDLAREVGPD VLQLHGDFAA DDLDSLRATG 100
VGVVPVVDAT DLARARDLAP VVDAILVDTP SDSGAGGTGE THDWDASRDL 150
VAAVDAPVIL AGGLTPDNVV EAVRTVEPYG VDVASGVEAS GGVKDHDAVR 200
AFVAAAKTAR GAVDDHEEVV A 221
Length:221
Mass (Da):22,634
Last modified:October 1, 1996 - v1
Checksum:i396453808C71FBAD
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M83788 Genomic DNA. Translation: AAA73176.1.
CP001956 Genomic DNA. Translation: ADE04719.1.
RefSeqiWP_004042369.1. NZ_AOHU01000044.1.
YP_003536476.1. NC_013967.1.

Genome annotation databases

EnsemblBacteriaiADE04719; ADE04719; HVO_2455.
GeneIDi8924041.
KEGGihvo:HVO_2455.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M83788 Genomic DNA. Translation: AAA73176.1 .
CP001956 Genomic DNA. Translation: ADE04719.1 .
RefSeqi WP_004042369.1. NZ_AOHU01000044.1.
YP_003536476.1. NC_013967.1.

3D structure databases

ProteinModelPortali P52563.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADE04719 ; ADE04719 ; HVO_2455 .
GeneIDi 8924041.
KEGGi hvo:HVO_2455.

Phylogenomic databases

HOGENOMi HOG000161598.
KOi K01817.
OMAi ETHDWER.

Enzyme and pathway databases

UniPathwayi UPA00035 ; UER00042 .
BioCyci HVOL309800:GCOK-2458-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00135. PRAI.
InterProi IPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view ]
Pfami PF00697. PRAI. 1 hit.
[Graphical view ]
SUPFAMi SSF51366. SSF51366. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Genes for tryptophan biosynthesis in the halophilic archaebacterium Haloferax volcanii: the trpDFEG cluster."
    Lam W.L., Logan S.M., Doolittle W.F.
    J. Bacteriol. 174:1694-1697(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: DS2 / DSM 5716 / WFD11.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2.

Entry informationi

Entry nameiTRPF_HALVD
AccessioniPrimary (citable) accession number: P52563
Secondary accession number(s): D4GT39
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: September 3, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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