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Reviewed, UniProtKB/Swiss-Prot P52492 (UBC11_YEAST)

Last modified February 9, 2010. Version 78. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Ubiquitin-conjugating enzyme E2-18 kDa
    EC=6.3.2.19
Alternative name(s):
    Ubiquitin-protein ligase
    Ubiquitin carrier protein
Gene names
Name: UBC11
Ordered Locus Names: YOR339C
ORF Names: O6268
OrganismSaccharomyces cerevisiae (Baker's yeast) [Complete proteome]
Taxonomic identifier4932 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length156 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level.

General annotation (Comments)

Function

Catalyzes the covalent attachment of ubiquitin to other proteins By similarity.

Catalytic activity

ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.

Pathway

Protein modification; protein ubiquitination.

Sequence similarities

Belongs to the ubiquitin-conjugating enzyme family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 156156Ubiquitin-conjugating enzyme E2-18 kDa
PRO_0000082559

Sites

Active site931Glycyl thioester intermediate By similarity

Sequences

Sequence LengthMass (Da)Tools
P52492-1 [UniParc].

Last modified October 1, 1996. Version 1.
Checksum: 950C69F224900197

FASTA15617,753
        10         20         30         40         50         60 
MAVEEGGCVT KRLQNELLQL LSSTTESISA FPVDDNDLTY WVGYITGPKD TPYSGLKFKV 

        70         80         90        100        110        120 
SLKFPQNYPF HPPMIKFLSP MWHPNVDKSG NICLDILKEK WSAVYNVETI LLSLQSLLGE 

       130        140        150 
PNNRSPLNAV AAELWDADME EYRKKVLACY EEIDDY 

« Hide

References

« Hide 'large scale' references
[1]"Nucleotide sequence analysis of a 40 kb segment on the right arm of yeast chromosome XV reveals 18 open reading frames including a new pyruvate kinase and three homologues to chromosome I genes."
Purnelle B., Goffeau A.
Yeast 12:1475-1481(1996) [PubMed: 8948102] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 90843 / S288c / FY73.
[2]"The nucleotide sequence of Saccharomyces cerevisiae chromosome XV."
Dujon B., Albermann K., Aldea M., Alexandraki D., Ansorge W., Arino J., Benes V., Bohn C., Bolotin-Fukuhara M., Bordonne R., Boyer J., Camasses A., Casamayor A., Casas C., Cheret G., Cziepluch C., Daignan-Fornier B., Dang V.-D. expand/collapse author list , de Haan M., Delius H., Durand P., Fairhead C., Feldmann H., Gaillon L., Galisson F., Gamo F.-J., Gancedo C., Goffeau A., Goulding S.E., Grivell L.A., Habbig B., Hand N.J., Hani J., Hattenhorst U., Hebling U., Hernando Y., Herrero E., Heumann K., Hiesel R., Hilger F., Hofmann B., Hollenberg C.P., Hughes B., Jauniaux J.-C., Kalogeropoulos A., Katsoulou C., Kordes E., Lafuente M.J., Landt O., Louis E.J., Maarse A.C., Madania A., Mannhaupt G., Marck C., Martin R.P., Mewes H.-W., Michaux G., Paces V., Parle-McDermott A.G., Pearson B.M., Perrin A., Pettersson B., Poch O., Pohl T.M., Poirey R., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rechmann S., Schwager C., Schweizer M., Sor F., Sterky F., Tarassov I.A., Teodoru C., Tettelin H., Thierry A., Tobiasch E., Tzermia M., Uhlen M., Unseld M., Valens M., Vandenbol M., Vetter I., Vlcek C., Voet M., Volckaert G., Voss H., Wambutt R., Wedler H., Wiemann S., Winsor B., Wolfe K.H., Zollner A., Zumstein E., Kleine K.
Nature 387:98-102(1997) [PubMed: 9169874] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 96604 / S288c / FY1679.
[3]"Functional analysis of the Saccharomyces cerevisiae UBC11 gene."
Townsley F.M., Ruderman J.V.
Yeast 14:747-757(1998) [PubMed: 9675819] [Abstract]
Cited for: CHARACTERIZATION.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X95720 Genomic DNA. Translation: CAA65027.1.
Z75247 Genomic DNA. Translation: CAA99663.1.
PIRS67248.
RefSeqNP_014984.1.

3D structure databases

SMRP52492. Positions 4-144.
ModBaseSearch...

Protein-protein interaction databases

DIPDIP-7221N.
IntActP52492. 1 interaction.
STRINGP52492.

Genome annotation databases

EnsemblYOR339C; YOR339C; YOR339C; Saccharomyces cerevisiae. [Genome view]
GeneID854517.
KEGGsce:YOR339C.
NMPDRfig|4932.3.peg.6101.

Organism-specific databases

CYGDYOR339c.
SGDS000005866. UBC11.

Phylogenomic databases

eggNOGfuNOG09388.
HOGENOMHBG756483.
OMAKEKWSAV.
OrthoDBEOG93JDNM.
PhylomeDBP52492.

Enzyme and pathway databases

BRENDA6.3.2.19. 250.

Gene expression databases

ArrayExpressP52492.
GenevestigatorP52492.
GermOnlineYOR339C. Saccharomyces cerevisiae.

Family and domain databases

InterProIPR015582. Ubiquitin-conj_enz_E2_H10.
IPR016135. UBQ-conjugat/RWD-like.
IPR000608. UBQ-conjugat_E2.
[Graphical view]
Gene3DG3DSA:3.10.110.10. UBQ-conjugat_E2. 1 hit.
PANTHERPTHR11621:SF26. UbcH10. 1 hit.
PfamPF00179. UQ_con. 1 hit.
[Graphical view]
SMARTSM00212. UBCc. 1 hit.
[Graphical view]
PROSITEPS00183. UBIQUITIN_CONJUGAT_1. 1 hit.
PS50127. UBIQUITIN_CONJUGAT_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other Resources

NextBio976882.

Entry information

Entry nameUBC11_YEAST
AccessionPrimary (citable) accession number: P52492
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: February 9, 2010
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectFPAP (Fungal Proteome Annotation Project)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents