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Reviewed, UniProtKB/Swiss-Prot P52484 (UBC21_CAEEL)

Last modified November 25, 2008. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Probable ubiquitin-conjugating enzyme E2 21
    EC=6.3.2.19
Alternative name(s):
    Ubiquitin-protein ligase 21
    Ubiquitin carrier protein 21
Gene names
Name: ubc-21
ORF Names: C06E2.3
OrganismCaenorhabditis elegans [Complete proteome]
Taxonomic identifier6239 [NCBI]
Taxonomic lineageEukaryotaMetazoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis

Protein attributes

Sequence length229 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at transcript level.

General annotation (Comments)

Function

Catalyzes the covalent attachment of ubiquitin to other proteins By similarity.

Catalytic activity

ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.

Pathway

Protein modification; protein ubiquitination.

Sequence similarities

Belongs to the ubiquitin-conjugating enzyme family.

Contains 1 UBA domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 229229Probable ubiquitin-conjugating enzyme E2 21
PRO_0000082518

Regions

Domain187 – 22943UBA

Sites

Active site1211Glycyl thioester intermediate By similarity

Sequences

Sequence LengthMass (Da)Tools
P52484-1 [UniParc].

Last modified September 5, 2006. Version 2.
Checksum: 7FBE05784F66386C

FASTA22926,065
        10         20         30         40         50         60 
MSVSKLNKMQ FSDKMSNLAL ARVTRKCKEV ANASDITEAG IHVEIKENNL MDIKGFIKGP 

        70         80         90        100        110        120 
EGTPYAGGTF EIKVDIPEHY PFEPPKVTEI IFHIRAFEYI QAKFVTRIWH PNISSQTGTI 

       130        140        150        160        170        180 
CLDILKDKWT ASLTLRTVLL SLQAMLCSPE PSDPQDAVVA KQFINNYPMF TATAVYWTSY 

       190        200        210        220 
FANSKKDVEP DFNRKVGRLI EMGIRETEAI VYLSCNNWKL EQALQFIFD 

« Hide

References

[1]"Genome sequence of the nematode C. elegans: a platform for investigating biology."
The C. elegans sequencing consortium
Science 282:2012-2018(1998) [PubMed: 9851916] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Bristol N2.

Cross-references

Sequence databases

U39674 Genomic DNA. Translation: AAA80415.2.
PIRT15432.
RefSeqNP_509502.2.
UniGeneCel.25724

3D structure databases

HSSPHSSP built from PDB template 1FZY based on UniProtKB P21734.
ModBaseSearch...

Genome annotation databases

EnsemblC06E2.3. Caenorhabditis elegans. [Contig view]
GeneID182321.
KEGGcel:C06E2.3.

Organism-specific databases

WormBaseWBGene00006716. ubc-21.
WormPepC06E2.3. CE40013. [WorfDB]

Gene expression databases

ArrayExpressP52484.

Family and domain databases

InterProIPR015940. UBA/transl_elong_EF1B_N_euk.
IPR016135. UBQ-conjugat/RWD-like.
IPR000608. UBQ-conjugat_E2.
[Graphical view]
Gene3DG3DSA:3.10.110.10. UBQ-conjugat_E2. 1 hit.
PANTHERPTHR11621. UBQ-conjugat_E2. 1 hit.
PfamPF00179. UQ_con. 1 hit.
[Graphical view]
ProDomPD000461. UBQ_conjugat. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTSM00212. UBCc. 1 hit.
[Graphical view]
PROSITEPS50030. UBA. 1 hit.
PS00183. UBIQUITIN_CONJUGAT_1. 1 hit.
PS50127. UBIQUITIN_CONJUGAT_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other Resources

NextBio917164.

Entry information

Entry nameUBC21_CAEEL
AccessionPrimary (citable) accession number: P52484
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: September 5, 2006
Last modified: November 25, 2008
This is version 55 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectCaenorhabditis annotation project

Relevant documents

Caenorhabditis elegans

Caenorhabditis elegans: entries, gene names and cross-references to WormPep

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents