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P52424

- PUR5_VIGUN

UniProt

P52424 - PUR5_VIGUN

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Protein

Phosphoribosylformylglycinamidine cyclo-ligase, chloroplastic/mitochondrial

Gene

PUR5

Organism
Vigna unguiculata (Cowpea)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole.

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoribosylformylglycinamidine cyclo-ligase activity Source: UniProtKB-EC

GO - Biological processi

  1. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Purine biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BRENDAi6.3.3.1. 6657.
UniPathwayiUPA00074; UER00129.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoribosylformylglycinamidine cyclo-ligase, chloroplastic/mitochondrial (EC:6.3.3.1)
Alternative name(s):
AIR synthase
Short name:
AIRS
Phosphoribosyl-aminoimidazole synthetase
VUpur5
Gene namesi
Name:PUR5
OrganismiVigna unguiculata (Cowpea)
Taxonomic identifieri3917 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaePhaseoleaeVigna

Subcellular locationi

GO - Cellular componenti

  1. chloroplast Source: UniProtKB-KW
  2. mitochondrion Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Chloroplast, Mitochondrion, Plastid

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini? – 388Phosphoribosylformylglycinamidine cyclo-ligase, chloroplastic/mitochondrialPRO_0000029882
Transit peptidei1 – ?Chloroplast and mitochondrionSequence Analysis

Structurei

3D structure databases

ProteinModelPortaliP52424.
SMRiP52424. Positions 76-388.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the AIR synthase family.Curated

Keywords - Domaini

Transit peptide

Family and domain databases

Gene3Di3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPiMF_00741. AIRS.
InterProiIPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view]
PfamiPF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view]
SUPFAMiSSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsiTIGR00878. purM. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P52424-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSLSACAELS RCFAAAASAK PNSGKSNSTA ATSLVISSPI GHDGAVSSVS
60 70 80 90 100
RSRKTSRIVA EASQGLTYRD AGVDIDAGAE LVRRIAKMAP GIGGFGGLYP
110 120 130 140 150
LGDSYLVAGT DGVGTKLMLA FETGIHDTIG IDLVAMSVND IVTSGAKPLF
160 170 180 190 200
FLDYFATGRL DVDVAEKVVK GIVDGCKQSD CVLLGGETAE MPGLYKEGEY
210 220 230 240 250
DLSGCAVGIV KKDSVINGKN IVAGDVIIGL PSSGVHSNGF SLVRRVLAQS
260 270 280 290 300
GLSLKDQLPG SNITLAEALM APTVIYVKQV LDLISKGGVK GIAHITGGGF
310 320 330 340 350
TDNIPRVFPE GLGALIYDGS WEVPAVFRWL QEAGKIEDSE MRRTFNMGIG
360 370 380
MILVVSPEAA NRILENKGQA DKFYRIGEII SGNGVTFS
Length:388
Mass (Da):40,427
Last modified:October 1, 1996 - v1
Checksum:i15D0EF11127C9EE6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U30895 mRNA. Translation: AAC14578.1.
PIRiT10963.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U30895 mRNA. Translation: AAC14578.1 .
PIRi T10963.

3D structure databases

ProteinModelPortali P52424.
SMRi P52424. Positions 76-388.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Enzyme and pathway databases

UniPathwayi UPA00074 ; UER00129 .
BRENDAi 6.3.3.1. 6657.

Family and domain databases

Gene3Di 3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPi MF_00741. AIRS.
InterProi IPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view ]
Pfami PF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view ]
SUPFAMi SSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsi TIGR00878. purM. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "AIR synthetase in cowpea nodules: a single gene product targeted to two organelles?"
    Smith P.M.C., Mann A.J., Goggin D.E., Atkins C.A.
    Plant Mol. Biol. 36:811-820(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: cv. Vita 3.
    Tissue: Root nodule.

Entry informationi

Entry nameiPUR5_VIGUN
AccessioniPrimary (citable) accession number: P52424
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: November 26, 2014
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3