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P52409 (E13B_WHEAT) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucan endo-1,3-beta-glucosidase

EC=3.2.1.39
Alternative name(s):
(1->3)-beta-glucan endohydrolase
Short name=(1->3)-beta-glucanase
Beta-1,3-endoglucanase
Gene names
Name:GLC1
OrganismTriticum aestivum (Wheat) [Complete proteome]
Taxonomic identifier4565 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladePooideaeTriticeaeTriticum

Protein attributes

Sequence length461 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Is thought to be an important plant defense-related product against fungal pathogens.

Catalytic activity

Hydrolysis of (1->3)-beta-D-glucosidic linkages in (1->3)-beta-D-glucans.

Induction

Associated with aluminum toxicity.

Sequence similarities

Belongs to the glycosyl hydrolase 17 family.

Ontologies

Keywords
   Biological processPlant defense
   DomainSignal
   Molecular functionGlycosidase
Hydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processcarbohydrate metabolic process

Inferred from electronic annotation. Source: InterPro

defense response

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionglucan endo-1,3-beta-D-glucosidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2323 By similarity
Chain24 – 461438Glucan endo-1,3-beta-glucosidase
PRO_0000011881

Sites

Active site2651Nucleophile By similarity
Active site3281Proton donor By similarity

Sequences

Sequence LengthMass (Da)Tools
P52409 [UniParc].

Last modified October 1, 1996. Version 1.
Checksum: 7C45F10A026C87F9

FASTA46148,873
        10         20         30         40         50         60 
MPLLILLMLL AAGAAGAESA TPSLHIGVNY GANADNLPSP TSVATFLATK TTIDRVKLFD 

        70         80         90        100        110        120 
ANPTFISAFA GTPISLAVSL PNSALPALAD KATGLDAARS WIRANLSPYV PATNVTLLLA 

       130        140        150        160        170        180 
GNEILLSTDT NLILSLLPAM RRLAQALKAE GLTGVRVTTP HYLGILAPSD GIPSNASFRA 

       190        200        210        220        230        240 
GYNTKLFPAM LQFHRDTGSP FMVNPYPYFS YRPETLNYAL FRPNSGIYDP ATKLNYTSML 

       250        260        270        280        290        300 
DAQMDAIYTA MKKLGYGDVD IAVGEAGWPT QAEPGQIGVG VQEARDFNEG MIRVCSSGKG 

       310        320        330        340        350        360 
TPLMPNRTFE TYLFSLFDEN QKPGPIAERH FGLFNPDFTP VYDLGLLRDG ASVAPTPSPN 

       370        380        390        400        410        420 
PSPNPSPKPA PSGGGKWCVA KDGANGTDLQ NNINYACGFV DCKPIQSGGA CFSPNSLQAH 

       430        440        450        460 
ASYVMNAYYQ ANGHTDLACD FKGTGIVTSS DPSYGGCKYV S 

« Hide

References

[1]"Nucleotide sequence of cDNA for a 1,3-beta-glucanase associated with aluminum toxicity in wheat roots."
Cruz-Ortega R.M., Cushman J.C., Ownby J.D.
Plant Gene Register PGR95-073
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: cv. Victory.
Tissue: Root.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U30323 mRNA. Translation: AAA90953.1.
PIRT06268.
UniGeneTa.55395.

3D structure databases

ProteinModelPortalP52409.
SMRP52409. Positions 367-461.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

CAZyCBM43. Carbohydrate-Binding Module Family 43.
GH17. Glycoside Hydrolase Family 17.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

GrameneP52409.

Family and domain databases

Gene3D3.20.20.80. 1 hit.
InterProIPR000490. Glyco_hydro_17.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR012946. X8.
[Graphical view]
PfamPF00332. Glyco_hydro_17. 1 hit.
PF07983. X8. 1 hit.
[Graphical view]
SMARTSM00768. X8. 1 hit.
[Graphical view]
SUPFAMSSF51445. SSF51445. 1 hit.
PROSITEPS00587. GLYCOSYL_HYDROL_F17. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameE13B_WHEAT
AccessionPrimary (citable) accession number: P52409
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: June 11, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries