Reviewed, UniProtKB/Swiss-Prot P52409 (E13B_WHEAT)

Names and origin

Protein names

Recommended name:
    Glucan endo-1,3-beta-glucosidase
    EC=3.2.1.39
Alternative name(s):
    (1->3)-beta-glucan endohydrolase
      Short name=(1->3)-beta-glucanase
    Beta-1,3-endoglucanase

Gene names

Name:

GLC1

Organism

Triticum aestivum (Wheat)

Taxonomic identifier

4565 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Pooideae › Triticeae › Triticum

Protein attributes

Sequence length	461 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Is thought to be an important plant defense-related product against fungal pathogens.
Catalytic activity	Hydrolysis of (1->3)-beta-D-glucosidic linkages in (1->3)-beta-D-glucans.
Induction	Associated with aluminium toxicity.
Sequence similarities	Belongs to the glycosyl hydrolase 17 family.

Ontologies

Keywords
Biological process	Plant defense
Domain	Signal
Molecular function	Glycosidase Hydrolase
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro defense response Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	cation binding Inferred from electronic annotation. Source: InterPro glucan endo-1,3-beta-D-glucosidase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 23	23	By similarity
	Chain	24 – 461	438	Glucan endo-1,3-beta-glucosidase		PRO_0000011881
Sites
	Active site	265	1	Nucleophile By similarity
	Active site	328	1	Proton donor By similarity

Sequences

	Sequence		Length	Mass (Da)
	P52409-1 [UniParc]. Last modified October 1, 1996. Version 1. Checksum: 7C45F10A026C87F9	FASTA	461	48,873
	10 20 30 40 50 60 MPLLILLMLL AAGAAGAESA TPSLHIGVNY GANADNLPSP TSVATFLATK TTIDRVKLFD 70 80 90 100 110 120 ANPTFISAFA GTPISLAVSL PNSALPALAD KATGLDAARS WIRANLSPYV PATNVTLLLA 130 140 150 160 170 180 GNEILLSTDT NLILSLLPAM RRLAQALKAE GLTGVRVTTP HYLGILAPSD GIPSNASFRA 190 200 210 220 230 240 GYNTKLFPAM LQFHRDTGSP FMVNPYPYFS YRPETLNYAL FRPNSGIYDP ATKLNYTSML 250 260 270 280 290 300 DAQMDAIYTA MKKLGYGDVD IAVGEAGWPT QAEPGQIGVG VQEARDFNEG MIRVCSSGKG 310 320 330 340 350 360 TPLMPNRTFE TYLFSLFDEN QKPGPIAERH FGLFNPDFTP VYDLGLLRDG ASVAPTPSPN 370 380 390 400 410 420 PSPNPSPKPA PSGGGKWCVA KDGANGTDLQ NNINYACGFV DCKPIQSGGA CFSPNSLQAH 430 440 450 460 ASYVMNAYYQ ANGHTDLACD FKGTGIVTSS DPSYGGCKYV S

References

[1]	"Nucleotide sequence of cDNA for a 1,3-beta-glucanase associated with aluminum toxicity in wheat roots." Cruz-Ortega R.M., Cushman J.C., Ownby J.D. Plant Gene Register PGR95-073 Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: cv. Victory. Tissue: Root.

Cross-references

Sequence databases
EMBLGenBankDDBJ	U30323 mRNA. Translation: AAA90953.1.
PIR	T06268.
UniGene	Ta.55395
3D structure databases
HSSP	HSSP built from PDB template 1GHS based on UniProtKB P15737.
ModBase	Search...
Protein family/group databases
CAZy	CBM43. Carbohydrate-Binding Module Family 43. GH17. Glycoside Hydrolase Family 17.
Organism-specific databases
Gramene	P52409.
Enzyme and pathway databases
BRENDA	3.2.1.39. 253.
Family and domain databases
InterPro	IPR000490. Glyco_hydro_17. IPR013781. Glyco_hydro_sg_catalytic. IPR012946. X8. [Graphical view]
Gene3D	G3DSA:3.20.20.80. Glyco_hydro_cat. 1 hit.
Pfam	PF00332. Glyco_hydro_17. 1 hit. PF07983. X8. 1 hit. [Graphical view]
SMART	SM00768. X8. 1 hit. [Graphical view]
PROSITE	PS00587. GLYCOSYL_HYDROL_F17. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

E13B_WHEAT

Accession

Primary (citable) accession number: P52409

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1996
Last sequence update:	October 1, 1996
Last modified:	June 16, 2009
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)