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Protein

Endochitinase 2

Gene

CHTB2

Organism
Solanum tuberosum (Potato)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

Defense against chitin-containing fungal pathogens.

Catalytic activityi

Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidase, Hydrolase
Biological processCarbohydrate metabolism, Chitin degradation, Plant defense, Polysaccharide degradation
LigandChitin-binding

Protein family/group databases

CAZyiCBM18. Carbohydrate-Binding Module Family 18.
GH19. Glycoside Hydrolase Family 19.

Names & Taxonomyi

Protein namesi
Recommended name:
Endochitinase 2 (EC:3.2.1.14)
Gene namesi
Name:CHTB2
OrganismiSolanum tuberosum (Potato)
Taxonomic identifieri4113 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeSolanoideaeSolaneaeSolanum
Proteomesi
  • UP000011115 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Vacuole

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei‹1 – 18Sequence analysisAdd BLAST›18
ChainiPRO_000000532219 – 309Endochitinase 2Add BLAST291
PropeptideiPRO_0000005323310 – 316Removed in mature form, vacuolar targetingSequence analysis7

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi21 ↔ 36PROSITE-ProRule annotation
Disulfide bondi30 ↔ 42PROSITE-ProRule annotation
Disulfide bondi35 ↔ 49PROSITE-ProRule annotation
Disulfide bondi54 ↔ 58PROSITE-ProRule annotation
Disulfide bondi87 ↔ 150PROSITE-ProRule annotation
Disulfide bondi162 ↔ 170PROSITE-ProRule annotation
Disulfide bondi269 ↔ 301PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond

Expressioni

Developmental stagei

Highest levels in younger leaves or stems segments and in older ones. Leaves and stems of intermediate age show a decreased expression. Appreciable amounts are also found in old root segments, and carpels.

Inductioni

In response to infection, elicitor, ethylene, wounding.

Interactioni

Protein-protein interaction databases

STRINGi4113.PGSC0003DMT400069033.

Structurei

3D structure databases

ProteinModelPortaliP52404.
SMRiP52404.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini19 – 60Chitin-binding type-1PROSITE-ProRule annotationAdd BLAST42

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiKOG4742. Eukaryota.
COG3979. LUCA.
InParanoidiP52404.

Family and domain databases

CDDicd00325. chitinase_glyco_hydro_19. 1 hit.
Gene3Di3.30.60.10. 1 hit.
InterProiView protein in InterPro
IPR001002. Chitin-bd_1.
IPR018371. Chitin-binding_1_CS.
IPR036861. Endochitinase-like_sf.
IPR016283. Glyco_hydro_19.
IPR000726. Glyco_hydro_19_cat.
IPR023346. Lysozyme-like_dom_sf.
PfamiView protein in Pfam
PF00187. Chitin_bind_1. 1 hit.
PF00182. Glyco_hydro_19. 1 hit.
PIRSFiPIRSF001060. Endochitinase. 1 hit.
PRINTSiPR00451. CHITINBINDNG.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD000609. Chitin_bd_1. 1 hit.
SMARTiView protein in SMART
SM00270. ChtBD1. 1 hit.
SUPFAMiSSF53955. SSF53955. 1 hit.
SSF57016. SSF57016. 1 hit.
PROSITEiView protein in PROSITE
PS00026. CHIT_BIND_I_1. 1 hit.
PS50941. CHIT_BIND_I_2. 1 hit.
PS00773. CHITINASE_19_1. 1 hit.
PS00774. CHITINASE_19_2. 1 hit.

Sequencei

Sequence statusi: Fragment.

Sequence processingi: The displayed sequence is further processed into a mature form.

P52404-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
EFTTLFLLFS VLLLSASAEQ CGSQAGGALC ASGLCCSKFG WCGNTNDYCG
60 70 80 90 100
PGNCQSQCPG GSPGDLGGVI SNSMFDQMLN HRNDNACQGK GNFYSYNAFI
110 120 130 140 150
SAAGSFPGFG TTGDITARKR EIAAFFAQTS HETTGGWASA PDGPYAWGYC
160 170 180 190 200
FLREQGSPGD YCTPSNQWPC APGRKYFGRG PIQISHNYNY GPCGRAIGVD
210 220 230 240 250
LLNNPDLVAT DSIISFKSAI WFWMTPQSPK PSCHDVITGR WQPSGTDQAA
260 270 280 290 300
NRVPGFGVIT NIINGGLECG HGSDSRVQDR IGFYRRYCGI LGVSPGDNLD
310
CGNQRSFGNG LLVDTV
Length:316
Mass (Da):33,629
Last modified:October 1, 1996 - v1
Checksum:i81FB3DB3F222A0C6
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei11

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U02606 mRNA. Translation: AAA17408.1.
PIRiS65020.
UniGeneiStu.265.

Similar proteinsi

Entry informationi

Entry nameiCHI2_SOLTU
AccessioniPrimary (citable) accession number: P52404
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: November 22, 2017
This is version 102 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families