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P52401

- E132_SOLTU

UniProt

P52401 - E132_SOLTU

Protein

Glucan endo-1,3-beta-glucosidase, basic isoform 2

Gene

GLUB2

Organism
Solanum tuberosum (Potato)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 70 (01 Oct 2014)
      Sequence version 1 (01 Oct 1996)
      Previous versions | rss
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    Functioni

    Is thought to be an important plant defense-related product against fungal pathogens.

    Catalytic activityi

    Hydrolysis of (1->3)-beta-D-glucosidic linkages in (1->3)-beta-D-glucans.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei265 – 2651NucleophileBy similarity
    Active sitei321 – 3211Proton donorBy similarity

    GO - Molecular functioni

    1. glucan endo-1,3-beta-D-glucosidase activity Source: UniProtKB-EC

    GO - Biological processi

    1. carbohydrate metabolic process Source: InterPro
    2. defense response Source: UniProtKB-KW

    Keywords - Molecular functioni

    Glycosidase, Hydrolase

    Keywords - Biological processi

    Plant defense

    Protein family/group databases

    CAZyiGH17. Glycoside Hydrolase Family 17.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glucan endo-1,3-beta-glucosidase, basic isoform 2 (EC:3.2.1.39)
    Alternative name(s):
    (1->3)-beta-glucan endohydrolase
    Short name:
    (1->3)-beta-glucanase
    Beta-1,3-endoglucanase
    Gene namesi
    Name:GLUB2
    OrganismiSolanum tuberosum (Potato)
    Taxonomic identifieri4113 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeSolanoideaeSolaneaeSolanum
    ProteomesiUP000011115: Unplaced

    Subcellular locationi

    Vacuole By similarity

    GO - Cellular componenti

    1. vacuole Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Vacuole

    Pathology & Biotechi

    Protein family/group databases

    Allergomei2551. Sola t Glucanase.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2525Sequence AnalysisAdd
    BLAST
    Chaini26 – 340315Glucan endo-1,3-beta-glucosidase, basic isoform 2PRO_0000011862Add
    BLAST
    Propeptidei341 – 36323Removed in mature formBy similarityPRO_0000011863Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei26 – 261Pyrrolidone carboxylic acidCurated
    Glycosylationi353 – 3531N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein, Pyrrolidone carboxylic acid

    Expressioni

    Tissue specificityi

    High levels in leaves. Appreciable amounts in stems, roots, and sepals. Tubers, root tips, and all other flower organs contain very low levels of enzyme.

    Developmental stagei

    Highest levels in old segments of leaves, stems and roots.

    Inductioni

    In leaves, in response to infection, elicitor, ethylene, or wounding.

    Structurei

    3D structure databases

    ProteinModelPortaliP52401.
    SMRiP52401. Positions 27-339.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glycosyl hydrolase 17 family.Curated

    Keywords - Domaini

    Signal

    Family and domain databases

    Gene3Di3.20.20.80. 1 hit.
    InterProiIPR000490. Glyco_hydro_17.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view]
    PfamiPF00332. Glyco_hydro_17. 1 hit.
    [Graphical view]
    SUPFAMiSSF51445. SSF51445. 1 hit.
    PROSITEiPS00587. GLYCOSYL_HYDROL_F17. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P52401-1 [UniParc]FASTAAdd to Basket

    « Hide

    MATSQIAVIV LLGLLVATNI HITEAQLGVC YGMMGNNLPS HSEVIQLYKS    50
    RNIGRLRLYD PNQGALNALR GSNIEVILGL PNVDVKHIAS GMEHARWWVQ 100
    KNVKDFWPDV KIKYIAVGNE ISPVTGTSSL TSFQVPALVN IYKAVGEAGL 150
    GNDIKVSTSV DMTLIGNSYP PSQGSFRNDV RWFTDPIVGF LRDTRAPLLV 200
    NIYPYFSYSG NPGQISLPYA LFTAPNVVVQ DGSRQYRNLF DAMLDSVYAA 250
    MERTGGGSVG IVVSECGWPS AGAFGATQDN AATYLRNLIQ HAKEGSPRKP 300
    GPIETYIFAM FDENNKNPEL EKHFGLFSPN KQPKYNLNFG VSERVWDISA 350
    ETNSTASSLI SEM 363
    Length:363
    Mass (Da):39,759
    Last modified:October 1, 1996 - v1
    Checksum:i201A1A6A50C30DCC
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U01901 mRNA. Translation: AAA18928.1.
    PIRiS43318.
    RefSeqiNP_001274869.1. NM_001287940.1.
    UniGeneiStu.256.

    Genome annotation databases

    GeneIDi102577444.
    KEGGisot:102577444.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U01901 mRNA. Translation: AAA18928.1 .
    PIRi S43318.
    RefSeqi NP_001274869.1. NM_001287940.1.
    UniGenei Stu.256.

    3D structure databases

    ProteinModelPortali P52401.
    SMRi P52401. Positions 27-339.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    Allergomei 2551. Sola t Glucanase.
    CAZyi GH17. Glycoside Hydrolase Family 17.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 102577444.
    KEGGi sot:102577444.

    Family and domain databases

    Gene3Di 3.20.20.80. 1 hit.
    InterProi IPR000490. Glyco_hydro_17.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view ]
    Pfami PF00332. Glyco_hydro_17. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51445. SSF51445. 1 hit.
    PROSITEi PS00587. GLYCOSYL_HYDROL_F17. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Primary structure and expression of mRNAs encoding basic chitinase and 1,3-beta-glucanase in potato."
      Beerhues L., Kombrink E.
      Plant Mol. Biol. 24:353-367(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Strain: cv. Datura.
      Tissue: Leaf.

    Entry informationi

    Entry nameiE132_SOLTU
    AccessioniPrimary (citable) accession number: P52401
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 1, 1996
    Last sequence update: October 1, 1996
    Last modified: October 1, 2014
    This is version 70 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3