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Protein

Glucan endo-1,3-beta-glucosidase, basic isoform 2

Gene

GLUB2

Organism
Solanum tuberosum (Potato)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

Is thought to be an important plant defense-related product against fungal pathogens.

Catalytic activityi

Hydrolysis of (1->3)-beta-D-glucosidic linkages in (1->3)-beta-D-glucans.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei265NucleophileBy similarity1
Active sitei321Proton donorBy similarity1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Keywords - Biological processi

Plant defense

Protein family/group databases

CAZyiGH17. Glycoside Hydrolase Family 17.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucan endo-1,3-beta-glucosidase, basic isoform 2 (EC:3.2.1.39)
Alternative name(s):
(1->3)-beta-glucan endohydrolase
Short name:
(1->3)-beta-glucanase
Beta-1,3-endoglucanase
Gene namesi
Name:GLUB2
OrganismiSolanum tuberosum (Potato)
Taxonomic identifieri4113 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeSolanoideaeSolaneaeSolanum
Proteomesi
  • UP000011115 Componenti: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Vacuole

Pathology & Biotechi

Protein family/group databases

Allergomei2551. Sola t Glucanase.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25Sequence analysisAdd BLAST25
ChainiPRO_000001186226 – 340Glucan endo-1,3-beta-glucosidase, basic isoform 2Add BLAST315
PropeptideiPRO_0000011863341 – 363Removed in mature formBy similarityAdd BLAST23

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei26Pyrrolidone carboxylic acidCurated1
Glycosylationi353N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Glycoprotein, Pyrrolidone carboxylic acid

Proteomic databases

PRIDEiP52401.

Expressioni

Tissue specificityi

High levels in leaves. Appreciable amounts in stems, roots, and sepals. Tubers, root tips, and all other flower organs contain very low levels of enzyme.

Developmental stagei

Highest levels in old segments of leaves, stems and roots.

Inductioni

In leaves, in response to infection, elicitor, ethylene, or wounding.

Structurei

3D structure databases

ProteinModelPortaliP52401.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 17 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410IH05. Eukaryota.
ENOG410YAHP. LUCA.
InParanoidiP52401.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR000490. Glyco_hydro_17.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF00332. Glyco_hydro_17. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.
PROSITEiPS00587. GLYCOSYL_HYDROL_F17. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P52401-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATSQIAVIV LLGLLVATNI HITEAQLGVC YGMMGNNLPS HSEVIQLYKS
60 70 80 90 100
RNIGRLRLYD PNQGALNALR GSNIEVILGL PNVDVKHIAS GMEHARWWVQ
110 120 130 140 150
KNVKDFWPDV KIKYIAVGNE ISPVTGTSSL TSFQVPALVN IYKAVGEAGL
160 170 180 190 200
GNDIKVSTSV DMTLIGNSYP PSQGSFRNDV RWFTDPIVGF LRDTRAPLLV
210 220 230 240 250
NIYPYFSYSG NPGQISLPYA LFTAPNVVVQ DGSRQYRNLF DAMLDSVYAA
260 270 280 290 300
MERTGGGSVG IVVSECGWPS AGAFGATQDN AATYLRNLIQ HAKEGSPRKP
310 320 330 340 350
GPIETYIFAM FDENNKNPEL EKHFGLFSPN KQPKYNLNFG VSERVWDISA
360
ETNSTASSLI SEM
Length:363
Mass (Da):39,759
Last modified:October 1, 1996 - v1
Checksum:i201A1A6A50C30DCC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U01901 mRNA. Translation: AAA18928.1.
PIRiS43318.
RefSeqiNP_001274869.1. NM_001287940.1.
UniGeneiStu.256.

Genome annotation databases

GeneIDi102577444.
KEGGisot:102577444.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U01901 mRNA. Translation: AAA18928.1.
PIRiS43318.
RefSeqiNP_001274869.1. NM_001287940.1.
UniGeneiStu.256.

3D structure databases

ProteinModelPortaliP52401.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

Allergomei2551. Sola t Glucanase.
CAZyiGH17. Glycoside Hydrolase Family 17.

Proteomic databases

PRIDEiP52401.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi102577444.
KEGGisot:102577444.

Phylogenomic databases

eggNOGiENOG410IH05. Eukaryota.
ENOG410YAHP. LUCA.
InParanoidiP52401.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR000490. Glyco_hydro_17.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF00332. Glyco_hydro_17. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.
PROSITEiPS00587. GLYCOSYL_HYDROL_F17. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiE132_SOLTU
AccessioniPrimary (citable) accession number: P52401
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: October 5, 2016
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.