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P52311

- MTX2_XANOR

UniProt

P52311 - MTX2_XANOR

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Protein

Modification methylase XorII

Gene
xorIIM, XOO0607
Organism
Xanthomonas oryzae pv. oryzae (strain KACC10331 / KXO85)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

This methylase recognizes the double-stranded sequence CGATCG, causes specific methylation on C-? on both strands and protects the DNA from cleavage by the XorII endonuclease.

Catalytic activityi

S-adenosyl-L-methionine + DNA = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei83 – 831 By similarity

GO - Molecular functioni

  1. DNA (cytosine-5-)-methyltransferase activity Source: UniProtKB-EC
  2. DNA binding Source: InterPro

GO - Biological processi

  1. DNA restriction-modification system Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

Restriction system

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciXORY291331:GJBV-552-MONOMER.

Protein family/group databases

REBASEi3534. M.XorII.

Names & Taxonomyi

Protein namesi
Recommended name:
Modification methylase XorII (EC:2.1.1.37)
Short name:
M.XorII
Alternative name(s):
Cytosine-specific methyltransferase XorII
Gene namesi
Name:xorIIM
Ordered Locus Names:XOO0607
OrganismiXanthomonas oryzae pv. oryzae (strain KACC10331 / KXO85)
Taxonomic identifieri291331 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas
ProteomesiUP000006735: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 424424Modification methylase XorIIPRO_0000087910Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi291331.XOO0607.

Structurei

3D structure databases

ProteinModelPortaliP52311.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini4 – 367364SAM-dependent MTase C5-typeAdd
BLAST

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0270.
HOGENOMiHOG000225505.
KOiK00558.
OrthoDBiEOG6JQH0N.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
InterProiIPR018117. C5_DNA_meth_AS.
IPR001525. C5_MeTfrase.
IPR029063. SAM-dependent_MTases-like.
[Graphical view]
PANTHERiPTHR10629. PTHR10629. 1 hit.
PfamiPF00145. DNA_methylase. 1 hit.
[Graphical view]
PRINTSiPR00105. C5METTRFRASE.
SUPFAMiSSF53335. SSF53335. 2 hits.
TIGRFAMsiTIGR00675. dcm. 1 hit.
PROSITEiPS00094. C5_MTASE_1. 1 hit.
PS00095. C5_MTASE_2. 1 hit.
PS51679. SAM_MT_C5. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P52311-1 [UniParc]FASTAAdd to Basket

« Hide

MTRPIGIDLF AGAGGLSLGF EQAGFDLVAA VDIDPIHCAA HKFNFPKCAT    50
VCKSVVDVTG DELRRIAGIG KRDIDIVIGG APCQGFSLIG KRALDDSRNQ 100
LVHHYVRVVM ELKPKYFVFE NVKGLTVGKH RQFLKEVIEA FQNGGYDVVT 150
DYRVLNAADY GVPQDRRRLI LMGARKGLPL PAYPEPTGRT TVGDAIGDIP 200
DAESFPELWE RDWVKAKYGK PSTYAAYLRG KKDDPTDFGY RRQFDPMLLT 250
GSLLTDHTEL SRQRFAAIAP DDVEPVSRFK KLALNGICNT LRAGTASDRG 300
AFTSPRPIHP TVPRVITVRE AARLHSYPDW FRFHATKWHG FRQIGNSVPP 350
LLARAVGGQI MKALRKKPEK PSEMLALGDQ SLIGISMTDA AAMFGVSSTV 400
IARRSRPVDR PAPRRHEERE LVTA 424
Length:424
Mass (Da):46,900
Last modified:March 29, 2005 - v2
Checksum:iEBC3FD08DBACADEC
GO

Sequence cautioni

The sequence AAW73861.1 differs from that shown. Reason: Erroneous initiation.

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti60 – 612GD → RS in AAA50432. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U06424 Genomic DNA. Translation: AAA50432.1.
AE013598 Genomic DNA. Translation: AAW73861.1. Different initiation.
PIRiS46293.
RefSeqiYP_199246.1. NC_006834.1.

Genome annotation databases

EnsemblBacteriaiAAW73861; AAW73861; XOO0607.
GeneIDi3264300.
KEGGixoo:XOO0607.
PATRICi24100062. VBIXanOry111333_0681.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U06424 Genomic DNA. Translation: AAA50432.1 .
AE013598 Genomic DNA. Translation: AAW73861.1 . Different initiation.
PIRi S46293.
RefSeqi YP_199246.1. NC_006834.1.

3D structure databases

ProteinModelPortali P52311.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 291331.XOO0607.

Protein family/group databases

REBASEi 3534. M.XorII.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAW73861 ; AAW73861 ; XOO0607 .
GeneIDi 3264300.
KEGGi xoo:XOO0607.
PATRICi 24100062. VBIXanOry111333_0681.

Phylogenomic databases

eggNOGi COG0270.
HOGENOMi HOG000225505.
KOi K00558.
OrthoDBi EOG6JQH0N.

Enzyme and pathway databases

BioCyci XORY291331:GJBV-552-MONOMER.

Family and domain databases

Gene3Di 3.40.50.150. 1 hit.
InterProi IPR018117. C5_DNA_meth_AS.
IPR001525. C5_MeTfrase.
IPR029063. SAM-dependent_MTases-like.
[Graphical view ]
PANTHERi PTHR10629. PTHR10629. 1 hit.
Pfami PF00145. DNA_methylase. 1 hit.
[Graphical view ]
PRINTSi PR00105. C5METTRFRASE.
SUPFAMi SSF53335. SSF53335. 2 hits.
TIGRFAMsi TIGR00675. dcm. 1 hit.
PROSITEi PS00094. C5_MTASE_1. 1 hit.
PS00095. C5_MTASE_2. 1 hit.
PS51679. SAM_MT_C5. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Identification of the XorII methyltransferase gene and a vsr homolog from Xanthomonas oryzae pv. oryzae."
    Choi S.H., Leach J.E.
    Mol. Gen. Genet. 244:383-390(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: JW89011.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: KACC10331 / KXO85.

Entry informationi

Entry nameiMTX2_XANOR
AccessioniPrimary (citable) accession number: P52311
Secondary accession number(s): Q5H5A9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: March 29, 2005
Last modified: June 11, 2014
This is version 84 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Restriction enzymes and methylases
    Classification of restriction enzymes and methylases and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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