Reviewed,
UniProtKB/Swiss-Prot P52290 (PPAD_YEAST)
Last modified
October 13, 2009.
Version 72.
History...
Clusters with 100%,
90%,
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Probable acid phosphatase DIA3 EC=3.1.3.2 Alternative name(s): Digs into agar protein 3 | ||||||
| Gene names |
| ||||||
| Organism | Saccharomyces cerevisiae (Baker's yeast) [Complete proteome] | ||||||
| Taxonomic identifier | 4932 [NCBI] | ||||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces |
Protein attributes
| Sequence length | 468 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is further processed into a mature form. |
| Protein existence | Evidence at transcript level. |
General annotation (Comments)
| Catalytic activity | A phosphate monoester + H2O = an alcohol + phosphate. |
| Sequence similarities | Belongs to the histidine acid phosphatase family. |
Ontologies
| Keywords | |
|---|---|
| Domain | Signal |
| Molecular function | Hydrolase |
| PTM | Glycoprotein |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | invasive growth in response to glucose limitation Inferred from genetic interaction. Source: SGD pseudohyphal growthInferred from mutant phenotype. Source: SGD |
| Cellular component | fungal-type cell wall Inferred from direct assay. Source: SGD |
| Molecular function | acid phosphatase activity Inferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Signal peptide | 1 – 20 | 20 | By similarity | ||||||
| Chain | 21 – 468 | 448 | Probable acid phosphatase DIA3 | PRO_0000023958 | |||||
Sites | |||||||||
| Active site | 76 | 1 | Nucleophile By similarity | ||||||
| Active site | 339 | 1 | Proton donor By similarity | ||||||
Amino acid modifications | |||||||||
| Glycosylation | 98 | 1 | N-linked (GlcNAc...) Potential | ||||||
| Glycosylation | 163 | 1 | N-linked (GlcNAc...) Potential | ||||||
| Glycosylation | 193 | 1 | N-linked (GlcNAc...) Potential | ||||||
| Glycosylation | 202 | 1 | N-linked (GlcNAc...) Potential | ||||||
| Glycosylation | 238 | 1 | N-linked (GlcNAc...) Potential | ||||||
| Glycosylation | 251 | 1 | N-linked (GlcNAc...) Potential | ||||||
| Glycosylation | 316 | 1 | N-linked (GlcNAc...) Potential | ||||||
| Glycosylation | 357 | 1 | N-linked (GlcNAc...) Potential | ||||||
| Glycosylation | 391 | 1 | N-linked (GlcNAc...) Potential | ||||||
| Glycosylation | 457 | 1 | N-linked (GlcNAc...) Potential | ||||||
| Glycosylation | 462 | 1 | N-linked (GlcNAc...) Potential | ||||||
Sequences
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References
| [1] | "The nucleotide sequence of Saccharomyces cerevisiae chromosome IV." Jacq C., Alt-Moerbe J., Andre B., Arnold W., Bahr A., Ballesta J.P.G., Bargues M., Baron L., Becker A., Biteau N., Bloecker H., Blugeon C., Boskovic J., Brandt P., Brueckner M., Buitrago M.J., Coster F., Delaveau T.  Zaccaria P.Nature 387:75-78(1997) [PubMed: 9169867] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204508 / S288c. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| Z48432 Genomic DNA. Translation: CAA88335.1. Z74072 Genomic DNA. Translation: CAA98583.1. | |
| PIR | S52495. |
| RefSeq | NP_010260.1. |
3D structure databases | |
| HSSP | HSSP built from PDB template 1QFX based on UniProtKB P34755. |
| ModBase | Search... |
Protein-protein interaction databases | |
| DIP | DIP:5014N. |
| IntAct | P52290. 2 interactions. |
| STRING | P52290. |
Genome annotation databases | |
| Ensembl | YDL024C; YDL024C; YDL024C; Saccharomyces cerevisiae. [Genome view] |
| GeneID | 851537. |
| GenomeReviews | Gene locus YDL024C in contig Z71256_GR. |
| KEGG | sce:YDL024C. |
| NMPDR | fig|4932.3.peg.1001. |
Organism-specific databases | |
| CYGD | YDL024c. |
| SGD | S000002182. DIA3. |
Phylogenomic databases | |
| HOGENOM | P52290. |
Enzyme and pathway databases | |
| BRENDA | 3.1.3.2. 250. |
Gene expression databases | |
| ArrayExpress | P52290. |
| Genevestigator | P52290. |
| GermOnline | YDL024C. Saccharomyces cerevisiae. |
Family and domain databases | |
| InterPro | IPR000560. Histidine_acid_Pase. IPR016274. Histidine_acid_Pase_euk. [Graphical view] |
| Pfam | PF00328. Acid_phosphat_A. 1 hit. [Graphical view] |
| PIRSF | PIRSF000894. Acid_phosphatase. 1 hit. |
| PROSITE | PS00616. HIS_ACID_PHOSPHAT_1. 1 hit. PS00778. HIS_ACID_PHOSPHAT_2. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Other Resources | |
| NextBio | 968938. |
Entry information
| Entry name | PPAD_YEAST | ||||||||
| Accession | Primary (citable) accession number: P52290 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | FPAP (Fungal Proteome Annotation Project) | ||||||||
Relevant documents
| SIMILARITY comments Index of protein domains and families |
| Yeast Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD |
