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Protein

Probable acid phosphatase DIA3

Gene

DIA3

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

A phosphate monoester + H2O = an alcohol + phosphate.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei76NucleophileBy similarity1
Active sitei339Proton donorBy similarity1

GO - Molecular functioni

  • acid phosphatase activity Source: SGD

GO - Biological processi

  • invasive growth in response to glucose limitation Source: SGD
  • pseudohyphal growth Source: SGD

Keywordsi

Molecular functionHydrolase

Enzyme and pathway databases

BioCyciYEAST:G3O-29451-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Probable acid phosphatase DIA3 (EC:3.1.3.2)
Alternative name(s):
Digs into agar protein 3
Gene namesi
Name:DIA3
Ordered Locus Names:YDL024C
ORF Names:D2815
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome IV

Organism-specific databases

EuPathDBiFungiDB:YDL024C
SGDiS000002182 DIA3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20By similarityAdd BLAST20
ChainiPRO_000002395821 – 468Probable acid phosphatase DIA3Add BLAST448

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi98N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi163N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi193N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi202N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi238N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi251N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi316N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi357N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi391N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi457N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi462N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiP52290
PRIDEiP52290

Interactioni

Protein-protein interaction databases

BioGridi32031, 27 interactors
DIPiDIP-5014N
IntActiP52290, 2 interactors
STRINGi4932.YDL024C

Structurei

3D structure databases

ProteinModelPortaliP52290
SMRiP52290
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the histidine acid phosphatase family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

GeneTreeiENSGT00510000050349
HOGENOMiHOG000189191
InParanoidiP52290
KOiK01078
OMAiFLWCAFE
OrthoDBiEOG092C2L5B

Family and domain databases

CDDicd07061 HP_HAP_like, 1 hit
Gene3Di3.40.50.1240, 1 hit
InterProiView protein in InterPro
IPR033379 Acid_Pase_AS
IPR000560 His_Pase_clade-2
IPR029033 His_PPase_superfam
IPR016274 Histidine_acid_Pase_euk
PfamiView protein in Pfam
PF00328 His_Phos_2, 1 hit
PIRSFiPIRSF000894 Acid_phosphatase, 1 hit
SUPFAMiSSF53254 SSF53254, 1 hit
PROSITEiView protein in PROSITE
PS00616 HIS_ACID_PHOSPHAT_1, 1 hit
PS00778 HIS_ACID_PHOSPHAT_2, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P52290-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVKPVIFAIC LGVLLSKALS IPLRSFADIE LIGSQKSLFP FLGGSAPYFS
60 70 80 90 100
FPANYGIPTD IPEGCRLTQV QMIGRHGERY PTRSEAKDIF EVWYKISNYT
110 120 130 140 150
GKYEGSLSFL NNGYEFFIPD ESLLEMETTL QNSIDVLNPY TGEMNAKRHA
160 170 180 190 200
REFLAKYGKL MENCTNFPIF TTNSKRIYDT AQYFAEALGD GFNISLQTLS
210 220 230 240 250
ENSSSGANTL AAKSSCPNWN SNANNDILMS YSRDYLENIS DRLNDENKGL
260 270 280 290 300
NLSRKDAAAL FSWCAFELNA KGYSNICDIF SAAELIHYSY ETDLTSFYQN
310 320 330 340 350
GPGYKLIKSI GANLFNATVK LIRQSAHLDQ KVWLSFTHDT DILNYLTTAG
360 370 380 390 400
LIDDTRNLTT NHVPFRDHSY HRSWYIPQGA RVYTEKFQCS NDSYVRYVVN
410 420 430 440 450
DAVVPIESCS SGPGFSCEEG TFYEYAKDRL RGVSFYEDCD VSKVSKEKEL
460
TFYWDWNTTR YNASLVNQ
Length:468
Mass (Da):53,076
Last modified:October 1, 1996 - v1
Checksum:i1F07FF374DDF162C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z48432 Genomic DNA Translation: CAA88335.1
Z74072 Genomic DNA Translation: CAA98583.1
BK006938 Genomic DNA Translation: DAA11827.1
PIRiS52495
RefSeqiNP_010260.1, NM_001180083.1

Genome annotation databases

EnsemblFungiiYDL024C; YDL024C; YDL024C
GeneIDi851537
KEGGisce:YDL024C

Similar proteinsi

Entry informationi

Entry nameiPPAD_YEAST
AccessioniPrimary (citable) accession number: P52290
Secondary accession number(s): D6VRW7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: May 23, 2018
This is version 133 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome IV
    Yeast (Saccharomyces cerevisiae) chromosome IV: entries and gene names

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