Skip Header

Contribute Send feedback
Read comments (?) or add your own

P52290 (PPAD_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 90. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable acid phosphatase DIA3
EC=3.1.3.2
Alternative name(s):
Digs into agar protein 3
Gene names
Name:DIA3
Ordered Locus Names:YDL024C
ORF Names:D2815
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length468 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

A phosphate monoester + H2O = an alcohol + phosphate.

Sequence similarities

Belongs to the histidine acid phosphatase family.

Ontologies

Keywords
   DomainSignal
   Molecular functionHydrolase
   PTMGlycoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processinvasive growth in response to glucose limitation

Inferred from genetic interaction. Source: SGD

pseudohyphal growth

Inferred from mutant phenotype. Source: SGD

   Cellular componentfungal-type cell wall

Inferred from direct assay. Source: SGD

   Molecular functionacid phosphatase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2020 By similarity
Chain21 – 468448Probable acid phosphatase DIA3
PRO_0000023958

Sites

Active site761Nucleophile By similarity
Active site3391Proton donor By similarity

Amino acid modifications

Glycosylation981N-linked (GlcNAc...) Potential
Glycosylation1631N-linked (GlcNAc...) Potential
Glycosylation1931N-linked (GlcNAc...) Potential
Glycosylation2021N-linked (GlcNAc...) Potential
Glycosylation2381N-linked (GlcNAc...) Potential
Glycosylation2511N-linked (GlcNAc...) Potential
Glycosylation3161N-linked (GlcNAc...) Potential
Glycosylation3571N-linked (GlcNAc...) Potential
Glycosylation3911N-linked (GlcNAc...) Potential
Glycosylation4571N-linked (GlcNAc...) Potential
Glycosylation4621N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
P52290 [UniParc].

Last modified October 1, 1996. Version 1.
Checksum: 1F07FF374DDF162C

FASTA46853,076
        10         20         30         40         50         60 
MVKPVIFAIC LGVLLSKALS IPLRSFADIE LIGSQKSLFP FLGGSAPYFS FPANYGIPTD 

        70         80         90        100        110        120 
IPEGCRLTQV QMIGRHGERY PTRSEAKDIF EVWYKISNYT GKYEGSLSFL NNGYEFFIPD 

       130        140        150        160        170        180 
ESLLEMETTL QNSIDVLNPY TGEMNAKRHA REFLAKYGKL MENCTNFPIF TTNSKRIYDT 

       190        200        210        220        230        240 
AQYFAEALGD GFNISLQTLS ENSSSGANTL AAKSSCPNWN SNANNDILMS YSRDYLENIS 

       250        260        270        280        290        300 
DRLNDENKGL NLSRKDAAAL FSWCAFELNA KGYSNICDIF SAAELIHYSY ETDLTSFYQN 

       310        320        330        340        350        360 
GPGYKLIKSI GANLFNATVK LIRQSAHLDQ KVWLSFTHDT DILNYLTTAG LIDDTRNLTT 

       370        380        390        400        410        420 
NHVPFRDHSY HRSWYIPQGA RVYTEKFQCS NDSYVRYVVN DAVVPIESCS SGPGFSCEEG 

       430        440        450        460 
TFYEYAKDRL RGVSFYEDCD VSKVSKEKEL TFYWDWNTTR YNASLVNQ

« Hide

References

« Hide 'large scale' references
[1]"The nucleotide sequence of Saccharomyces cerevisiae chromosome IV."
Jacq C., Alt-Moerbe J., Andre B., Arnold W., Bahr A., Ballesta J.P.G., Bargues M., Baron L., Becker A., Biteau N., Bloecker H., Blugeon C., Boskovic J., Brandt P., Brueckner M., Buitrago M.J., Coster F., Delaveau T. expand/collapse author list , del Rey F., Dujon B., Eide L.G., Garcia-Cantalejo J.M., Goffeau A., Gomez-Peris A., Granotier C., Hanemann V., Hankeln T., Hoheisel J.D., Jaeger W., Jimenez A., Jonniaux J.-L., Kraemer C., Kuester H., Laamanen P., Legros Y., Louis E.J., Moeller-Rieker S., Monnet A., Moro M., Mueller-Auer S., Nussbaumer B., Paricio N., Paulin L., Perea J., Perez-Alonso M., Perez-Ortin J.E., Pohl T.M., Prydz H., Purnelle B., Rasmussen S.W., Remacha M.A., Revuelta J.L., Rieger M., Salom D., Saluz H.P., Saiz J.E., Saren A.-M., Schaefer M., Scharfe M., Schmidt E.R., Schneider C., Scholler P., Schwarz S., Soler-Mira A., Urrestarazu L.A., Verhasselt P., Vissers S., Voet M., Volckaert G., Wagner G., Wambutt R., Wedler E., Wedler H., Woelfl S., Harris D.E., Bowman S., Brown D., Churcher C.M., Connor R., Dedman K., Gentles S., Hamlin N., Hunt S., Jones L., McDonald S., Murphy L.D., Niblett D., Odell C., Oliver K., Rajandream M.A., Richards C., Shore L., Walsh S.V., Barrell B.G., Dietrich F.S., Mulligan J.T., Allen E., Araujo R., Aviles E., Berno A., Carpenter J., Chen E., Cherry J.M., Chung E., Duncan M., Hunicke-Smith S., Hyman R.W., Komp C., Lashkari D., Lew H., Lin D., Mosedale D., Nakahara K., Namath A., Oefner P., Oh C., Petel F.X., Roberts D., Schramm S., Schroeder M., Shogren T., Shroff N., Winant A., Yelton M.A., Botstein D., Davis R.W., Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Du Z., Favello A., Fulton L., Gattung S., Greco T., Hallsworth K., Hawkins J., Hillier L.W., Jier M., Johnson D., Johnston L., Kirsten J., Kucaba T., Langston Y., Latreille P., Le T., Mardis E., Menezes S., Miller N., Nhan M., Pauley A., Peluso D., Rifkin L., Riles L., Taich A., Trevaskis E., Vignati D., Wilcox L., Wohldman P., Vaudin M., Wilson R., Waterston R., Albermann K., Hani J., Heumann K., Kleine K., Mewes H.-W., Zollner A., Zaccaria P.
Nature 387:75-78(1997) [PubMed: 9169867] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		Z48432 Genomic DNA. Translation: CAA88335.1.
Z74072 Genomic DNA. Translation: CAA98583.1.
BK006938 Genomic DNA. Translation: DAA11827.1.
PIRS52495.
RefSeqNP_010260.1. NM_001180083.1.

3D structure databases

ProteinModelPortalP52290.
SMRP52290. Positions 33-468.
ModBaseSearch...

Protein-protein interaction databases

DIPDIP-5014N.
IntActP52290. 1 interaction.
MINTMINT-475083.
STRINGP52290.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYDL024C; YDL024C; YDL024C.
GeneID851537.
KEGGsce:YDL024C.
NMPDRfig|4932.3.peg.1001.

Organism-specific databases

CYGDYDL024c.
SGDS000002182. DIA3.

Phylogenomic databases

eggNOGfuNOG08329.
GeneTreeEFGT00050000003976.
HOGENOMHBG331692.
OrthoDBEOG42Z7ZR.

Gene expression databases

ArrayExpressP52290.
GenevestigatorP52290.
GermOnlineYDL024C. Saccharomyces cerevisiae.

Family and domain databases

InterProIPR000560. His_Pase_superF_clade-2.
IPR016274. Histidine_acid_Pase_euk.
[Graphical view]
KOK01078.
PfamPF00328. His_Phos_2. 1 hit.
[Graphical view]
PIRSFPIRSF000894. Acid_phosphatase. 1 hit.
PROSITEPS00616. HIS_ACID_PHOSPHAT_1. 1 hit.
PS00778. HIS_ACID_PHOSPHAT_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio968938.

Entry information

Entry namePPAD_YEAST
AccessionPrimary (citable) accession number: P52290
Secondary accession number(s): D6VRW7
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: December 14, 2011
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents