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P52290

- PPAD_YEAST

UniProt

P52290 - PPAD_YEAST

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Protein

Probable acid phosphatase DIA3

Gene

DIA3

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

A phosphate monoester + H2O = an alcohol + phosphate.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei76 – 761NucleophileBy similarity
Active sitei339 – 3391Proton donorBy similarity

GO - Molecular functioni

  1. acid phosphatase activity Source: SGD

GO - Biological processi

  1. dephosphorylation Source: GOC
  2. invasive growth in response to glucose limitation Source: SGD
  3. pseudohyphal growth Source: SGD
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciYEAST:G3O-29451-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable acid phosphatase DIA3 (EC:3.1.3.2)
Alternative name(s):
Digs into agar protein 3
Gene namesi
Name:DIA3
Ordered Locus Names:YDL024C
ORF Names:D2815
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome IV

Organism-specific databases

CYGDiYDL024c.
SGDiS000002182. DIA3.

Subcellular locationi

GO - Cellular componenti

  1. fungal-type cell wall Source: SGD
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2020By similarityAdd
BLAST
Chaini21 – 468448Probable acid phosphatase DIA3PRO_0000023958Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi98 – 981N-linked (GlcNAc...)Sequence Analysis
Glycosylationi163 – 1631N-linked (GlcNAc...)Sequence Analysis
Glycosylationi193 – 1931N-linked (GlcNAc...)Sequence Analysis
Glycosylationi202 – 2021N-linked (GlcNAc...)Sequence Analysis
Glycosylationi238 – 2381N-linked (GlcNAc...)Sequence Analysis
Glycosylationi251 – 2511N-linked (GlcNAc...)Sequence Analysis
Glycosylationi316 – 3161N-linked (GlcNAc...)Sequence Analysis
Glycosylationi357 – 3571N-linked (GlcNAc...)Sequence Analysis
Glycosylationi391 – 3911N-linked (GlcNAc...)Sequence Analysis
Glycosylationi457 – 4571N-linked (GlcNAc...)Sequence Analysis
Glycosylationi462 – 4621N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Expressioni

Gene expression databases

GenevestigatoriP52290.

Interactioni

Protein-protein interaction databases

BioGridi32031. 12 interactions.
DIPiDIP-5014N.
IntActiP52290. 1 interaction.
MINTiMINT-475083.
STRINGi4932.YDL024C.

Structurei

3D structure databases

ProteinModelPortaliP52290.
SMRiP52290. Positions 35-467.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the histidine acid phosphatase family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiNOG265642.
GeneTreeiENSGT00510000050349.
HOGENOMiHOG000189191.
InParanoidiP52290.
KOiK01078.
OMAiNICDIFS.
OrthoDBiEOG7TQV9N.

Family and domain databases

Gene3Di3.40.50.1240. 1 hit.
InterProiIPR000560. His_Pase_superF_clade-2.
IPR029033. His_PPase_superfam.
IPR016274. Histidine_acid_Pase_euk.
[Graphical view]
PfamiPF00328. His_Phos_2. 1 hit.
[Graphical view]
PIRSFiPIRSF000894. Acid_phosphatase. 1 hit.
SUPFAMiSSF53254. SSF53254. 1 hit.
PROSITEiPS00616. HIS_ACID_PHOSPHAT_1. 1 hit.
PS00778. HIS_ACID_PHOSPHAT_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P52290-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVKPVIFAIC LGVLLSKALS IPLRSFADIE LIGSQKSLFP FLGGSAPYFS
60 70 80 90 100
FPANYGIPTD IPEGCRLTQV QMIGRHGERY PTRSEAKDIF EVWYKISNYT
110 120 130 140 150
GKYEGSLSFL NNGYEFFIPD ESLLEMETTL QNSIDVLNPY TGEMNAKRHA
160 170 180 190 200
REFLAKYGKL MENCTNFPIF TTNSKRIYDT AQYFAEALGD GFNISLQTLS
210 220 230 240 250
ENSSSGANTL AAKSSCPNWN SNANNDILMS YSRDYLENIS DRLNDENKGL
260 270 280 290 300
NLSRKDAAAL FSWCAFELNA KGYSNICDIF SAAELIHYSY ETDLTSFYQN
310 320 330 340 350
GPGYKLIKSI GANLFNATVK LIRQSAHLDQ KVWLSFTHDT DILNYLTTAG
360 370 380 390 400
LIDDTRNLTT NHVPFRDHSY HRSWYIPQGA RVYTEKFQCS NDSYVRYVVN
410 420 430 440 450
DAVVPIESCS SGPGFSCEEG TFYEYAKDRL RGVSFYEDCD VSKVSKEKEL
460
TFYWDWNTTR YNASLVNQ
Length:468
Mass (Da):53,076
Last modified:October 1, 1996 - v1
Checksum:i1F07FF374DDF162C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z48432 Genomic DNA. Translation: CAA88335.1.
Z74072 Genomic DNA. Translation: CAA98583.1.
BK006938 Genomic DNA. Translation: DAA11827.1.
PIRiS52495.
RefSeqiNP_010260.1. NM_001180083.1.

Genome annotation databases

EnsemblFungiiYDL024C; YDL024C; YDL024C.
GeneIDi851537.
KEGGisce:YDL024C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z48432 Genomic DNA. Translation: CAA88335.1 .
Z74072 Genomic DNA. Translation: CAA98583.1 .
BK006938 Genomic DNA. Translation: DAA11827.1 .
PIRi S52495.
RefSeqi NP_010260.1. NM_001180083.1.

3D structure databases

ProteinModelPortali P52290.
SMRi P52290. Positions 35-467.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 32031. 12 interactions.
DIPi DIP-5014N.
IntActi P52290. 1 interaction.
MINTi MINT-475083.
STRINGi 4932.YDL024C.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YDL024C ; YDL024C ; YDL024C .
GeneIDi 851537.
KEGGi sce:YDL024C.

Organism-specific databases

CYGDi YDL024c.
SGDi S000002182. DIA3.

Phylogenomic databases

eggNOGi NOG265642.
GeneTreei ENSGT00510000050349.
HOGENOMi HOG000189191.
InParanoidi P52290.
KOi K01078.
OMAi NICDIFS.
OrthoDBi EOG7TQV9N.

Enzyme and pathway databases

BioCyci YEAST:G3O-29451-MONOMER.

Miscellaneous databases

NextBioi 968938.

Gene expression databases

Genevestigatori P52290.

Family and domain databases

Gene3Di 3.40.50.1240. 1 hit.
InterProi IPR000560. His_Pase_superF_clade-2.
IPR029033. His_PPase_superfam.
IPR016274. Histidine_acid_Pase_euk.
[Graphical view ]
Pfami PF00328. His_Phos_2. 1 hit.
[Graphical view ]
PIRSFi PIRSF000894. Acid_phosphatase. 1 hit.
SUPFAMi SSF53254. SSF53254. 1 hit.
PROSITEi PS00616. HIS_ACID_PHOSPHAT_1. 1 hit.
PS00778. HIS_ACID_PHOSPHAT_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The nucleotide sequence of Saccharomyces cerevisiae chromosome IV."
    Jacq C., Alt-Moerbe J., Andre B., Arnold W., Bahr A., Ballesta J.P.G., Bargues M., Baron L., Becker A., Biteau N., Bloecker H., Blugeon C., Boskovic J., Brandt P., Brueckner M., Buitrago M.J., Coster F., Delaveau T.
    , del Rey F., Dujon B., Eide L.G., Garcia-Cantalejo J.M., Goffeau A., Gomez-Peris A., Granotier C., Hanemann V., Hankeln T., Hoheisel J.D., Jaeger W., Jimenez A., Jonniaux J.-L., Kraemer C., Kuester H., Laamanen P., Legros Y., Louis E.J., Moeller-Rieker S., Monnet A., Moro M., Mueller-Auer S., Nussbaumer B., Paricio N., Paulin L., Perea J., Perez-Alonso M., Perez-Ortin J.E., Pohl T.M., Prydz H., Purnelle B., Rasmussen S.W., Remacha M.A., Revuelta J.L., Rieger M., Salom D., Saluz H.P., Saiz J.E., Saren A.-M., Schaefer M., Scharfe M., Schmidt E.R., Schneider C., Scholler P., Schwarz S., Soler-Mira A., Urrestarazu L.A., Verhasselt P., Vissers S., Voet M., Volckaert G., Wagner G., Wambutt R., Wedler E., Wedler H., Woelfl S., Harris D.E., Bowman S., Brown D., Churcher C.M., Connor R., Dedman K., Gentles S., Hamlin N., Hunt S., Jones L., McDonald S., Murphy L.D., Niblett D., Odell C., Oliver K., Rajandream M.A., Richards C., Shore L., Walsh S.V., Barrell B.G., Dietrich F.S., Mulligan J.T., Allen E., Araujo R., Aviles E., Berno A., Carpenter J., Chen E., Cherry J.M., Chung E., Duncan M., Hunicke-Smith S., Hyman R.W., Komp C., Lashkari D., Lew H., Lin D., Mosedale D., Nakahara K., Namath A., Oefner P., Oh C., Petel F.X., Roberts D., Schramm S., Schroeder M., Shogren T., Shroff N., Winant A., Yelton M.A., Botstein D., Davis R.W., Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Du Z., Favello A., Fulton L., Gattung S., Greco T., Hallsworth K., Hawkins J., Hillier L.W., Jier M., Johnson D., Johnston L., Kirsten J., Kucaba T., Langston Y., Latreille P., Le T., Mardis E., Menezes S., Miller N., Nhan M., Pauley A., Peluso D., Rifkin L., Riles L., Taich A., Trevaskis E., Vignati D., Wilcox L., Wohldman P., Vaudin M., Wilson R., Waterston R., Albermann K., Hani J., Heumann K., Kleine K., Mewes H.-W., Zollner A., Zaccaria P.
    Nature 387:75-78(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.

Entry informationi

Entry nameiPPAD_YEAST
AccessioniPrimary (citable) accession number: P52290
Secondary accession number(s): D6VRW7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: October 29, 2014
This is version 109 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome IV
    Yeast (Saccharomyces cerevisiae) chromosome IV: entries and gene names

External Data

Dasty 3