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Protein

Asparagine--tRNA ligase

Gene

asnS

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-asparagine + tRNA(Asn) = AMP + diphosphate + L-asparaginyl-tRNA(Asn).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Asparagine--tRNA ligaseUniRule annotation (EC:6.1.1.22UniRule annotation)
Alternative name(s):
Asparaginyl-tRNA synthetaseUniRule annotation
Short name:
AsnRSUniRule annotation
Gene namesi
Name:asnSUniRule annotation
Ordered Locus Names:sll0495
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis
ProteomesiUP000001425 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 462462Asparagine--tRNA ligasePRO_0000176468Add
BLAST

Proteomic databases

PaxDbiP52276.
PRIDEiP52276.

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

IntActiP52276. 1 interaction.
STRINGi1148.SYNGTS_2881.

Structurei

3D structure databases

ProteinModelPortaliP52276.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class-II aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0017.
HOGENOMiHOG000226033.
InParanoidiP52276.
OMAiAIHRFFH.
PhylomeDBiP52276.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
HAMAPiMF_00534. Asn_tRNA_synth.
InterProiIPR004364. aa-tRNA-synt_II.
IPR018150. aa-tRNA-synt_II-like.
IPR006195. aa-tRNA-synth_II.
IPR004522. Asn-tRNA-ligase.
IPR002312. Asp/Asn-tRNA-synth_IIb.
IPR012340. NA-bd_OB-fold.
IPR004365. NA-bd_OB_tRNA.
[Graphical view]
PANTHERiPTHR22594. PTHR22594. 1 hit.
PfamiPF00152. tRNA-synt_2. 1 hit.
PF01336. tRNA_anti-codon. 1 hit.
[Graphical view]
PRINTSiPR01042. TRNASYNTHASP.
SUPFAMiSSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00457. asnS. 1 hit.
PROSITEiPS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P52276-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKRRIIEVL RHGQADDQVM VQGWLRTKRT LKDFSFVEVN DGSSLANLQV
60 70 80 90 100
VLDGSLADYD RLLSQLQTGA ALVVEGKLAP SPGKGQRVEL KATKLELLGG
110 120 130 140 150
ADPGSYPLQK KRHSFEFLRT IGHLRPRTNT IGAVMRVRNA CATAIHQFFQ
160 170 180 190 200
ERGFLWVHTP IITASDCEGA GDLFKVTTLD LQRVPKNGEG IDYSQDFFGK
210 220 230 240 250
QAYLTVSGQL EAEVMALAFQ NVYTFGPTFR AENSNTSRHL AEFWMVEPEM
260 270 280 290 300
AFCDLEGDRQ WAEEFLKYIF KFVLEKCPED MEFFDQRIDN TVLATADNII
310 320 330 340 350
NNEFAWLTYS EAIKLLEKAD QKFEYPVAWG VDLQSEHERY LAETVFKRPT
360 370 380 390 400
IVTDYPKDIK AFYMRLNDDG KTVAAMDILA PKIGEIIGGS QREERLDILT
410 420 430 440 450
QRMQEQGVPE EDLWWYLDLR RYGSVPHAGF GLGFERIVQF MTGMANIRDV
460
IPFPRTPMNA EF
Length:462
Mass (Da):52,699
Last modified:January 31, 2002 - v2
Checksum:i6E177B9BC0F25D1F
GO

Sequence cautioni

The sequence BAA10844.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA. Translation: BAA10844.1. Different initiation.
PIRiS75997.
RefSeqiYP_007452649.1. NC_020286.1.

Genome annotation databases

EnsemblBacteriaiBAA10844; BAA10844; BAA10844.
PATRICi23843302. VBISynSp132158_3189.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA. Translation: BAA10844.1. Different initiation.
PIRiS75997.
RefSeqiYP_007452649.1. NC_020286.1.

3D structure databases

ProteinModelPortaliP52276.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP52276. 1 interaction.
STRINGi1148.SYNGTS_2881.

Proteomic databases

PaxDbiP52276.
PRIDEiP52276.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAA10844; BAA10844; BAA10844.
PATRICi23843302. VBISynSp132158_3189.

Phylogenomic databases

eggNOGiCOG0017.
HOGENOMiHOG000226033.
InParanoidiP52276.
OMAiAIHRFFH.
PhylomeDBiP52276.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
HAMAPiMF_00534. Asn_tRNA_synth.
InterProiIPR004364. aa-tRNA-synt_II.
IPR018150. aa-tRNA-synt_II-like.
IPR006195. aa-tRNA-synth_II.
IPR004522. Asn-tRNA-ligase.
IPR002312. Asp/Asn-tRNA-synth_IIb.
IPR012340. NA-bd_OB-fold.
IPR004365. NA-bd_OB_tRNA.
[Graphical view]
PANTHERiPTHR22594. PTHR22594. 1 hit.
PfamiPF00152. tRNA-synt_2. 1 hit.
PF01336. tRNA_anti-codon. 1 hit.
[Graphical view]
PRINTSiPR01042. TRNASYNTHASP.
SUPFAMiSSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00457. asnS. 1 hit.
PROSITEiPS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. I. Sequence features in the 1 Mb region from map positions 64% to 92% of the genome."
    Kaneko T., Tanaka A., Sato S., Kotani H., Sazuka T., Miyajima N., Sugiura M., Tabata S.
    DNA Res. 2:153-166(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 27184 / PCC 6803 / N-1.
  2. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
    Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.
    , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
    DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PCC 6803 / Kazusa.

Entry informationi

Entry nameiSYN_SYNY3
AccessioniPrimary (citable) accession number: P52276
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: January 31, 2002
Last modified: June 24, 2015
This is version 110 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families
  3. Synechocystis PCC 6803
    Synechocystis (strain PCC 6803): entries and gene names

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.