Reviewed,
UniProtKB/Swiss-Prot P52208 (6PGD_SYNY3)
Last modified
February 9, 2010.
Version 64.
History...
Clusters with 100%,
90%,
50% identity |
Documents (3) |
Third-party data |
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Names and origin
| Protein names | Recommended name: 6-phosphogluconate dehydrogenase, decarboxylating EC=1.1.1.44 | ||||
| Gene names |
| ||||
| Organism | Synechocystis sp. (strain PCC 6803) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 1148 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Cyanobacteria › Chroococcales › Synechocystis |
Protein attributes
| Sequence length | 482 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Catalytic activity | 6-phospho-D-gluconate + NADP+ = D-ribulose 5-phosphate + CO2 + NADPH. |
| Pathway | |
| Sequence similarities | Belongs to the 6-phosphogluconate dehydrogenase family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Gluconate utilization Pentose shunt |
| Ligand | NADP |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | D-gluconate metabolic process Inferred from electronic annotation. Source: UniProtKB-KW oxidation reductionInferred from electronic annotation. Source: UniProtKB-KW pentose-phosphate shuntInferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | NADP or NADPH binding Inferred from electronic annotation. Source: InterPro phosphogluconate dehydrogenase (decarboxylating) activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 482 | 482 | 6-phosphogluconate dehydrogenase, decarboxylating | PRO_0000090061 | |||
Sequences
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References
| [1] | "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. I. Sequence features in the 1 Mb region from map positions 64% to 92% of the genome." Kaneko T., Tanaka A., Sato S., Kotani H., Sazuka T., Miyajima N., Sugiura M., Tabata S. DNA Res. 2:153-166(1995) [PubMed: 8590279] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
| [2] | "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions." Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. Tabata S.DNA Res. 3:109-136(1996) [PubMed: 8905231] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | BA000022 Genomic DNA. Translation: BAA10105.1. |
| PIR | S76127. |
| RefSeq | NP_442035.1. |
3D structure databases | |
| SMR | P52208. Positions 8-482. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | P52208. |
Genome annotation databases | |
| GeneID | 952734. |
| GenomeReviews | Gene locus sll0329 in contig BA000022_GR. |
| KEGG | syn:sll0329. |
| NMPDR | fig|1148.1.peg.2136. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| eggNOG | COG0362. |
| HOGENOM | HBG286913. |
| OMA | GQKEAYD. |
| PhylomeDB | P52208. |
Enzyme and pathway databases | |
| BioCyc | SSP1148:SLL0329-MONOMER. |
Family and domain databases | |
| InterPro | IPR008927. 6-PGluconate_DH_C-like. IPR006183. 6-phosphogluconate_DH. IPR006114. 6PGDH_C. IPR006113. 6PGDH_decarbox. IPR006115. 6PGDH_NAD-bd. IPR006184. 6PGdom_BS. IPR013328. DH_multihelical. IPR012284. Fibritin/6PGD_C-extension. IPR016040. NAD(P)-bd_dom. [Graphical view] |
| Gene3D | G3DSA:1.20.5.320. Fibritin/6PGD_C-extension. 1 hit. G3DSA:3.40.50.720. NAD(P)-bd. 1 hit. G3DSA:1.10.1040.10. Opine_DH. 1 hit. |
| Pfam | PF00393. 6PGD. 1 hit. PF03446. NAD_binding_2. 1 hit. [Graphical view] |
| PRINTS | PR00076. 6PGDHDRGNASE. |
| TIGRFAMs | TIGR00873. gnd. 1 hit. |
| PROSITE | PS00461. 6PGD. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | 6PGD_SYNY3 | ||||||||
| Accession | Primary (citable) accession number: P52208 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |
| Synechocystis PCC 6803 Synechocystis (strain PCC 6803): entries and gene names |

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