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P52179

- MYOM1_HUMAN

UniProt

P52179 - MYOM1_HUMAN

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Protein

Myomesin-1

Gene

MYOM1

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli

Functioni

Major component of the vertebrate myofibrillar M band. Binds myosin, titin, and light meromyosin. This binding is dose dependent.

GO - Molecular functioni

  1. identical protein binding Source: IntAct
  2. protein homodimerization activity Source: UniProtKB
  3. structural constituent of muscle Source: ProtInc

GO - Biological processi

  1. muscle contraction Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

Muscle protein

Names & Taxonomyi

Protein namesi
Recommended name:
Myomesin-1
Alternative name(s):
190 kDa connectin-associated protein
190 kDa titin-associated protein
Myomesin family member 1
Gene namesi
Name:MYOM1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 18

Organism-specific databases

HGNCiHGNC:7613. MYOM1.

Subcellular locationi

CytoplasmmyofibrilsarcomereM line By similarity

GO - Cellular componenti

  1. M band Source: UniProtKB
  2. striated muscle myosin thick filament Source: ProtInc
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Thick filament

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA31418.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 16851685Myomesin-1PRO_0000072684Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi1160 ↔ 1210PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond

Proteomic databases

MaxQBiP52179.
PaxDbiP52179.
PRIDEiP52179.

PTM databases

PhosphoSiteiP52179.

Expressioni

Gene expression databases

BgeeiP52179.
CleanExiHS_MYOM1.
ExpressionAtlasiP52179. baseline and differential.
GenevestigatoriP52179.

Organism-specific databases

HPAiHPA014305.

Interactioni

Subunit structurei

Homodimer (By similarity). Interacts with TTN/titin (By similarity). Interacts with PNKD.By similarity1 Publication

Binary interactionsi

WithEntry#Exp.IntActNotes
itself4EBI-5353249,EBI-5353249
DYSFO759233EBI-5353249,EBI-2799016

Protein-protein interaction databases

DIPiDIP-59649N.
IntActiP52179. 6 interactions.
STRINGi9606.ENSP00000348821.

Structurei

Secondary structure

1
1685
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi1145 – 11484Combined sources
Beta strandi1154 – 11596Combined sources
Beta strandi1169 – 11735Combined sources
Beta strandi1184 – 11896Combined sources
Beta strandi1192 – 11998Combined sources
Helixi1202 – 12043Combined sources
Beta strandi1206 – 121510Combined sources
Beta strandi1220 – 12245Combined sources
Helixi1226 – 124015Combined sources
Beta strandi1248 – 12547Combined sources
Helixi1256 – 12583Combined sources
Beta strandi1260 – 12656Combined sources
Beta strandi1274 – 12796Combined sources
Beta strandi1282 – 12843Combined sources
Beta strandi1286 – 12894Combined sources
Beta strandi1291 – 12944Combined sources
Turni1296 – 12983Combined sources
Beta strandi1300 – 13067Combined sources
Helixi1310 – 13123Combined sources
Beta strandi1314 – 13229Combined sources
Beta strandi1325 – 13339Combined sources
Helixi1336 – 135520Combined sources
Beta strandi1357 – 136913Combined sources
Turni1370 – 13723Combined sources
Beta strandi1373 – 138210Combined sources
Beta strandi1388 – 13936Combined sources
Beta strandi1396 – 13983Combined sources
Beta strandi1407 – 14159Combined sources
Helixi1420 – 14223Combined sources
Beta strandi1424 – 14329Combined sources
Beta strandi1435 – 14439Combined sources
Helixi1446 – 146015Combined sources
Beta strandi1467 – 14704Combined sources
Beta strandi1472 – 148312Combined sources
Beta strandi1489 – 14946Combined sources
Beta strandi1503 – 15108Combined sources
Beta strandi1513 – 15208Combined sources
Helixi1523 – 15253Combined sources
Beta strandi1527 – 15348Combined sources
Beta strandi1539 – 15468Combined sources
Helixi1548 – 157023Combined sources
Beta strandi1573 – 15775Combined sources
Beta strandi1580 – 15856Combined sources
Beta strandi1590 – 15978Combined sources
Beta strandi1603 – 16086Combined sources
Beta strandi1611 – 16133Combined sources
Beta strandi1617 – 16248Combined sources
Turni1625 – 16273Combined sources
Beta strandi1628 – 16358Combined sources
Helixi1638 – 16403Combined sources
Beta strandi1642 – 16509Combined sources
Beta strandi1653 – 166412Combined sources

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2R15X-ray2.24A/B1459-1667[»]
2Y23X-ray2.50A1141-1447[»]
2Y25X-ray3.50A/B/C/D1357-1667[»]
3RBSX-ray1.85A1247-1447[»]
DisProtiDP00517.
ProteinModelPortaliP52179.
SMRiP52179. Positions 273-734, 751-834, 930-1024, 1039-1666.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP52179.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati182 – 18761
Repeati188 – 19362
Repeati194 – 19963
Repeati200 – 20564
Repeati206 – 21165
Repeati212 – 21766
Domaini277 – 36892Ig-like C2-type 1Add
BLAST
Domaini396 – 498103Ig-like C2-type 2Add
BLAST
Domaini512 – 60796Fibronectin type-III 1PROSITE-ProRule annotationAdd
BLAST
Domaini640 – 73495Fibronectin type-III 2PROSITE-ProRule annotationAdd
BLAST
Domaini741 – 83494Fibronectin type-III 3PROSITE-ProRule annotationAdd
BLAST
Domaini933 – 1034102Fibronectin type-III 4PROSITE-ProRule annotationAdd
BLAST
Domaini1041 – 1140100Fibronectin type-III 5PROSITE-ProRule annotationAdd
BLAST
Domaini1132 – 123099Ig-like C2-type 3Add
BLAST
Domaini1358 – 144487Ig-like C2-type 4Add
BLAST
Domaini1573 – 166290Ig-like C2-type 5Add
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni182 – 217366 X 6 AA tandem repeatsAdd
BLAST

Sequence similaritiesi

Contains 5 fibronectin type-III domains.PROSITE-ProRule annotation

Keywords - Domaini

Immunoglobulin domain, Repeat

Phylogenomic databases

eggNOGiNOG281933.
GeneTreeiENSGT00760000119038.
HOGENOMiHOG000293283.
HOVERGENiHBG004977.
InParanoidiP52179.
OMAiYIIESRY.
OrthoDBiEOG7MSMN2.
PhylomeDBiP52179.
TreeFamiTF331825.

Family and domain databases

Gene3Di2.60.40.10. 12 hits.
InterProiIPR003961. Fibronectin_type3.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013098. Ig_I-set.
IPR003599. Ig_sub.
IPR003598. Ig_sub2.
[Graphical view]
PfamiPF00041. fn3. 5 hits.
PF07679. I-set. 5 hits.
[Graphical view]
SMARTiSM00060. FN3. 5 hits.
SM00409. IG. 3 hits.
SM00408. IGc2. 1 hit.
[Graphical view]
SUPFAMiSSF49265. SSF49265. 3 hits.
PROSITEiPS50853. FN3. 5 hits.
PS50835. IG_LIKE. 4 hits.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: P52179-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MSLPFYQRCH QHYDLSYRNK DVRSTVSHYQ REKKRSAVYT QGSTAYSSRS
60 70 80 90 100
SAAHRRESEA FRRASASSSQ QQASQHALSS EVSRKAASAY DYGSSHGLTD
110 120 130 140 150
SSLLLDDYSS KLSPKPKRAK HSLLSGEEKE NLPSDYMVPI FSGRQKHVSG
160 170 180 190 200
ITDTEEERIK EAAAYIAQRN LLASEEGITT SKQSTASKQT TASKQSTASK
210 220 230 240 250
QSTASKQSTA SRQSTASRQS VVSKQATSAL QQEETSEKKS RKVVIREKAE
260 270 280 290 300
RLSLRKTLEE TETYHAKLNE DHLLHAPEFI IKPRSHTVWE KENVKLHCSI
310 320 330 340 350
AGWPEPRVTW YKNQVPINVH ANPGKYIIES RYGMHTLEIN GCDFEDTAQY
360 370 380 390 400
RASAMNVKGE LSAYASVVVK RYKGEFDETR FHAGASTMPL SFGVTPYGYA
410 420 430 440 450
SRFEIHFDDK FDVSFGREGE TMSLGCRVVI TPEIKHFQPE IQWYRNGVPL
460 470 480 490 500
SPSKWVQTLW SGERATLTFS HLNKEDEGLY TIRVRMGEYY EQYSAYVFVR
510 520 530 540 550
DADAEIEGAP AAPLDVKCLE ANKDYIIISW KQPAVDGGSP ILGYFIDKCE
560 570 580 590 600
VGTDSWSQCN DTPVKFARFP VTGLIEGRSY IFRVRAVNKM GIGFPSRVSE
610 620 630 640 650
PVAALDPAEK ARLKSRPSAP WTGQIIVTEE EPSEGIVPGP PTDLSVTEAT
660 670 680 690 700
RSYVVLSWKP PGQRGHEGIM YFVEKCEAGT ENWQRVNTEL PVKSPRFALF
710 720 730 740 750
DLAEGKSYCF RVRCSNSAGV GEPSEATEVT VVGDKLDIPK APGKIIPSRN
760 770 780 790 800
TDTSVVVSWE ESKDAKELVG YYIEASVAGS GKWEPCNNNP VKGSRFTCHG
810 820 830 840 850
LVTGQSYIFR VRAVNAAGLS EYSQDSEAIE VKAAIGGGVS PDVCPALSDE
860 870 880 890 900
PGGLTASRGR VHEASPPTFQ KDALLGSKPN KPSLPSSSQN LGQTEVSKVS
910 920 930 940 950
ETVQEELTPP PQKAAPQGKS KSDPLKKKTD RAPPSPPCDI TCLESFRDSM
960 970 980 990 1000
VLGWKQPDKI GGAEITGYYV NYREVIDGVP GKWREANVKA VSEEAYKISN
1010 1020 1030 1040 1050
LKENMVYQFQ VAAMNMAGLG APSAVSECFK CEEWTIAVPG PPHSLKCSEV
1060 1070 1080 1090 1100
RKDSLVLQWK PPVHSGRTPV TGYFVDLKEA KAKEDQWRGL NEAAIKNVYL
1110 1120 1130 1140 1150
KVRGLKEGVS YVFRVRAINQ AGVGKPSDLA GPVVAETRPG TKEVVVNVDD
1160 1170 1180 1190 1200
DGVISLNFEC DKMTPKSEFS WSKDYVSTED SPRLEVESKG NKTKMTFKDL
1210 1220 1230 1240 1250
GMDDLGIYSC DVTDTDGIAS SYLIDEEELK RLLALSHEHK FPTVPVKSEL
1260 1270 1280 1290 1300
AVEILEKGQV RFWMQAEKLS GNAKVNYIFN EKEIFEGPKY KMHIDRNTGI
1310 1320 1330 1340 1350
IEMFMEKLQD EDEGTYTFQL QDGKATNHST VVLVGDVFKK LQKEAEFQRQ
1360 1370 1380 1390 1400
EWIRKQGPHF VEYLSWEVTG ECNVLLKCKV ANIKKETHIV WYKDEREISV
1410 1420 1430 1440 1450
DEKHDFKDGI CTLLITEFSK KDAGIYEVIL KDDRGKDKSR LKLVDEAFKE
1460 1470 1480 1490 1500
LMMEVCKKIA LSATDLKIQS TAEGIQLYSF VTYYVEDLKV NWSHNGSAIR
1510 1520 1530 1540 1550
YSDRVKTGVT GEQIWLQINE PTPNDKGKYV MELFDGKTGH QKTVDLSGQA
1560 1570 1580 1590 1600
YDEAYAEFQR LKQAAIAEKN RARVLGGLPD VVTIQEGKAL NLTCNVWGDP
1610 1620 1630 1640 1650
PPEVSWLKNE KALASDDHCN LKFEAGRTAY FTINGVSTAD SGKYGLVVKN
1660 1670 1680
KYGSETSDFT VSVFIPEEEA RMAALESLKG GKKAK
Length:1,685
Mass (Da):187,627
Last modified:November 4, 2008 - v2
Checksum:iF0DBB25EB6323DF8
GO
Isoform 2 (identifier: P52179-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     836-931: Missing.

Show »
Length:1,589
Mass (Da):177,700
Checksum:iAB161B6C31ED4FDC
GO

Sequence cautioni

The sequence CAA48833.1 differs from that shown. Reason: Erroneous initiation.

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti247 – 2471E → G in CAA48833. (PubMed:7505783)Curated
Sequence conflicti442 – 4421Q → R in CAA48833. (PubMed:7505783)Curated
Sequence conflicti599 – 5991S → F in AAI16184. (PubMed:15489334)Curated
Sequence conflicti601 – 6011P → A in CAA48833. (PubMed:7505783)Curated
Sequence conflicti615 – 6151S → G in AAI16184. (PubMed:15489334)Curated
Sequence conflicti616 – 62510RPSAPWTGQI → PLSTLDWTV in CAA48833. (PubMed:7505783)Curated
Sequence conflicti776 – 7761S → N in CAA48833. (PubMed:7505783)Curated
Sequence conflicti793 – 7942GS → TH in CAA48833. (PubMed:7505783)Curated
Sequence conflicti992 – 9921S → R in CAA48833. (PubMed:7505783)Curated
Sequence conflicti1001 – 10011L → S in BAC86128. (PubMed:14702039)Curated
Sequence conflicti1080 – 10801Missing in CAA48833. (PubMed:7505783)Curated
Sequence conflicti1141 – 11411T → R in CAA48833. (PubMed:7505783)Curated
Sequence conflicti1615 – 16162SD → QT in CAA48833. (PubMed:7505783)Curated
Sequence conflicti1617 – 16171D → G in BAC86128. (PubMed:14702039)Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti22 – 221V → L.
Corresponds to variant rs1791085 [ dbSNP | Ensembl ].
VAR_047221
Natural varianti181 – 1811S → P.3 Publications
Corresponds to variant rs1962519 [ dbSNP | Ensembl ].
VAR_047222
Natural varianti215 – 2151T → M.
Corresponds to variant rs2230165 [ dbSNP | Ensembl ].
VAR_047223
Natural varianti341 – 3411G → A.4 Publications
Corresponds to variant rs8099021 [ dbSNP | Ensembl ].
VAR_047224
Natural varianti600 – 6001E → V.
Corresponds to variant rs9807556 [ dbSNP | Ensembl ].
VAR_047225
Natural varianti960 – 9601I → T.3 Publications
Corresponds to variant rs1071600 [ dbSNP | Ensembl ].
VAR_047226
Natural varianti1408 – 14081D → N.
Corresponds to variant rs3765623 [ dbSNP | Ensembl ].
VAR_047227
Natural varianti1453 – 14531M → T.
Corresponds to variant rs16944397 [ dbSNP | Ensembl ].
VAR_047228

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei836 – 93196Missing in isoform 2. 2 PublicationsVSP_035663Add
BLAST

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ621424 mRNA. Translation: CAF18565.1.
AK125322 mRNA. Translation: BAC86128.1.
AP005329 Genomic DNA. No translation available.
AP005431 Genomic DNA. No translation available.
BC116183 mRNA. Translation: AAI16184.1.
X69090 mRNA. Translation: CAA48833.1. Different initiation.
CCDSiCCDS45823.1. [P52179-2]
CCDS45824.1. [P52179-1]
PIRiS42167.
RefSeqiNP_003794.3. NM_003803.3. [P52179-1]
NP_062830.1. NM_019856.1. [P52179-2]
UniGeneiHs.464469.

Genome annotation databases

EnsembliENST00000261606; ENSP00000261606; ENSG00000101605. [P52179-2]
ENST00000356443; ENSP00000348821; ENSG00000101605. [P52179-1]
GeneIDi8736.
KEGGihsa:8736.
UCSCiuc002klp.3. human. [P52179-1]
uc002klq.3. human. [P52179-2]

Polymorphism databases

DMDMi212276443.

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ621424 mRNA. Translation: CAF18565.1 .
AK125322 mRNA. Translation: BAC86128.1 .
AP005329 Genomic DNA. No translation available.
AP005431 Genomic DNA. No translation available.
BC116183 mRNA. Translation: AAI16184.1 .
X69090 mRNA. Translation: CAA48833.1 . Different initiation.
CCDSi CCDS45823.1. [P52179-2 ]
CCDS45824.1. [P52179-1 ]
PIRi S42167.
RefSeqi NP_003794.3. NM_003803.3. [P52179-1 ]
NP_062830.1. NM_019856.1. [P52179-2 ]
UniGenei Hs.464469.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
2R15 X-ray 2.24 A/B 1459-1667 [» ]
2Y23 X-ray 2.50 A 1141-1447 [» ]
2Y25 X-ray 3.50 A/B/C/D 1357-1667 [» ]
3RBS X-ray 1.85 A 1247-1447 [» ]
DisProti DP00517.
ProteinModelPortali P52179.
SMRi P52179. Positions 273-734, 751-834, 930-1024, 1039-1666.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

DIPi DIP-59649N.
IntActi P52179. 6 interactions.
STRINGi 9606.ENSP00000348821.

PTM databases

PhosphoSitei P52179.

Polymorphism databases

DMDMi 212276443.

Proteomic databases

MaxQBi P52179.
PaxDbi P52179.
PRIDEi P52179.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000261606 ; ENSP00000261606 ; ENSG00000101605 . [P52179-2 ]
ENST00000356443 ; ENSP00000348821 ; ENSG00000101605 . [P52179-1 ]
GeneIDi 8736.
KEGGi hsa:8736.
UCSCi uc002klp.3. human. [P52179-1 ]
uc002klq.3. human. [P52179-2 ]

Organism-specific databases

CTDi 8736.
GeneCardsi GC18M003056.
H-InvDB HIX0017329.
HGNCi HGNC:7613. MYOM1.
HPAi HPA014305.
MIMi 603508. gene.
neXtProti NX_P52179.
PharmGKBi PA31418.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG281933.
GeneTreei ENSGT00760000119038.
HOGENOMi HOG000293283.
HOVERGENi HBG004977.
InParanoidi P52179.
OMAi YIIESRY.
OrthoDBi EOG7MSMN2.
PhylomeDBi P52179.
TreeFami TF331825.

Miscellaneous databases

EvolutionaryTracei P52179.
GeneWikii MYOM1.
GenomeRNAii 8736.
NextBioi 32769.
PROi P52179.
SOURCEi Search...

Gene expression databases

Bgeei P52179.
CleanExi HS_MYOM1.
ExpressionAtlasi P52179. baseline and differential.
Genevestigatori P52179.

Family and domain databases

Gene3Di 2.60.40.10. 12 hits.
InterProi IPR003961. Fibronectin_type3.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013098. Ig_I-set.
IPR003599. Ig_sub.
IPR003598. Ig_sub2.
[Graphical view ]
Pfami PF00041. fn3. 5 hits.
PF07679. I-set. 5 hits.
[Graphical view ]
SMARTi SM00060. FN3. 5 hits.
SM00409. IG. 3 hits.
SM00408. IGc2. 1 hit.
[Graphical view ]
SUPFAMi SSF49265. SSF49265. 3 hits.
PROSITEi PS50853. FN3. 5 hits.
PS50835. IG_LIKE. 4 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "SUMO modification of the M-band protein myomesin."
    Hayess K., Matschke K., Fuerst D.O.
    Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), VARIANTS ALA-341 AND THR-960.
    Tissue: Skeletal muscle.
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANTS PRO-181; ALA-341 AND THR-960.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2), VARIANTS PRO-181 AND ALA-341.
  5. "The globular head domain of titin extends into the center of the sarcomeric M band. cDNA cloning, epitope mapping and immunoelectron microscopy of two titin-associated proteins."
    Vinkemeier U., Obermann W., Weber K., Fuerst D.O.
    J. Cell Sci. 106:319-330(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 99-1685 (ISOFORM 2), VARIANTS PRO-181; ALA-341 AND THR-960.
    Tissue: Skeletal muscle.
  6. "Characterization of MR-1, a novel myofibrillogenesis regulator in human muscle."
    Li T.-B., Liu X.-H., Feng S., Hu Y., Yang W.-X., Han Y., Wang Y.-G., Gong L.-M.
    Acta Biochim. Biophys. Sin. 36:412-418(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH PNKD.

Entry informationi

Entry nameiMYOM1_HUMAN
AccessioniPrimary (citable) accession number: P52179
Secondary accession number(s): Q14BD6, Q6H969, Q6ZUU0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: November 4, 2008
Last modified: October 29, 2014
This is version 124 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome 18
    Human chromosome 18: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  6. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3