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Protein

Putative arsenical pump membrane protein

Gene

yfjV

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein uncertaini

Functioni

Involved in arsenical resistance. Thought to form the channel of an arsenite pump (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processArsenical resistance

Enzyme and pathway databases

BioCyciEcoCyc:G7375-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative arsenical pump membrane protein
Gene namesi
Name:yfjV
Synonyms:ypjM
Ordered Locus Names:b2641
ORF Names:b2639, b2640
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13208. yfjV.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei22 – 42HelicalSequence analysisAdd BLAST21
Transmembranei45 – 65HelicalSequence analysisAdd BLAST21
Transmembranei87 – 107HelicalSequence analysisAdd BLAST21
Transmembranei137 – 157HelicalSequence analysisAdd BLAST21
Transmembranei183 – 203HelicalSequence analysisAdd BLAST21
Transmembranei225 – 245HelicalSequence analysisAdd BLAST21
Transmembranei246 – 266HelicalSequence analysisAdd BLAST21
Transmembranei280 – 300HelicalSequence analysisAdd BLAST21
Transmembranei316 – 336HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_0000201481‹1 – 338Putative arsenical pump membrane proteinAdd BLAST›338

Interactioni

Protein-protein interaction databases

DIPiDIP-12087N.
IntActiP52137. 1 interactor.

Structurei

3D structure databases

ProteinModelPortaliP52137.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ArsB family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG1055. LUCA.
HOGENOMiHOG000005271.
InParanoidiP52137.
PhylomeDBiP52137.

Family and domain databases

CDDicd01118. ArsB_permease. 1 hit.
InterProiView protein in InterPro
IPR000802. Arsenical_pump_ArsB.
PfamiView protein in Pfam
PF02040. ArsB. 1 hit.
PRINTSiPR00758. ARSENICPUMP.
TIGRFAMsiTIGR00935. 2a45. 1 hit.

Sequencei

Sequence statusi: Fragment.

P52137-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
RALFTWKVLL GAAVDALFAN DGAALILTPI VIAMLIALGF SQGTTLAFVM
60 70 80 90 100
AAGFIADTAS LPLIVSNLVN IVSADFFGLS FAQYASVMIS VDAAAIAATL
110 120 130 140 150
IMLYLFFRRV IPATYXVSLL KTPASAIKDL ATFRAGWIVL LLLLVGFFFL
160 170 180 190 200
EPQGILVSAI AAAGAAVLFV VAKRGHSINT GKVLRGAPWQ IVIFSLGMYI
210 220 230 240 250
VVYGLRNAGF TEYLSGVLNL LADKGLWAAT FGTGFLTAFL SSVMNNMPTV
260 270 280 290 300
LIGALSIDGS TATGVVKEAM IYANVIGCDL GPKITPIGSL ATLLWLHVLA
310 320 330
QKNMTITWGY YFRTGIVMTV PVLFVTLAAL AWRLSVTL
Length:338
Mass (Da):35,811
Last modified:October 1, 1996 - v1
Checksum:iC0B2DF18AED8352A
GO

Sequence cautioni

The sequence AAA79807 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei11

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U36840 Genomic DNA. Translation: AAA79807.1. Different initiation.
U36840 Genomic DNA. Translation: AAA79808.1. Different termination.
U36840 Genomic DNA. Translation: AAA79809.1. Frameshift.
U00096 Genomic DNA. No translation available.
PIRiT08650.
T08651.
T08652.

Similar proteinsi

Entry informationi

Entry nameiYFJV_ECOLI
AccessioniPrimary (citable) accession number: P52137
Secondary accession number(s): P76607, P76608, P76609
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: August 30, 2017
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Caution

This is a truncated ORF. Compared to E.coli W3110, the strain MG1655 has an apparent deletion of about 6 kb which seems to truncate this putative ArsB homolog.Curated
Could be the product of a pseudogene.Curated

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families