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Protein

Putative arsenical pump membrane protein

Gene

yfjV

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein uncertaini

Functioni

Involved in arsenical resistance. Thought to form the channel of an arsenite pump (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Arsenical resistance

Enzyme and pathway databases

BioCyciEcoCyc:G7375-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative arsenical pump membrane protein
Gene namesi
Name:yfjV
Synonyms:ypjM
Ordered Locus Names:b2641
ORF Names:b2639, b2640
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13208. yfjV.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei22 – 4221HelicalSequence analysisAdd
BLAST
Transmembranei45 – 6521HelicalSequence analysisAdd
BLAST
Transmembranei87 – 10721HelicalSequence analysisAdd
BLAST
Transmembranei137 – 15721HelicalSequence analysisAdd
BLAST
Transmembranei183 – 20321HelicalSequence analysisAdd
BLAST
Transmembranei225 – 24521HelicalSequence analysisAdd
BLAST
Transmembranei246 – 26621HelicalSequence analysisAdd
BLAST
Transmembranei280 – 30021HelicalSequence analysisAdd
BLAST
Transmembranei316 – 33621HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini‹1 – 338›338Putative arsenical pump membrane proteinPRO_0000201481Add
BLAST

Interactioni

Protein-protein interaction databases

DIPiDIP-12087N.
IntActiP52137. 1 interaction.
STRINGi316407.85675502.

Structurei

3D structure databases

ProteinModelPortaliP52137.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ArsB family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG1055. LUCA.
HOGENOMiHOG000005271.
InParanoidiP52137.
PhylomeDBiP52137.

Family and domain databases

InterProiIPR000802. Arsenical_pump_ArsB.
[Graphical view]
PfamiPF02040. ArsB. 1 hit.
[Graphical view]
PRINTSiPR00758. ARSENICPUMP.
TIGRFAMsiTIGR00935. 2a45. 1 hit.

Sequencei

Sequence statusi: Fragment.

P52137-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
RALFTWKVLL GAAVDALFAN DGAALILTPI VIAMLIALGF SQGTTLAFVM
60 70 80 90 100
AAGFIADTAS LPLIVSNLVN IVSADFFGLS FAQYASVMIS VDAAAIAATL
110 120 130 140 150
IMLYLFFRRV IPATYXVSLL KTPASAIKDL ATFRAGWIVL LLLLVGFFFL
160 170 180 190 200
EPQGILVSAI AAAGAAVLFV VAKRGHSINT GKVLRGAPWQ IVIFSLGMYI
210 220 230 240 250
VVYGLRNAGF TEYLSGVLNL LADKGLWAAT FGTGFLTAFL SSVMNNMPTV
260 270 280 290 300
LIGALSIDGS TATGVVKEAM IYANVIGCDL GPKITPIGSL ATLLWLHVLA
310 320 330
QKNMTITWGY YFRTGIVMTV PVLFVTLAAL AWRLSVTL
Length:338
Mass (Da):35,811
Last modified:October 1, 1996 - v1
Checksum:iC0B2DF18AED8352A
GO

Sequence cautioni

The sequence AAA79807.1 differs from that shown. Reason: Erroneous initiation. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U36840 Genomic DNA. Translation: AAA79807.1. Different initiation.
U36840 Genomic DNA. Translation: AAA79808.1. Different termination.
U36840 Genomic DNA. Translation: AAA79809.1. Frameshift.
U00096 Genomic DNA. No translation available.
PIRiT08650.
T08651.
T08652.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U36840 Genomic DNA. Translation: AAA79807.1. Different initiation.
U36840 Genomic DNA. Translation: AAA79808.1. Different termination.
U36840 Genomic DNA. Translation: AAA79809.1. Frameshift.
U00096 Genomic DNA. No translation available.
PIRiT08650.
T08651.
T08652.

3D structure databases

ProteinModelPortaliP52137.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-12087N.
IntActiP52137. 1 interaction.
STRINGi316407.85675502.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

EchoBASEiEB3000.
EcoGeneiEG13208. yfjV.

Phylogenomic databases

eggNOGiCOG1055. LUCA.
HOGENOMiHOG000005271.
InParanoidiP52137.
PhylomeDBiP52137.

Enzyme and pathway databases

BioCyciEcoCyc:G7375-MONOMER.

Family and domain databases

InterProiIPR000802. Arsenical_pump_ArsB.
[Graphical view]
PfamiPF02040. ArsB. 1 hit.
[Graphical view]
PRINTSiPR00758. ARSENICPUMP.
TIGRFAMsiTIGR00935. 2a45. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.

Entry informationi

Entry nameiYFJV_ECOLI
AccessioniPrimary (citable) accession number: P52137
Secondary accession number(s): P76607, P76608, P76609
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: February 17, 2016
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Caution

This is a truncated ORF. Compared to E.coli W3110, the strain MG1655 has an apparent deletion of about 6 kb which seems to truncate this putative ArsB homolog.Curated
Could be the product of a pseudogene.Curated

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.